Look up mainframe in Wiktionary, the free dictionary.

A mainframe computer is a type of large data processing system.

Mainframe may also refer to:

• Mainframe Studios, a Canadian computer animation company founded as Mainframe Entertainment

• Mainframe (comics), several Marvel Comics characters
• Mainframe (G.I. Joe), a character in the G.I. Joe universe
• Mainframe, a character from the game Gunman Chronicles
• Mainframe, the city in the animated series ReBoot
• Tina "Mainframe" Cassidy, a character from the animated TV series COPS
• Mainframe, a character in Gene Wolfe's series of novels The Book of the Long Sun

This disambiguation page lists articles associated with the title Mainframe.
If an internal link led you here, you may wish to change the link to point directly to the intended article.