Goethe University Frankfurt: chemistry and biochemistry (1961–1967); doctorate in biochemistry and pharmacy (1972); postdoctoral qualification in human medicine for the subject of experimental endocrinology (1977)[1]
Among Kuhl's most widely cited publications is his 2005
literature review in the journal Climacteric, Pharmacology of Estrogens and Progestogens: Influence of Different Routes of Administration.[3][4] He has published several articles interpreting the findings of the
Women's Health Initiative (WHI) study.[5][6][7][8][9][10][11]
Kuhl was born in
Aschaffenburg, Germany in 1940.[1] He was educated at the
Goethe University Frankfurt from 1961 to 1977.[1] Kuhl first published in 1970.[2] From 1981, he was a professor at the Universitäts-Frauenklinik (University Women's Clinic) of the Goethe University Frankfurt.[5] Until 2013, Kuhl continued to be affiliated with this institution.[11] Since then however, he has listed no affiliation in his publications except that he resides in Aschaffenburg, Germany.[12][13]
Selected publications
Books
Authored books
Kuhl, Herbert; Taubert, Hans-Dieter (1987). Das Klimakterium – Pathophysiologie, Klinik, Therapie [The Climacteric – Pathophysiology, Clinic, Therapy] (in German). Stuttgart, Germany:
Thieme Verlag.
ISBN978-3137008019.
OCLC19780387.
OL31949169M. (1st and only edition)
Herbert Kuhl; Claudia Jung-Hoffman (1999). Kontrazeption [Contraception] (in German) (2 ed.). Georg Thieme Verlag.
ISBN978-3131179920.
OCLC237359985.
OL12671120M. (1st edition published in 1996)
Kuhl, H. (1999). "Hormonal Contraception". In Oettel, M.; Schillinger, E. (eds.). Estrogens and Antiestrogens II: Pharmacology and Clinical Application of Estrogens and Antiestrogens. Handbook of Experimental Pharmacology. Vol. 135 / 2. Berlin/Heidelberg: Springer. pp. 363–407.
doi:
10.1007/978-3-642-60107-1_18.
eISSN1865-0325.
ISBN978-3-642-64261-6.
ISSN0171-2004.
Kuhl H (December 1986). "Hormonsubstitution durch Injektionspräparate und Hautimplantate" [Hormone substitution by injectable preparations and skin implants]. Der Gynäkologe (in German). 19 (4): 241–247.
PMID3817596.
Kuhl, H. (December 1990). "Ovulationshemmer: Die Bedeutung der Östrogendosis" [Ovulation Preventives: The Significance of the Estrogen Dose]. Geburtshilfe und Frauenheilkunde (in German). 50 (12): 910–922.
doi:
10.1055/s-2008-1026392.
eISSN1438-8804.
ISSN0016-5751.
PMID2086334.
Kuhl, H. (18 April 1997). "Metabolische Effekte der Östrogene und Gestagene" [Metabolic effects of estrogens and progestogens]. Der Gynäkologe (in German). 30 (4): 357–369.
doi:
10.1007/PL00003042.
ISSN0017-5994.
S2CID43381309.
Kuhl, H.; Wiegratz, I. (1 February 2021). "Pharmakokinetik und Pharmakodynamik der in der assistierten Reproduktion verwendeten Gestagene" [Pharmacokinetics and pharmacodynamics of progestogens used in assisted reproduction]. Gynäkologische Endokrinologie (in German). 19 (2): 105–117.
doi:
10.1007/s10304-020-00372-5.
eISSN1610-2908.
ISSN1610-2894.
S2CID231744549.
Studies
Wiegratz, I.; Jung-Hoffmann, C.; Kuhl, H. (June 1995). "Effect of two oral contraceptives containing ethinylestradiol and gestodene or norgestimate upon androgen parameters and serum binding proteins". Contraception. 51 (6): 341–346.
doi:
10.1016/0010-7824(95)00098-U.
ISSN0010-7824.
PMID7554973.
^
abTaubert, H.-D.; Heil, H.; Kuhl, H. (1970). "Untersuchungen über die Wirkung von Äthynil-Oestradiol auf die L-Cystin-Aminopeptidosen-Aktivität im Hypothalamus der weiblichen Ratte" [Investigations on the Effect of Ethynil-Oestradiol on L-Cystine-amino-peptidase Activity in the Hypothalamus of Female Rats]. In Kracht, Joachim (ed.).
