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Names | |
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Other names
4-Hydroxy-3,3-dimethyl-2-oxobutanoic acid; 2-Dehydropantoic acid
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Identifiers | |
3D model (
JSmol)
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2242422 | |
ChEBI | |
ChemSpider | |
DrugBank | |
KEGG | |
PubChem
CID
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CompTox Dashboard (
EPA)
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Properties | |
C6H10O4 | |
Molar mass | 146.142 g·mol−1 |
Appearance | colorless or white |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Ketopantoic acid is the organic compound with the formula HOCH2(CH3)2CC(O)CO2H. At physiological conditions, ketopantoic acid exists as its conjugate base, ketopantoate (HOCH2(CH3)2CC(O)CO2−).
Its biosynthesis proceeds from ketoisovalerate by hydroxymethylation:
This conversion is catalyzed by ketopantoate hydroxymethyltransferase, which gives ketopantoate.
Ketopantoate is substrate for 2-dehydropantoate 2-reductase, [1] which produces pantoate, a precursor to pantothenic acid, a common prosthetic group. [2]
![]() | |
Names | |
---|---|
Other names
4-Hydroxy-3,3-dimethyl-2-oxobutanoic acid; 2-Dehydropantoic acid
| |
Identifiers | |
3D model (
JSmol)
|
|
2242422 | |
ChEBI | |
ChemSpider | |
DrugBank | |
KEGG | |
PubChem
CID
|
|
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C6H10O4 | |
Molar mass | 146.142 g·mol−1 |
Appearance | colorless or white |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Ketopantoic acid is the organic compound with the formula HOCH2(CH3)2CC(O)CO2H. At physiological conditions, ketopantoic acid exists as its conjugate base, ketopantoate (HOCH2(CH3)2CC(O)CO2−).
Its biosynthesis proceeds from ketoisovalerate by hydroxymethylation:
This conversion is catalyzed by ketopantoate hydroxymethyltransferase, which gives ketopantoate.
Ketopantoate is substrate for 2-dehydropantoate 2-reductase, [1] which produces pantoate, a precursor to pantothenic acid, a common prosthetic group. [2]