Testosterone , the base androgen of most androgen esters.
This is a list of
androgen esters , including
esters (as well as
ethers ) of
natural
androgens like
testosterone and
dihydrotestosterone (DHT) and
synthetic
anabolic–androgenic steroids (AAS) like
nandrolone (19-nortestosterone).
Esters of natural AAS
Testosterone esters
Marketed
Many esters of testosterone have been marketed, including the following major esters:
[1]
[2]
Testosterone caproate (component of
Omnadren and
Triormon Depositum )
Testosterone cypionate (Depo-Testosterone, numerous others)
Testosterone decanoate (component of
Sustanon 250 )
Testosterone enanthate (Delatestryl, numerous others) (component of
Testoviron Depot )
Testosterone isobutyrate (Agovirin-Depot, Perandren M, Testocryst, Virex-Cryst; component of
Femandren M/Folivirin )
Testosterone isocaproate (component of
Omnadren ,
Sustanon 100 , and
Sustanon 250 )
Testosterone phenylpropionate (component of
Omnadren ,
Sustanon 100 , and
Sustanon 250 )
Testosterone propionate (Testoviron, numerous others) (component of
Omnadren ,
Sustanon 100 ,
Sustanon 250 , and
Testoviron Depot )
Testosterone undecanoate (Aveed, Andriol, Nebido, Jatenzo, numerous others)
And the following less commonly used esters:
[1]
[2]
Testosterone acetate (Aceto-Sterandryl, Aceto-Testoviron, Amolisin, Androtest A, Deposteron, Farmatest, Perandrone A)
Testosterone cyclohexylpropionate (Andromar, Femolone, Telipex Retard; component of
Trioestrine Retard )
Testosterone enantate benzilic acid hydrazone (component of
Climacteron )
Testosterone furoate (Furotest)
Testosterone hexahydrobenzoate (Sterandryl Retard; component of
Trinestril AP )
Testosterone hexahydrobenzylcarbonate (Lontanyl)
Testosterone hexyloxyphenylpropionate (Andradurin)
Testosterone ketolaurate (Androdurin; component of
Testosid-Depot and
Klimanosid R-Depot )
Testosterone nicotinate (Bolfortan, Linobol)
Testosterone phenylacetate (Perandren, Androject)
Testosterone phosphate (Telipex Aquosum)
Testosterone undecylenate (component of
Durasteron and
Triolandren )
Testosterone valerate (component of
Deposterona and
Triolandren )
[3]
Never marketed
The following major testosterone ester has not been marketed:
[1]
[2]
Testosterone buciclate (20 Aet-1, CDB-1781) – a very long-acting testosterone ester that was under development but ultimately did not reach the market
[4]
[5]
And the following less commonly known testosterone esters have also not been marketed:
[1]
[2]
Dihydrotestosterone esters
Marketed
Several esters of
dihydrotestosterone (DHT;
androstanolone, stanolone ) have also been marketed, including the following:
[8]
[9]
Never marketed
The following esters of DHT have not been marketed:
[8]
[9]
Testifenon (chlorphenacyl DHT ester) is a
nitrogen mustard
ester of DHT that was developed as a
cytostatic antineoplastic agent but was never marketed.
[10]
Esters of other natural AAS
Marketed
The following esters of other natural AAS have been marketed:
Never marketed
And the following have not been marketed:
Sturamustine is a
nitrosourea
ester of
dehydroepiandrosterone (DHEA) that was developed as a
cytostatic antineoplastic agent but was never marketed.
[12]
[13]
Ethers of natural AAS
Marketed
Although not esters, the following ethers of natural AAS have been marketed as well:
Never marketed
And the following have not been marketed:
Esters of synthetic AAS
Methandriol esters
Marketed
Never marketed
Nandrolone esters
Marketed
Many esters of the synthetic AAS
nandrolone (19-nortestosterone) have been marketed, including the following major esters:
[14]
[15]
[16]
And the following less commonly used esters:
[14]
[15]
[16]
Nandrolone caproate (Anabolin Depot)
Nandrolone cyclohexanecarboxylate (Nor-Durandron, Norlongandron)
Nandrolone cyclohexylpropionate (Andol, Fherbolico, Megabolin, Megabolin Retar, Pluropon, Proteron-Depot, Sanabolicum)
Nandrolone cypionate (Anabo, Depo-Nortestonate, Dynabol, Nortestrionate, Pluropon, Sterocrinolo)
Nandrolone furylpropionate (Demelon)
Nandrolone hexyloxyphenylpropionate (Anador, Anadur, Anadurine)
Nandrolone hydrogen succinate (Anabolico, Menidrabol)
Nandrolone laurate (Clinibolin, Fortadex, Laurabolin)
Nandrolone propionate (Anabolicus, Nor-Anabol, Nortesto, Norbyol 19, Pondus, Testobolin)
Nandrolone sulfate (Keratyl, Nandrol, Nandain, Colirio Ocul Nandrol)
Nandrolone undecanoate (Dynabolin, Dynabolon, Psychobolan)
Never marketed
The following nandrolone esters exist but were never marketed:
LS-1727 is a
nitroso
carbamate
ester of nandrolone that was developed as a
cytostatic antineoplastic agent but was never marketed.