Endokrinologie der Entwicklung und Reifung: 16. Symposion, Ulm, 26.-28. Februar 1970. Symposion der Deutschen Gesellschaft für Endokrinologie. Vol. 16. Berlin/Heidelberg/New York: Springer-Verlag. pp. 288–289.
doi:
10.1007/978-3-642-80591-2.
ISBN978-3-642-80591-2.
OCLC863921711.
^Mueck, A. O.; Kuhl, H.; Braendle, W. (September 2004). "Ergebnisse und Kommentare zu der WHI-Studie mit Estrogen-Monotherapie" [Results of and Comments on the WHI Study with Estrogen Monotherapy]. Geburtshilfe und Frauenheilkunde (in German). 64 (9): 917–922.
doi:
10.1055/s-2004-821217.
eISSN1438-8804.
ISSN0016-5751.
S2CID71579060.
^Kuhl H (September 2004). "Is the elevated breast cancer risk observed in the WHI study an artifact?". Climacteric. 7 (3): 319–22.
doi:
10.1080/13697130400003337.
PMID15669557.
^Kuhl H, Stevenson J (June 2006). "The effect of medroxyprogesterone acetate on estrogen-dependent risks and benefits--an attempt to interpret the Women's Health Initiative results". Gynecol Endocrinol. 22 (6): 303–17.
doi:
10.1080/09513590600717368.
PMID16785155.
S2CID25260381.
^Kuhl, H.; Wiegratz, I. (1 February 2021). "Pharmakokinetik und Pharmakodynamik der in der assistierten Reproduktion verwendeten Gestagene" [Pharmacokinetics and pharmacodynamics of progestogens used in assisted reproduction]. Gynäkologische Endokrinologie (in German). 19 (2): 105–117.
doi:
10.1007/s10304-020-00372-5.
eISSN1610-2908.
ISSN1610-2894.
S2CID231744549.
Goethe University Frankfurt: chemistry and biochemistry (1961–1967); doctorate in biochemistry and pharmacy (1972); postdoctoral qualification in human medicine for the subject of experimental endocrinology (1977)[1]
Among Kuhl's most widely cited publications is his 2005
literature review in the journal Climacteric, Pharmacology of Estrogens and Progestogens: Influence of Different Routes of Administration.[3][4] He has published several articles interpreting the findings of the
Women's Health Initiative (WHI) study.[5][6][7][8][9][10][11]
Kuhl was born in
Aschaffenburg, Germany in 1940.[1] He was educated at the
Goethe University Frankfurt from 1961 to 1977.[1] Kuhl first published in 1970.[2] From 1981, he was a professor at the Universitäts-Frauenklinik (University Women's Clinic) of the Goethe University Frankfurt.[5] Until 2013, Kuhl continued to be affiliated with this institution.[11] Since then however, he has listed no affiliation in his publications except that he resides in Aschaffenburg, Germany.[12][13]
Selected publications
Books
Authored books
Kuhl, Herbert; Taubert, Hans-Dieter (1987). Das Klimakterium – Pathophysiologie, Klinik, Therapie [The Climacteric – Pathophysiology, Clinic, Therapy] (in German). Stuttgart, Germany:
Thieme Verlag.
ISBN978-3137008019.
OCLC19780387.
OL31949169M. (1st and only edition)
Herbert Kuhl; Claudia Jung-Hoffman (1999). Kontrazeption [Contraception] (in German) (2 ed.). Georg Thieme Verlag.
ISBN978-3131179920.
OCLC237359985.
OL12671120M. (1st edition published in 1996)
Kuhl, H. (1999). "Hormonal Contraception". In Oettel, M.; Schillinger, E. (eds.). Estrogens and Antiestrogens II: Pharmacology and Clinical Application of Estrogens and Antiestrogens. Handbook of Experimental Pharmacology. Vol. 135 / 2. Berlin/Heidelberg: Springer. pp. 363–407.
doi:
10.1007/978-3-642-60107-1_18.
eISSN1865-0325.
