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From Wikipedia, the free encyclopedia
Jennifer Sue Brodbelt
Alma mater Purdue University
Known for Mass Spectrometry
AwardsField and Franklin Award
Scientific career
Fields Analytical Chemistry, Mass Spectrometry
Institutions Purdue University, University of California, Santa Barbara, University of Texas at Austin
Thesis Aspects of ion chemistry in mass spectrometry (1988)
Doctoral advisor R. Graham Cooks
Website http://brodbelt.cm.utexas.edu/research/

Jennifer S. Brodbelt is an American chemist known for her research using mass spectrometry to characterize organic compounds, especially biopolymers and proteins.

Education and career

Brodbelt has an undergraduate degree from the University of Virginia and earned her Ph.D. from Purdue University where she worked on gas phase ion chemistry using mass spectrometry. [1] Following her Ph.D. she was a postdoc at the University of California, Santa Barbara [2] before joining the University of Texas at Austin in 1989. [3] As of 2016, she is the Roland Pettit Centennial Chair in the Department of Chemistry. [4] [5]

She was the president of the American Society for Mass Spectrometry for the period of 2014–2016. [6]

Research

Brodbelt's research centers on the development of mass spectrometry-based methods to characterize organic molecules. [7] [8] Brodbelt's early research established methods to use chemical ionization in ion trap mass spectrometers [9] [10] and applied this method to the analysis of petroleum samples. [11] She subsequently worked on gas-phase ion chemistry [12] and photodissociation [13] as methods to break apart organic compounds before they are analyzed by a mass spectrometer. Her work has led to the analysis of compounds including recreational drugs, [14] [15] sunscreen, [16] and pesticides. [17] Her work also includes investigations into proteins [18] and other organic compounds produced by bacteria including [19] [20]

Selected publications

  • Brodbelt, Jennifer S. (24 March 2014). "Photodissociation mass spectrometry: new tools for characterization of biological molecules". Chemical Society Reviews. 43 (8): 2757–2783. doi: 10.1039/C3CS60444F. ISSN  1460-4744. PMC  3966968. PMID  24481009.
  • Shaw, Jared B.; Li, Wenzong; Holden, Dustin D.; Zhang, Yan; Griep-Raming, Jens; Fellers, Ryan T.; Early, Bryan P.; Thomas, Paul M.; Kelleher, Neil L.; Brodbelt, Jennifer S. (28 August 2013). "Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation". Journal of the American Chemical Society. 135 (34): 12646–12651. doi: 10.1021/ja4029654. PMC  3757099. PMID  23697802.
  • Kempen, Esther C.; Brodbelt, Jennifer S. (1 November 2000). "A Method for the Determination of Binding Constants by Electrospray Ionization Mass Spectrometry". Analytical Chemistry. 72 (21): 5411–5416. doi: 10.1021/ac000540e. ISSN  0003-2700. PMID  11080894.

Awards

She was awarded the Agnes Fay Morgan Research Award in 1995. [21] In 2019, Brodbelt received the Frank H. Field and Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry from the American Chemical Society. [22] In 2023, she was named one of the "Mentors and Educators" in the Power List by the Analytical Scientist. [23]

