Junctional complexes between the
plasma membrane and endoplasmic/
sarcoplasmic reticulum are a common feature of all excitable
cell types and mediate cross talk between cell surface and intracellular
ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining
cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family.[7]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Nishi M, Mizushima A, Nakagawara K, Takeshima H (Sep 2000). "Characterization of human junctophilin subtype genes". Biochem Biophys Res Commun. 273 (3): 920–7.
doi:
10.1006/bbrc.2000.3011.
PMID10891348.
Junctional complexes between the
plasma membrane and endoplasmic/
sarcoplasmic reticulum are a common feature of all excitable
cell types and mediate cross talk between cell surface and intracellular
ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining
cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family.[7]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Nishi M, Mizushima A, Nakagawara K, Takeshima H (Sep 2000). "Characterization of human junctophilin subtype genes". Biochem Biophys Res Commun. 273 (3): 920–7.
doi:
10.1006/bbrc.2000.3011.
PMID10891348.