Combination of | |
---|---|
Lamivudine | nucleoside reverse transcriptase inhibitor |
Nevirapine | non-nucleoside reverse transcriptase inhibitor |
Zidovudine | nucleoside reverse transcriptase inhibitor |
Clinical data | |
Trade names | Duovir-N, Zidovex-LN, others [1] |
ATC code | |
Identifiers | |
CAS Number | |
ChemSpider |
|
Lamivudine/nevirapine/zidovudine (3TC/NVP/AZT) is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS. [2] It contains lamivudine, nevirapine, and zidovudine. [2] It is either used by itself or along with other antiretrovirals. [2] It is a recommended treatment in those who are pregnant. [2] It is taken by mouth twice a day. [2]
The medication is generally well tolerated. [1] Side effects are those of the underlying medications. [2] This includes rash, pancreatitis, low white blood cell levels, and muscle pain. [1] Use is not recommended in those with significant liver problems. [1] Use in pregnancy and breastfeeding appear to be safe. [1] The combination tablet is typically not appropriate for children. [2]
It is on the World Health Organization's List of Essential Medicines. [3] The combination is not commercially available in the United States as of 2018. [4]
Combination of | |
---|---|
Lamivudine | nucleoside reverse transcriptase inhibitor |
Nevirapine | non-nucleoside reverse transcriptase inhibitor |
Zidovudine | nucleoside reverse transcriptase inhibitor |
Clinical data | |
Trade names | Duovir-N, Zidovex-LN, others [1] |
ATC code | |
Identifiers | |
CAS Number | |
ChemSpider |
|
Lamivudine/nevirapine/zidovudine (3TC/NVP/AZT) is a fixed-dose combination antiretroviral medication used to treat HIV/AIDS. [2] It contains lamivudine, nevirapine, and zidovudine. [2] It is either used by itself or along with other antiretrovirals. [2] It is a recommended treatment in those who are pregnant. [2] It is taken by mouth twice a day. [2]
The medication is generally well tolerated. [1] Side effects are those of the underlying medications. [2] This includes rash, pancreatitis, low white blood cell levels, and muscle pain. [1] Use is not recommended in those with significant liver problems. [1] Use in pregnancy and breastfeeding appear to be safe. [1] The combination tablet is typically not appropriate for children. [2]
It is on the World Health Organization's List of Essential Medicines. [3] The combination is not commercially available in the United States as of 2018. [4]