[19]
Trenbolone esters
Marketed
A few esters of the synthetic AAS
trenbolone have been marketed, including the following esters:
Never marketed
The following trenbolone esters exist but were never marketed:
Esters of other synthetic AAS
Marketed
Many esters of other synthetic AAS have been marketed as well, including the following:
Bolandiol dipropionate (Anabiol, Storinal)
Bolazine capronate (bolazine caproate) (Roxilon Inject)
Boldenone acetate (Equilon 100)
Boldenone cypionate (Equilon 100)
Boldenone propionate (Equilon 100)
Boldenone undecylenate (boldenone undecenoate) (Boldane, Equilon 100, Equipoise, Parenabol, Vebonol, others)
Clostebol acetate (Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit)
Clostebol caproate (Macrobin-Depot)
Clostebol propionate (Yonchlon)
Drostanolone propionate (Masteron, Drolban, Masteril, Mastisol, Metormon, Permastril)
Metenolone acetate (Primobolan, Primobolan S, Primonabol, Nibal)
Metenolone enantate (Primobolan Depot)
Norclostebol acetate (Anabol 4-19)
Oxabolone cipionate (Steranabol Depo, Steranabol Ritardo)
Propetandrol (norethandrolone 3β-propionate) (Solevar)
Stenbolone acetate (Stenobolone, Anatrofin)
Never marketed
Whereas the following have not been marketed:
Ethers of synthetic AAS
Marketed
Although not esters, the following ethers of synthetic AAS have been marketed as well:
Never marketed
And the following have not been marketed:
See also
References
^
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b
c
d
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ISBN
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^
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b
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f
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The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . Springer. pp. 642–.
ISBN
978-1-4757-2085-3 .
^ William Llewellyn (2011).
Anabolics . Molecular Nutrition Llc. pp. 437–.
ISBN
978-0-9828280-1-4 .
^ E. Nieschlag; H. M. Behre (1 April 2004).
Testosterone: Action, Deficiency, Substitution . Cambridge University Press. pp. 692–.
ISBN
978-1-139-45221-2 .
^ Shalender Bhasin (13 February 1996).
Pharmacology, Biology, and Clinical Applications of Androgens: Current Status and Future Prospects . John Wiley & Sons. pp. 471–.
ISBN
978-0-471-13320-9 .
^
"R&D Research" . www.evestra.com . Archived from
the original on 2017-09-29.
^ Ahmed G, Elger W, Meece F, Nair HB, Schneider B, Wyrwa R, Nickisch K (October 2017). "A prodrug design for improved oral absorption and reduced hepatic interaction". Bioorg. Med. Chem . 25 (20): 5569–5575.
doi :
10.1016/j.bmc.2017.08.027 .
PMID
28886996 .
^
a
b J. Elks (14 November 2014).
The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . Springer. pp. 640–.
ISBN
978-1-4757-2085-3 .
^
a
b I.K. Morton; Judith M. Hall (6 December 2012).
Concise Dictionary of Pharmacological Agents: Properties and Synonyms . Springer Science & Business Media. pp. 261–.
ISBN
978-94-011-4439-1 .
^ Lagova ND, Sof'ina ZP, Shkodinskaia EN, Kurdiumova KN, Valueva IM (1988). "[The antineoplastic activity of testiphenon]". Vopr Onkol (in Russian). 34 (11): 1363–8.
PMID
3201773 .
^ George W.A Milne (8 May 2018).
Drugs: Synonyms and Properties: Synonyms and Properties . Taylor & Francis. pp. 67–.
ISBN
978-1-351-78989-9 .
^ J. Elks (14 November 2014).
The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . Springer. p. 1122.
ISBN
978-1-4757-2085-3 .
^ Chavis C, de Gourcy C, Borgna JL, Imbach JL (1982). "New steroidal nitrosoureas". Steroids . 39 (2): 129–47.
doi :
10.1016/0039-128x(82)90081-2 .
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^
a
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The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies . Springer. pp. 660–.
ISBN
978-1-4757-2085-3 .
^
a
b
Index Nominum 2000: International Drug Directory . Taylor & Francis. January 2000. pp. 716–717.
ISBN
978-3-88763-075-1 .
^
a
b I.K. Morton; Judith M. Hall (6 December 2012).
Concise Dictionary of Pharmacological Agents: Properties and Synonyms . Springer Science & Business Media.
ISBN
978-94-011-4439-1 .
^ Lerner, Leonard J.; Holthaus, Fred J.; Thompson, Charles R. (1959). "A myotrophic agent and gonadotrophin inhibitor, 19-nortestosterone-17-benzoate". Endocrinology . 64 (6): 1010–1016.
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^ Boschann, H. -W. (1955). "Cytologische Untersuchungen über die Wirkung von Androgenen am atrophischen Vaginalepithel in Abhängigkeit von Dosierung und Applikationsart". Archiv für Gynäkologie . 187 (1): 39–64.
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^ Hartley-Asp B, Wilkinson R, Venitt S, Harrap KR (1981). "Studies on the mechanism of action of LS 1727, a nitrosocarbamate of 19-nortestosterone". Acta Pharmacol Toxicol (Copenh) . 48 (2): 129–38.
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PMID
6167141 .
Androgens (incl.
AAS Tooltip anabolic–androgenic steroid )
Antiandrogens
AR Tooltip Androgen receptor
antagonists
Steroidogenesis inhibitors
Antigonadotropins
D2 receptor
antagonists (
prolactin releasers ) (e.g.,
domperidone ,
metoclopramide ,
risperidone ,
haloperidol ,
chlorpromazine ,
sulpiride )
Estrogens (e.g.,
bifluranol ,
diethylstilbestrol ,
estradiol ,
estradiol esters ,
ethinylestradiol ,
ethinylestradiol sulfonate ,
paroxypropione )
GnRH agonists (e.g.,
leuprorelin )
GnRH antagonists (e.g.,
cetrorelix )
Progestogens (incl.,
chlormadinone acetate ,
cyproterone acetate ,
hydroxyprogesterone caproate ,
gestonorone caproate ,
medroxyprogesterone acetate ,
megestrol acetate )
Others
AR Tooltip Androgen receptor
Agonists
SARMs Tooltip Selective androgen receptor modulator Antagonists
GPRC6A