Hegedus indole synthesis | |
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Named after | Louis S. Hegedus |
Reaction type | Ring forming reaction |
The Hegedus indole synthesis is a name reaction in organic chemistry that allows for the generation of indoles through palladium(II)-mediated oxidative cyclization of ortho-alkenyl anilines. [1] [2] [3] [4] [5] [6] The reaction can still take place for tosyl-protected amines. [4]
2-Allylaniline can be converted to 2-Methylindole using the Hegedus indole synthesis. [1]
Hegedus indole synthesis | |
---|---|
Named after | Louis S. Hegedus |
Reaction type | Ring forming reaction |
The Hegedus indole synthesis is a name reaction in organic chemistry that allows for the generation of indoles through palladium(II)-mediated oxidative cyclization of ortho-alkenyl anilines. [1] [2] [3] [4] [5] [6] The reaction can still take place for tosyl-protected amines. [4]
2-Allylaniline can be converted to 2-Methylindole using the Hegedus indole synthesis. [1]