Katanin p60 ATPase-containing subunit A1 is an
enzyme that in humans is encoded by the KATNA1gene.[5][6]
Microtubules, polymers of alpha and beta
tubulin subunits, form the
mitotic spindle of a dividing cell and help to organize membranous organelles during
interphase.
Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the
AAA family of ATPases.[6]
Katanin p60 ATPase-containing subunit A1 is an
enzyme that in humans is encoded by the KATNA1gene.[5][6]
Microtubules, polymers of alpha and beta
tubulin subunits, form the
mitotic spindle of a dividing cell and help to organize membranous organelles during
interphase.
Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1). The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the
AAA family of ATPases.[6]