References

  1. ^ Brodbelt-Lustig, Jennifer Sue (1998). Aspects of ion chemistry in mass spectrometry (Ph.D.). Retrieved October 6, 2021.
  2. ^ Brodbelt, Jennifer. "Postdoctoral Research Fellowship in Chemistry". {{ cite journal}}: Cite journal requires |journal= ( help)
  3. ^ "Jennifer S. Brodbelt - Professor of Biochemistry and Molecular Genetics in Austin, Texas, United States Of America | eMedEvents". eMedEvents.com. Retrieved 2021-10-06.
  4. ^ "Faculty". utexas.edu. Retrieved December 13, 2016.
  5. ^ "Jennifer Brodbelt". utexas.edu. Retrieved December 13, 2016.
  6. ^ "Past Presidents". Retrieved 2019-04-19.
  7. ^ Brodbelt, Jennifer S. (1997). "Analytical applications of ion-molecule reactions". Mass Spectrometry Reviews. 16 (2): 91–110. Bibcode: 1997MSRv...16...91B. doi: 10.1002/(SICI)1098-2787(1997)16:2<91::AID-MAS3>3.0.CO;2-4. ISSN  1098-2787.
  8. ^ "Jennifer Brodbelt". The Analytical Scientist. 2019. Retrieved 2021-10-06.
  9. ^ Brodbelt, Jennifer S.; Louris, John N.; Cooks, R. Graham. (1987-05-01). "Chemical ionization in an ion trap mass spectrometer". Analytical Chemistry. 59 (9): 1278–1285. doi: 10.1021/ac00136a007. ISSN  0003-2700.
  10. ^ Brodbelt, Jennifer.; Liou, Chien Chung.; Donovan, Tracy. (1991-07-01). "Selective adduct formation by dimethyl ether chemical ionization in a quadrupole ion trap mass spectrometer and a conventional ion source". Analytical Chemistry. 63 (13): 1205–1209. doi: 10.1021/ac00013a005. ISSN  0003-2700.
  11. ^ Brodbelt, Jennifer S.; Cooks, R. Graham; Wood, Karl V.; Jackson, Thomas J. (1986-01-01). "The Analysis of Metalloporphyrins in Petroleum Using Tandem Mass Spectrometry". Fuel Science and Technology International. 4 (6): 683–698. Bibcode: 1986FSTI....4..683B. doi: 10.1080/08843758608915836. ISSN  0884-3759.
  12. ^ Brodbelt, J. S.; Liou, C.-C. (1993-01-01). "New frontiers in host-guest chemistry: The gas phase". Pure and Applied Chemistry (in German). 65 (3): 409–414. doi: 10.1351/pac199365030409. ISSN  1365-3075. S2CID  31322707.
  13. ^ Brodbelt, Jennifer S.; Wilson, Jeffrey J. (2009). "Infrared multiphoton dissociation in quadrupole ion traps". Mass Spectrometry Reviews. 28 (3): 390–424. Bibcode: 2009MSRv...28..390B. doi: 10.1002/mas.20216. ISSN  1098-2787. PMID  19294735.
  14. ^ Hall, Brad J; Brodbelt, Jennifer S (1997-08-15). "Determination of barbiturates by solid-phase microextraction (SPME) and ion trap gas chromatography–mass spectrometry". Journal of Chromatography A. 777 (2): 275–282. doi: 10.1016/S0021-9673(97)00363-4. ISSN  0021-9673. PMID  9299725.
  15. ^ Hall, Brad J.; Satterfield-Doerr, Mary; Parikh, Aashish R.; Brodbelt, Jennifer S. (1998-05-01). "Determination of Cannabinoids in Water and Human Saliva by Solid-Phase Microextraction and Quadrupole Ion Trap Gas Chromatography/Mass Spectrometry". Analytical Chemistry. 70 (9): 1788–1796. doi: 10.1021/ac971228g. ISSN  0003-2700. PMID  9599579.
  16. ^ Felix, Tonya; Hall, Brad J; S. Brodbelt, Jennifer (1998-10-05). "Determination of benzophenone-3 and metabolites in water and human urine by solid-phase microextraction and quadrupole ion trap GC–MS". Analytica Chimica Acta. 371 (2): 195–203. Bibcode: 1998AcAC..371..195F. doi: 10.1016/S0003-2670(98)00293-1. ISSN  0003-2670.
  17. ^ Reyzer, Michelle L; Brodbelt, Jennifer S (2001-06-01). "Analysis of fire ant pesticides in water by solid-phase microextraction and gas chromatography/mass spectrometry or high-performance liquid chromatography/mass spectrometry". Analytica Chimica Acta. 436 (1): 11–20. Bibcode: 2001AcAC..436...11R. doi: 10.1016/S0003-2670(01)00893-5. ISSN  0003-2670.
  18. ^ Shaw, Jared B.; Li, Wenzong; Holden, Dustin D.; Zhang, Yan; Griep-Raming, Jens; Fellers, Ryan T.; Early, Bryan P.; Thomas, Paul M.; Kelleher, Neil L.; Brodbelt, Jennifer S. (2013-08-28). "Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation". Journal of the American Chemical Society. 135 (34): 12646–12651. doi: 10.1021/ja4029654. ISSN  0002-7863. PMC  3757099. PMID  23697802.
  19. ^ Hankins, Jessica V.; Madsen, James A.; Giles, David K.; Brodbelt, Jennifer S.; Trent, M. Stephen (2012-05-29). "Amino acid addition to Vibrio cholerae LPS establishes a link between surface remodeling in Gram-positive and Gram-negative bacteria". Proceedings of the National Academy of Sciences. 109 (22): 8722–8727. Bibcode: 2012PNAS..109.8722H. doi: 10.1073/pnas.1201313109. ISSN  0027-8424. PMC  3365186. PMID  22589301.
  20. ^ Han, Sang-Wook; Lee, Sang-Won; Bahar, Ofir; Schwessinger, Benjamin; Robinson, Michelle R.; Shaw, Jared B.; Madsen, James A.; Brodbelt, Jennifer S.; Ronald, Pamela C. (2012). "Tyrosine sulfation in a Gram-negative bacterium". Nature Communications. 3 (1): 1153. Bibcode: 2012NatCo...3.1153H. doi: 10.1038/ncomms2157. ISSN  2041-1723. PMC  4305400. PMID  23093190.
  21. ^ "Past Award Winners | Iota Sigma Pi". 2021-10-06. Archived from the original on 2021-10-06. Retrieved 2021-10-06.
  22. ^ "Frank H. Field & Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry: Vicki H. Wysocki". C&EN Global Enterprise. 95 (1): 49–50. 2017-01-02. doi: 10.1021/cen-09501-awards054. ISSN  2474-7408.
  23. ^ "The Power List 2023". The Analytical Scientist. 2023-09-10. Retrieved 2023-09-02.

