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Names | |
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IUPAC name
methyl 3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
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Other names
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Identifiers | |
3D model (
JSmol)
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ChEMBL | |
ChemSpider | |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C10H17NO3 | |
Molar mass | 199.250 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Methylecgonine, also known as ecgonine methyl ester is a prominent tropane alkaloid found in coca leaves. [1] It is metabolite of cocaine, [2] and may be used as a precursor for it. It also occurs as minor alkaloid in roots of many Datura species such as Datura stramonium [3] and Datura innoxia. [4]
It is the last step before cocaine is biosynthesized in coca plants with the help of BAHD acyltransferase. [5]
Animals study suggest that it has beneficial effect on cognition and protects against cocaine lethality. [6] [7] It showed inhibition of sodium channels only at very high dosages. [8]
![]() | |
Names | |
---|---|
IUPAC name
methyl 3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
| |
Other names
| |
Identifiers | |
3D model (
JSmol)
|
|
ChEMBL | |
ChemSpider | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C10H17NO3 | |
Molar mass | 199.250 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Methylecgonine, also known as ecgonine methyl ester is a prominent tropane alkaloid found in coca leaves. [1] It is metabolite of cocaine, [2] and may be used as a precursor for it. It also occurs as minor alkaloid in roots of many Datura species such as Datura stramonium [3] and Datura innoxia. [4]
It is the last step before cocaine is biosynthesized in coca plants with the help of BAHD acyltransferase. [5]
Animals study suggest that it has beneficial effect on cognition and protects against cocaine lethality. [6] [7] It showed inhibition of sodium channels only at very high dosages. [8]