Lyons House may refer to:

in Australia

• Lyons House, a heritage listed house at 733 Port Hacking Rd, Dolans Bay, New South Wales.

in Ireland

• Lyons House, County Kildare, Ireland

in the United States (by state)

• Horace G. Lyons House, Berryton, Kansas, listed on the NRHP in Kansas
• Lyons House (Abbeville, Louisiana), listed on the NRHP in Louisiana
• Lyons House (Vinton, Louisiana), listed on the NRHP in Louisiana
• Benson H. Lyons House, Leesville, Louisiana, listed on the NRHP in Louisiana
• Joseph D. Lyons House, Sunderland, Maryland, listed on the NRHP in Maryland
• Byers-Lyons House, Pittsburgh, Pennsylvania, listed on the NRHP in Pennsylvania
• Frederick and Sallie Lyons House, Pleasanton, Texas, listed on the NRHP in Texas
• Oscar F. Lyons House, Peoa, Utah, listed on the NRHP in Utah

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