External links

Retrieved from " https://en.wikipedia.org/?title=Jennifer_S._Brodbelt&oldid=1207432799"
From Wikipedia, the free encyclopedia
Jennifer Sue Brodbelt
Alma mater Purdue University
Known for Mass Spectrometry
AwardsField and Franklin Award
Scientific career
Fields Analytical Chemistry, Mass Spectrometry
Institutions Purdue University, University of California, Santa Barbara, University of Texas at Austin
Thesis Aspects of ion chemistry in mass spectrometry (1988)
Doctoral advisor R. Graham Cooks
Website http://brodbelt.cm.utexas.edu/research/

Jennifer S. Brodbelt is an American chemist known for her research using mass spectrometry to characterize organic compounds, especially biopolymers and proteins.

Education and career

Brodbelt has an undergraduate degree from the University of Virginia and earned her Ph.D. from Purdue University where she worked on gas phase ion chemistry using mass spectrometry. [1] Following her Ph.D. she was a postdoc at the University of California, Santa Barbara [2] before joining the University of Texas at Austin in 1989. [3] As of 2016, she is the Roland Pettit Centennial Chair in the Department of Chemistry. [4] [5]

She was the president of the American Society for Mass Spectrometry for the period of 2014–2016. [6]

Research

Brodbelt's research centers on the development of mass spectrometry-based methods to characterize organic molecules. [7] [8] Brodbelt's early research established methods to use chemical ionization in ion trap mass spectrometers [9] [10] and applied this method to the analysis of petroleum samples. [11] She subsequently worked on gas-phase ion chemistry [12] and photodissociation [13] as methods to break apart organic compounds before they are analyzed by a mass spectrometer. Her work has led to the analysis of compounds including recreational drugs, [14] [15] sunscreen, [16] and pesticides. [17] Her work also includes investigations into proteins [18] and other organic compounds produced by bacteria including [19] [20]

