Haplogroup JT | |
---|---|
Possible time of origin | 50,300 YBP |
Possible place of origin | Southwest Asia |
Ancestor | R2'JT |
Descendants | J, T |
Defining mutations | 11251, 15452A, 16126 [1] |
Haplogroup JT is a human mitochondrial DNA (mtDNA) haplogroup.
Haplogroup JT is descended from the macro-haplogroup R. It is the ancestral clade to the mitochondrial haplogroups J and T.
JT (predominantly J) was found among the ancient Etruscans. [2] The root level haplogroup JT* has been assigned to an ancient person found at the Colfiorito necropolis in Umbria in central Italy. [3]
The haplogroup has also been found among Iberomaurusian specimens dating from the Epipaleolithic at the Taforalt prehistoric site. [4] One ancient individual carried a haplotype, which correlates with either the JT clade or the haplogroup H subclade H14b1 (1/9; 11%). [5]
This phylogenetic tree of haplogroup JT subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation [1] and subsequent published research.
Maternally inherited ancient mtDNA variants have clear impact on the presentation of disease in a modern society. Superhaplogroup JT is an example of reduced risk of Parkinson's disease [6] And mitochondrial and mtDNa alterations continue to be promising disease biomarkers. [7] [8]
Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups | |||||||||||||||||||||||||||||||||||||||
Mitochondrial Eve ( L) | |||||||||||||||||||||||||||||||||||||||
L0 | L1–6 | ||||||||||||||||||||||||||||||||||||||
L1 | L2 | L3 | L4 | L5 | L6 | ||||||||||||||||||||||||||||||||||
M | N | ||||||||||||||||||||||||||||||||||||||
CZ | D | E | G | Q | O | A | S | R | I | W | X | Y | |||||||||||||||||||||||||||
C | Z | B | F | R0 | pre-JT | P | U | ||||||||||||||||||||||||||||||||
HV | JT | K | |||||||||||||||||||||||||||||||||||||
H | V | J | T |
Haplogroup JT | |
---|---|
Possible time of origin | 50,300 YBP |
Possible place of origin | Southwest Asia |
Ancestor | R2'JT |
Descendants | J, T |
Defining mutations | 11251, 15452A, 16126 [1] |
Haplogroup JT is a human mitochondrial DNA (mtDNA) haplogroup.
Haplogroup JT is descended from the macro-haplogroup R. It is the ancestral clade to the mitochondrial haplogroups J and T.
JT (predominantly J) was found among the ancient Etruscans. [2] The root level haplogroup JT* has been assigned to an ancient person found at the Colfiorito necropolis in Umbria in central Italy. [3]
The haplogroup has also been found among Iberomaurusian specimens dating from the Epipaleolithic at the Taforalt prehistoric site. [4] One ancient individual carried a haplotype, which correlates with either the JT clade or the haplogroup H subclade H14b1 (1/9; 11%). [5]
This phylogenetic tree of haplogroup JT subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation [1] and subsequent published research.
Maternally inherited ancient mtDNA variants have clear impact on the presentation of disease in a modern society. Superhaplogroup JT is an example of reduced risk of Parkinson's disease [6] And mitochondrial and mtDNa alterations continue to be promising disease biomarkers. [7] [8]
Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups | |||||||||||||||||||||||||||||||||||||||
Mitochondrial Eve ( L) | |||||||||||||||||||||||||||||||||||||||
L0 | L1–6 | ||||||||||||||||||||||||||||||||||||||
L1 | L2 | L3 | L4 | L5 | L6 | ||||||||||||||||||||||||||||||||||
M | N | ||||||||||||||||||||||||||||||||||||||
CZ | D | E | G | Q | O | A | S | R | I | W | X | Y | |||||||||||||||||||||||||||
C | Z | B | F | R0 | pre-JT | P | U | ||||||||||||||||||||||||||||||||
HV | JT | K | |||||||||||||||||||||||||||||||||||||
H | V | J | T |