Makorin ring finger protein 3 is a
protein that in humans is encoded by the MKRN3
gene.[5]
Function
The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to
Prader–Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene.[citation needed]
Lee HS, Jin HS, Shim YS, Jeong HR, Kwon E, Choi V, Kim MC, Chung IS, Jeong SY, Hwang JS (2016). "Low Frequency of MKRN3 Mutations in Central Precocious Puberty Among Korean Girls". Horm. Metab. Res. 48 (2): 118–22.
doi:
10.1055/s-0035-1548938.
PMID25938887.
Makorin ring finger protein 3 is a
protein that in humans is encoded by the MKRN3
gene.[5]
Function
The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to
Prader–Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene.[citation needed]
Lee HS, Jin HS, Shim YS, Jeong HR, Kwon E, Choi V, Kim MC, Chung IS, Jeong SY, Hwang JS (2016). "Low Frequency of MKRN3 Mutations in Central Precocious Puberty Among Korean Girls". Horm. Metab. Res. 48 (2): 118–22.
doi:
10.1055/s-0035-1548938.
PMID25938887.