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Organisms | Human |
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The Human Cell Atlas is a project to describe all cell types in the human body. The initiative was announced by a consortium after its inaugural meeting in London in October 2016, which established the first phase of the project. [1] [2] Aviv Regev and Sarah Teichmann defined the goals of the project at that meeting, [3] which was convened by the Broad Institute, the Wellcome Trust Sanger Institute and Wellcome Trust. [4] Regev and Teichmann lead the project. [5]
The Human Cell Atlas will catalogue a cell based on several criteria, specifically the cell type, its state, its location in the body, the transitions it undergoes, and its lineage. [6] It will gather data from existing research, and integrate it with data collected in future research projects. [2] Among the data it will collect is the fluxome, genome, metabolome, proteome, and transcriptome. [2]
Its scope is to categorize the 37 trillion cells of the human body to determine which genes each cell expresses by sampling cells from all parts of the body. [7]
All aspects of the project will be made "available to the public for free", including software and results. [8]
By April 2018, the project included more than 480 researchers conducting 185 projects. [9]
In October 2017, the Chan Zuckerberg Initiative announced funding for 38 projects related to the Human Cell Atlas. [10] Among them was a grant of undisclosed value to the Zuckerman Institute of the Columbia University Medical Center at Columbia University. [8] The grant, titled "A strategy for mapping the human spinal cord with single cell resolution", will fund research to identify and catalogue gene activity in all spinal cord cells. [8] The Translational Genomics Research Institute received a grant to develop a standard for the "processing and storage of solid tissues for single-cell RNA sequencing", compared to the typical practice of relying on the average of sequencing multiple cells. [10] Project home pages are available at the Chan Zuckerberg Initiative's website. [11]
The program is also backed by European Union, the National Institutes of Health in the United States, and the Manton Foundation. [7]
In April 2018, the first data set from the project was released, representing 530,000 immune system cells collected from bone marrow and cord blood. [9]
A research program at the Max Planck Institute of Immunobiology and Epigenetics published an atlas of the cells of the liver, using single-cell RNA sequencing on 10,000 normal cells obtained from nine donors. [12]
The Tabula Sapiens data was published on a dedicated website [13]
Content | |
---|---|
Organisms | Human |
Access | |
Website |
www |
The Human Cell Atlas is a project to describe all cell types in the human body. The initiative was announced by a consortium after its inaugural meeting in London in October 2016, which established the first phase of the project. [1] [2] Aviv Regev and Sarah Teichmann defined the goals of the project at that meeting, [3] which was convened by the Broad Institute, the Wellcome Trust Sanger Institute and Wellcome Trust. [4] Regev and Teichmann lead the project. [5]
The Human Cell Atlas will catalogue a cell based on several criteria, specifically the cell type, its state, its location in the body, the transitions it undergoes, and its lineage. [6] It will gather data from existing research, and integrate it with data collected in future research projects. [2] Among the data it will collect is the fluxome, genome, metabolome, proteome, and transcriptome. [2]
Its scope is to categorize the 37 trillion cells of the human body to determine which genes each cell expresses by sampling cells from all parts of the body. [7]
All aspects of the project will be made "available to the public for free", including software and results. [8]
By April 2018, the project included more than 480 researchers conducting 185 projects. [9]
In October 2017, the Chan Zuckerberg Initiative announced funding for 38 projects related to the Human Cell Atlas. [10] Among them was a grant of undisclosed value to the Zuckerman Institute of the Columbia University Medical Center at Columbia University. [8] The grant, titled "A strategy for mapping the human spinal cord with single cell resolution", will fund research to identify and catalogue gene activity in all spinal cord cells. [8] The Translational Genomics Research Institute received a grant to develop a standard for the "processing and storage of solid tissues for single-cell RNA sequencing", compared to the typical practice of relying on the average of sequencing multiple cells. [10] Project home pages are available at the Chan Zuckerberg Initiative's website. [11]
The program is also backed by European Union, the National Institutes of Health in the United States, and the Manton Foundation. [7]
In April 2018, the first data set from the project was released, representing 530,000 immune system cells collected from bone marrow and cord blood. [9]
A research program at the Max Planck Institute of Immunobiology and Epigenetics published an atlas of the cells of the liver, using single-cell RNA sequencing on 10,000 normal cells obtained from nine donors. [12]
The Tabula Sapiens data was published on a dedicated website [13]