From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
PCLAF Available structures
PDB Ortholog search:
PDBe
RCSB List of PDB id codes
4D2G
Identifiers
Aliases
PCLAF , L5, NS5ATP9, OEATC, OEATC-1, OEATC1, PAF, PAF15, p15(PAF), p15/PAF, p15PAF, KIAA0101, PCNA clamp associated factorExternal IDs
OMIM :
610696 ;
MGI :
1915276 ;
HomoloGene :
8829 ;
GeneCards :
PCLAF ;
OMA :
PCLAF - orthologs
Wikidata
PCNA-associated factor is a
protein that in humans is encoded by the KIAA0101
gene .
[5]
[6]
[7]
KIAA0101 has been shown to
interact with
PCNA .
[5]
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000166803 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000040204 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
a
b Yu P, Huang B, Shen M, Lau C, Chan E, Michel J, Xiong Y, Payan DG, Luo Y (Jan 2001).
"p15(PAF), a novel PCNA associated factor with increased expression in tumor tissues" . Oncogene . 20 (4): 484–9.
doi :
10.1038/sj.onc.1204113 .
PMID
11313979 .
^ Simpson F, Lammerts van Bueren K, Butterfield N, Bennetts JS, Bowles J, Adolphe C, Simms LA, Young J, Walsh MD, Leggett B, Fowles LF, Wicking C (Jan 2006). "The PCNA-associated factor KIAA0101/p15(PAF) binds the potential tumor suppressor product p33ING1b". Experimental Cell Research . 312 (1): 73–85.
doi :
10.1016/j.yexcr.2005.09.020 .
PMID
16288740 .
^
"Entrez Gene: KIAA0101 KIAA0101" .
Shi L, Zhang SL, Li K, Hong Y, Wang Q, Li Y, Guo J, Fan WH, Zhang L, Cheng J (Feb 2008). "NS5ATP9, a gene up-regulated by HCV NS5A protein". Cancer Letters . 259 (2): 192–7.
doi :
10.1016/j.canlet.2007.10.029 .
PMID
18068894 .
Guo M, Li J, Wan D, Gu J (2006).
"KIAA0101 (OEACT-1), an expressionally down-regulated and growth-inhibitory gene in human hepatocellular carcinoma" . BMC Cancer . 6 : 109.
doi :
10.1186/1471-2407-6-109 .
PMC
1483895 .
PMID
16646990 .
Mizutani K, Onda M, Asaka S, Akaishi J, Miyamoto S, Yoshida A, Nagahama M, Ito K, Emi M (May 2005).
"Overexpressed in anaplastic thyroid carcinoma-1 (OEATC-1) as a novel gene responsible for anaplastic thyroid carcinoma" . Cancer . 103 (9): 1785–90.
doi :
10.1002/cncr.20988 .
PMID
15789362 .
Petroziello J, Yamane A, Westendorf L, Thompson M, McDonagh C, Cerveny C, Law CL, Wahl A, Carter P (Oct 2004).
"Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer" . Oncogene . 23 (46): 7734–45.
doi :
10.1038/sj.onc.1207921 .
PMID
15334068 .
Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H (1995).
"Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1" . DNA Research . 2 (1): 37–43.
doi :
10.1093/dnares/2.1.37 .
PMID
7788527 .