Imjin thottimvirus | |
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Virus classification
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(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Negarnaviricota |
Class: | Ellioviricetes |
Order: | Bunyavirales |
Family: | Hantaviridae |
Genus: | Thottimvirus |
Species: | Imjin thottimvirus
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Synonyms [1] | |
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Imjin thottimvirus (MJNV) is a single-stranded, enveloped, negative-sense RNA virus of the orthohantavirus genus in the Bunyavirales order. It is a newly identified hantavirus isolated from the lung tissues of Ussuri white-toothed shrews of the species Crocidura lasiura (order Soricomorpha, family Soricidae, subfamily Crocidurinae) captured near the demilitarized zone in the Republic of Korea during 2004 and 2005.
Phylogenetic analyses demonstrates a common ancestry with Thottopalayam thottimvirus suggesting early evolutionary divergence. It is still unknown if MJNV is pathogenic for humans. [2]
MJNV has been shown to be a genetically unique hantavirus. Multiple strains have been isolated from the lung tissues of Ussuri white-toothed shrews captured between 2004 and 2010. Partial M- and L-segment sequences from lung tissues of 12 of 37 (32.4%) anti-MJNV IgG antibody-positive shrews revealed that the 12 MJNV strains differed by 0–12.2% and 0–2.3% at the nucleotide and amino acid levels. A similar degree of nucleotide and amino acid difference was found in a 632-nucleotide length of the L segment of nine MJNV strains. Phylogenetic analyses demonstrated a geographic relationship similar to the phylogeography of rodent-borne hantaviruses. [3]
Imjin thottimvirus | |
---|---|
Virus classification
![]() | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Negarnaviricota |
Class: | Ellioviricetes |
Order: | Bunyavirales |
Family: | Hantaviridae |
Genus: | Thottimvirus |
Species: | Imjin thottimvirus
|
Synonyms [1] | |
|
Imjin thottimvirus (MJNV) is a single-stranded, enveloped, negative-sense RNA virus of the orthohantavirus genus in the Bunyavirales order. It is a newly identified hantavirus isolated from the lung tissues of Ussuri white-toothed shrews of the species Crocidura lasiura (order Soricomorpha, family Soricidae, subfamily Crocidurinae) captured near the demilitarized zone in the Republic of Korea during 2004 and 2005.
Phylogenetic analyses demonstrates a common ancestry with Thottopalayam thottimvirus suggesting early evolutionary divergence. It is still unknown if MJNV is pathogenic for humans. [2]
MJNV has been shown to be a genetically unique hantavirus. Multiple strains have been isolated from the lung tissues of Ussuri white-toothed shrews captured between 2004 and 2010. Partial M- and L-segment sequences from lung tissues of 12 of 37 (32.4%) anti-MJNV IgG antibody-positive shrews revealed that the 12 MJNV strains differed by 0–12.2% and 0–2.3% at the nucleotide and amino acid levels. A similar degree of nucleotide and amino acid difference was found in a 632-nucleotide length of the L segment of nine MJNV strains. Phylogenetic analyses demonstrated a geographic relationship similar to the phylogeography of rodent-borne hantaviruses. [3]