Impetigo herpetiformis | |
---|---|
Other names | Pustular psoriasis of pregnancy |
Specialty |
Dermatology,
obstetrics
![]() |
Impetigo herpetiformis is a form of severe pustular psoriasis occurring in pregnancy [1] [2] which may occur during any trimester. [3] [4]
The typical lesions are centrifugally extending erythematous patches with marginally grouped sterile pustules; they can also develop erosion, crust, and impetiginization. These lesions are mainly seen in flexural regions. Patients may experience vegetative lesions resembling Pemphigus vegetans, though they are uncommon. [5] It is possible to see mucosal lesions in the tongue, mouth, and even esophagus in addition to nail involvement. [6]
In impetigo herpetiformis, hypoparathyroidism and hypocalcemia may be encountered. [7] Systematic symptoms such as malaise, hypovolemic shock, vomiting, chills, fever, diarrhea, and seizures may also be seen. [8]
The cause of impetigo herpetiformis is not yet clear. [8] Some evidence suggests that genetic factors may play a role in the development of impetigo herpetiformis, such as the number of familial cases. [9]
The diagnosis of impetigo herpetiformis is supported by clinical and laboratory findings, and histological examination primarily reveals neutrophilc inflammatory infiltrate, epidermal acanthosis, and papillomatosis with focal parakeratosis. [10] Spongiform pustules of Kogoj are intraepidermal multilocular microabscesses that are formed by neutrophil collections. [11]
Laboratory findings include iron deficiency anemia, hypoalbuminemia, hypocalcemia, elevated erythrocyte sedimentation rate, and leukocytosis. [12]
Pustular psoriasis is still primarily treated with systemic corticosteroids, which have been used for many years. [13] If a patient is not responding to corticosteroids, cyclosporine may be a useful medication. [14] In impetigo herpetiformis, the use of antibiotics appears to be beneficial, despite the fact that they cannot completely eradicate the illness. [15] [16]
Impetigo herpetiformis | |
---|---|
Other names | Pustular psoriasis of pregnancy |
Specialty |
Dermatology,
obstetrics
![]() |
Impetigo herpetiformis is a form of severe pustular psoriasis occurring in pregnancy [1] [2] which may occur during any trimester. [3] [4]
The typical lesions are centrifugally extending erythematous patches with marginally grouped sterile pustules; they can also develop erosion, crust, and impetiginization. These lesions are mainly seen in flexural regions. Patients may experience vegetative lesions resembling Pemphigus vegetans, though they are uncommon. [5] It is possible to see mucosal lesions in the tongue, mouth, and even esophagus in addition to nail involvement. [6]
In impetigo herpetiformis, hypoparathyroidism and hypocalcemia may be encountered. [7] Systematic symptoms such as malaise, hypovolemic shock, vomiting, chills, fever, diarrhea, and seizures may also be seen. [8]
The cause of impetigo herpetiformis is not yet clear. [8] Some evidence suggests that genetic factors may play a role in the development of impetigo herpetiformis, such as the number of familial cases. [9]
The diagnosis of impetigo herpetiformis is supported by clinical and laboratory findings, and histological examination primarily reveals neutrophilc inflammatory infiltrate, epidermal acanthosis, and papillomatosis with focal parakeratosis. [10] Spongiform pustules of Kogoj are intraepidermal multilocular microabscesses that are formed by neutrophil collections. [11]
Laboratory findings include iron deficiency anemia, hypoalbuminemia, hypocalcemia, elevated erythrocyte sedimentation rate, and leukocytosis. [12]
Pustular psoriasis is still primarily treated with systemic corticosteroids, which have been used for many years. [13] If a patient is not responding to corticosteroids, cyclosporine may be a useful medication. [14] In impetigo herpetiformis, the use of antibiotics appears to be beneficial, despite the fact that they cannot completely eradicate the illness. [15] [16]