Selected publications

  • Brodbelt, Jennifer S. (24 March 2014). "Photodissociation mass spectrometry: new tools for characterization of biological molecules". Chemical Society Reviews. 43 (8): 2757–2783. doi: 10.1039/C3CS60444F. ISSN  1460-4744. PMC  3966968. PMID  24481009.
  • Shaw, Jared B.; Li, Wenzong; Holden, Dustin D.; Zhang, Yan; Griep-Raming, Jens; Fellers, Ryan T.; Early, Bryan P.; Thomas, Paul M.; Kelleher, Neil L.; Brodbelt, Jennifer S. (28 August 2013). "Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation". Journal of the American Chemical Society. 135 (34): 12646–12651. doi: 10.1021/ja4029654. PMC  3757099. PMID  23697802.
  • Kempen, Esther C.; Brodbelt, Jennifer S. (1 November 2000). "A Method for the Determination of Binding Constants by Electrospray Ionization Mass Spectrometry". Analytical Chemistry. 72 (21): 5411–5416. doi: 10.1021/ac000540e. ISSN  0003-2700. PMID  11080894.

Awards

She was awarded the Agnes Fay Morgan Research Award in 1995. [21] In 2019, Brodbelt received the Frank H. Field and Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry from the American Chemical Society. [22] In 2023, she was named one of the "Mentors and Educators" in the Power List by the Analytical Scientist. [23]

