From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
MORC family CW-type zinc finger protein 3 is a
protein that in humans is encoded by the MORC3
gene.
[5]
[6]
This gene encodes a protein that localizes to the
nuclear matrix. The protein also has
RNA binding activity, and has a predicted
coiled-coil domain.
[6]
See also
References
Further reading
- Nagase T, Seki N, Tanaka A, et al. (1996).
"Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (4): 167–74, 199–210.
doi:
10.1093/dnares/2.4.167.
PMID
8590280.
- Bonaldo MF, Lennon G, Soares MB (1997).
"Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806.
doi:
10.1101/gr.6.9.791.
PMID
8889548.
- Hattori M, Fujiyama A, Taylor TD, et al. (2000).
"The DNA sequence of human chromosome 21". Nature. 405 (6784): 311–9.
Bibcode:
2000Natur.405..311H.
doi:
10.1038/35012518.
PMID
10830953.
- Kimura Y, Sakai F, Nakano O, et al. (2002).
"The newly identified human nuclear protein NXP-2 possesses three distinct domains, the nuclear matrix-binding, RNA-binding, and coiled-coil domains". J. Biol. Chem. 277 (23): 20611–7.
doi:
10.1074/jbc.M201440200.
PMID
11927593.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903.
Bibcode:
2002PNAS...9916899M.
doi:
10.1073/pnas.242603899.
PMC
139241.
PMID
12477932.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5.
doi:
10.1038/ng1285.
PMID
14702039.
- Rosendorff A, Sakakibara S, Lu S, et al. (2006).
"NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5308–13.
Bibcode:
2006PNAS..103.5308R.
doi:
10.1073/pnas.0601066103.
PMC
1459351.
PMID
16567619.
- Takahashi K, Yoshida N, Murakami N, et al. (2007).
"Dynamic regulation of p53 subnuclear localization and senescence by MORC3". Mol. Biol. Cell. 18 (5): 1701–9.
doi:
10.1091/mbc.E06-08-0747.
PMC
1855011.
PMID
17332504.