ISBN978-3-642-64261-6.
ISSN0171-2004.
Kuhl H (December 1986). "Hormonsubstitution durch Injektionspräparate und Hautimplantate" [Hormone substitution by injectable preparations and skin implants]. Der Gynäkologe (in German). 19 (4): 241–247.
PMID3817596.
Kuhl, H. (December 1990). "Ovulationshemmer: Die Bedeutung der Östrogendosis" [Ovulation Preventives: The Significance of the Estrogen Dose]. Geburtshilfe und Frauenheilkunde (in German). 50 (12): 910–922.
doi:
10.1055/s-2008-1026392.
eISSN1438-8804.
ISSN0016-5751.
PMID2086334.
Kuhl, H. (18 April 1997). "Metabolische Effekte der Östrogene und Gestagene" [Metabolic effects of estrogens and progestogens]. Der Gynäkologe (in German). 30 (4): 357–369.
doi:
10.1007/PL00003042.
ISSN0017-5994.
S2CID43381309.
Kuhl, H.; Wiegratz, I. (1 February 2021). "Pharmakokinetik und Pharmakodynamik der in der assistierten Reproduktion verwendeten Gestagene" [Pharmacokinetics and pharmacodynamics of progestogens used in assisted reproduction]. Gynäkologische Endokrinologie (in German). 19 (2): 105–117.
doi:
10.1007/s10304-020-00372-5.
eISSN1610-2908.
ISSN1610-2894.
S2CID231744549.
Studies
Wiegratz, I.; Jung-Hoffmann, C.; Kuhl, H. (June 1995). "Effect of two oral contraceptives containing ethinylestradiol and gestodene or norgestimate upon androgen parameters and serum binding proteins". Contraception. 51 (6): 341–346.
doi:
10.1016/0010-7824(95)00098-U.
ISSN0010-7824.
PMID7554973.
^
abTaubert, H.-D.; Heil, H.; Kuhl, H. (1970). "Untersuchungen über die Wirkung von Äthynil-Oestradiol auf die L-Cystin-Aminopeptidosen-Aktivität im Hypothalamus der weiblichen Ratte" [Investigations on the Effect of Ethynil-Oestradiol on L-Cystine-amino-peptidase Activity in the Hypothalamus of Female Rats]. In Kracht, Joachim (ed.).
Endokrinologie der Entwicklung und Reifung: 16. Symposion, Ulm, 26.-28. Februar 1970. Symposion der Deutschen Gesellschaft für Endokrinologie. Vol. 16. Berlin/Heidelberg/New York: Springer-Verlag. pp. 288–289.
doi:
10.1007/978-3-642-80591-2.
ISBN978-3-642-80591-2.
OCLC863921711.
^Mueck, A. O.; Kuhl, H.; Braendle, W. (September 2004). "Ergebnisse und Kommentare zu der WHI-Studie mit Estrogen-Monotherapie" [Results of and Comments on the WHI Study with Estrogen Monotherapy]. Geburtshilfe und Frauenheilkunde (in German). 64 (9): 917–922.
doi:
10.1055/s-2004-821217.
eISSN1438-8804.
ISSN0016-5751.
S2CID71579060.
^Kuhl H (September 2004). "Is the elevated breast cancer risk observed in the WHI study an artifact?". Climacteric. 7 (3): 319–22.
doi:
10.1080/13697130400003337.
PMID15669557.
^Kuhl H, Stevenson J (June 2006). "The effect of medroxyprogesterone acetate on estrogen-dependent risks and benefits--an attempt to interpret the Women's Health Initiative results". Gynecol Endocrinol. 22 (6): 303–17.
doi:
10.1080/09513590600717368.
PMID16785155.
S2CID25260381.
^Kuhl, H.; Wiegratz, I. (1 February 2021). "Pharmakokinetik und Pharmakodynamik der in der assistierten Reproduktion verwendeten Gestagene" [Pharmacokinetics and pharmacodynamics of progestogens used in assisted reproduction]. Gynäkologische Endokrinologie (in German). 19 (2): 105–117.
doi:
10.1007/s10304-020-00372-5.
eISSN1610-2908.
ISSN1610-2894.
S2CID231744549.