References

  1. ^ Brodbelt-Lustig, Jennifer Sue (1998). Aspects of ion chemistry in mass spectrometry (Ph.D.). Retrieved October 6, 2021.
  2. ^ Brodbelt, Jennifer. "Postdoctoral Research Fellowship in Chemistry". {{ cite journal}}: Cite journal requires |journal= ( help)
  3. ^ "Jennifer S. Brodbelt - Professor of Biochemistry and Molecular Genetics in Austin, Texas, United States Of America | eMedEvents". eMedEvents.com. Retrieved 2021-10-06.
  4. ^ "Faculty". utexas.edu. Retrieved December 13, 2016.
  5. ^ "Jennifer Brodbelt". utexas.edu. Retrieved December 13, 2016.
  6. ^ "Past Presidents". Retrieved 2019-04-19.
  7. ^ Brodbelt, Jennifer S. (1997). "Analytical applications of ion-molecule reactions". Mass Spectrometry Reviews. 16 (2): 91–110. Bibcode: 1997MSRv...16...91B. doi: 10.1002/(SICI)1098-2787(1997)16:2<91::AID-MAS3>3.0.CO;2-4. ISSN  1098-2787.
  8. ^ "Jennifer Brodbelt". The Analytical Scientist. 2019. Retrieved 2021-10-06.
  9. ^ Brodbelt, Jennifer S.; Louris, John N.; Cooks, R. Graham. (1987-05-01). "Chemical ionization in an ion trap mass spectrometer". Analytical Chemistry. 59 (9): 1278–1285. doi: 10.1021/ac00136a007. ISSN  0003-2700.
  10. ^ Brodbelt, Jennifer.; Liou, Chien Chung.; Donovan, Tracy. (1991-07-01). "Selective adduct formation by dimethyl ether chemical ionization in a quadrupole ion trap mass spectrometer and a conventional ion source". Analytical Chemistry. 63 (13): 1205–1209. doi: 10.1021/ac00013a005. ISSN  0003-2700.
  11. ^ Brodbelt, Jennifer S.; Cooks, R. Graham; Wood, Karl V.; Jackson, Thomas J. (1986-01-01). "The Analysis of Metalloporphyrins in Petroleum Using Tandem Mass Spectrometry". Fuel Science and Technology International. 4 (6): 683–698. Bibcode: 1986FSTI....4..683B. doi: 10.1080/08843758608915836. ISSN  0884-3759.
  12. ^ Brodbelt, J. S.; Liou, C.-C. (1993-01-01). "New frontiers in host-guest chemistry: The gas phase". Pure and Applied Chemistry (in German). 65 (3): 409–414. doi: 10.1351/pac199365030409. ISSN  1365-3075. S2CID  31322707.
  13. ^ Brodbelt, Jennifer S.; Wilson, Jeffrey J. (2009). "Infrared multiphoton dissociation in quadrupole ion traps". Mass Spectrometry Reviews. 28 (3): 390–424. Bibcode: 2009MSRv...28..390B. doi: 10.1002/mas.20216. ISSN  1098-2787. PMID  19294735.
  14. ^ Hall, Brad J; Brodbelt, Jennifer S (1997-08-15). "Determination of barbiturates by solid-phase microextraction (SPME) and ion trap gas chromatography–mass spectrometry". Journal of Chromatography A. 777 (2): 275–282. doi: 10.1016/S0021-9673(97)00363-4. ISSN  0021-9673. PMID  9299725.
  15. ^ Hall, Brad J.; Satterfield-Doerr, Mary; Parikh, Aashish R.; Brodbelt, Jennifer S. (1998-05-01). "Determination of Cannabinoids in Water and Human Saliva by Solid-Phase Microextraction and Quadrupole Ion Trap Gas Chromatography/Mass Spectrometry". Analytical Chemistry. 70 (9): 1788–1796. doi: 10.1021/ac971228g. ISSN  0003-2700. PMID  9599579.
  16. ^ Felix, Tonya; Hall, Brad J; S. Brodbelt, Jennifer (1998-10-05). "Determination of benzophenone-3 and metabolites in water and human urine by solid-phase microextraction and quadrupole ion trap GC–MS". Analytica Chimica Acta. 371 (2): 195–203. Bibcode: 1998AcAC..371..195F. doi: 10.1016/S0003-2670(98)00293-1. ISSN  0003-2670.
  17. ^ Reyzer, Michelle L; Brodbelt, Jennifer S (2001-06-01). "Analysis of fire ant pesticides in water by solid-phase microextraction and gas chromatography/mass spectrometry or high-performance liquid chromatography/mass spectrometry". Analytica Chimica Acta. 436 (1): 11–20. Bibcode: 2001AcAC..436...11R. doi: 10.1016/S0003-2670(01)00893-5. ISSN  0003-2670.
  18. ^ Shaw, Jared B.; Li, Wenzong; Holden, Dustin D.; Zhang, Yan; Griep-Raming, Jens; Fellers, Ryan T.; Early, Bryan P.; Thomas, Paul M.; Kelleher, Neil L.; Brodbelt, Jennifer S. (2013-08-28). "Complete Protein Characterization Using Top-Down Mass Spectrometry and Ultraviolet Photodissociation". Journal of the American Chemical Society. 135 (34): 12646–12651. doi: 10.1021/ja4029654. ISSN  0002-7863. PMC  3757099. PMID  23697802.
  19. ^ Hankins, Jessica V.; Madsen, James A.; Giles, David K.; Brodbelt, Jennifer S.; Trent, M. Stephen (2012-05-29). "Amino acid addition to Vibrio cholerae LPS establishes a link between surface remodeling in Gram-positive and Gram-negative bacteria". Proceedings of the National Academy of Sciences. 109 (22): 8722–8727. Bibcode: 2012PNAS..109.8722H. doi: 10.1073/pnas.1201313109. ISSN  0027-8424. PMC  3365186. PMID  22589301.
  20. ^ Han, Sang-Wook; Lee, Sang-Won; Bahar, Ofir; Schwessinger, Benjamin; Robinson, Michelle R.; Shaw, Jared B.; Madsen, James A.; Brodbelt, Jennifer S.; Ronald, Pamela C. (2012). "Tyrosine sulfation in a Gram-negative bacterium". Nature Communications. 3 (1): 1153. Bibcode: 2012NatCo...3.1153H. doi: 10.1038/ncomms2157. ISSN  2041-1723. PMC  4305400. PMID  23093190.
  21. ^ "Past Award Winners | Iota Sigma Pi". 2021-10-06. Archived from the original on 2021-10-06. Retrieved 2021-10-06.
  22. ^ "Frank H. Field & Joe L. Franklin Award for Outstanding Achievement in Mass Spectrometry: Vicki H. Wysocki". C&EN Global Enterprise. 95 (1): 49–50. 2017-01-02. doi: 10.1021/cen-09501-awards054. ISSN  2474-7408.
  23. ^ "The Power List 2023". The Analytical Scientist. 2023-09-10. Retrieved 2023-09-02.

External links

Retrieved from " https://en.wikipedia.org/?title=Jennifer_S._Brodbelt&oldid=1207432799"

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