| Monoclonal antibody | |
|---|---|
| Type | Fab' fragment |
| Source | Mouse |
| Target | Fibrin II, beta chain |
| Clinical data | |
| Trade names | FibriScint |
|
Pregnancy category |
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| ATC code |
|
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | |
| ChemSpider |
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| KEGG | |
 
(what is this?)
(verify) | |
Indium (111In) biciromab ( INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood. [1] It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism, [2] but was withdrawn during clinical trials. [3]
References
- ^ King DJ, Adair JR (March 1999). "Recombinant antibodies for the diagnosis and therapy of human diseases". Current Opinion in Drug Discovery & Development. 2 (2): 110–7. PMID 19649936.
- ^ "Centocor Ortho Biotech Products, L.P." Answers.com.
- ^ "Centocor withdraws imaging agent applications". DiagnosticImaging.com.
 | This monoclonal antibody–related article is a stub. You can help Wikipedia by expanding it. |
| Monoclonal antibody | |
|---|---|
| Type | Fab' fragment |
| Source | Mouse |
| Target | Fibrin II, beta chain |
| Clinical data | |
| Trade names | FibriScint |
|
Pregnancy category |
|
| ATC code |
|
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | |
| ChemSpider |
|
| KEGG | |
|
(what is this?)
(verify) | |
Indium (111In) biciromab ( INN, trade name FibriScint, developed by Centocor) was a drug targeting fibrin, a protein involved in the clotting of blood. [1] It was the Fab' fragment of a mouse monoclonal antibody labelled with the radioisotope indium-111 for the diagnosis of thromboembolism, [2] but was withdrawn during clinical trials. [3]
References
- ^ King DJ, Adair JR (March 1999). "Recombinant antibodies for the diagnosis and therapy of human diseases". Current Opinion in Drug Discovery & Development. 2 (2): 110–7. PMID 19649936.
- ^ "Centocor Ortho Biotech Products, L.P." Answers.com.
- ^ "Centocor withdraws imaging agent applications". DiagnosticImaging.com.
|
| This monoclonal antibody–related article is a stub. You can help Wikipedia by expanding it. |