From Wikipedia, the free encyclopedia
HP1BP3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases HP1BP3, HP1-BP74, HP1BP74, heterochromatin protein 1 binding protein 3
External IDs OMIM: 616072; MGI: 109369; HomoloGene: 7774; GeneCards: HP1BP3; OMA: HP1BP3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016287
NM_001372052

RefSeq (protein)
Location (UCSC) Chr 1: 20.74 – 20.79 Mb Chr 4: 137.94 – 137.97 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Heterochromatin protein 1, binding protein 3 is a protein that in humans is encoded by the HP1BP3 gene. [5] It has been identified as a novel subtype of the linker histone H1, involved in the structure of heterochromatin [6] [7] [8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000127483Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028759Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: heterochromatin protein 1, binding protein 3". Retrieved 2011-08-30.
  6. ^ Garfinkel BP, Melamed-Book N, Anuka E, Bustin M, Orly J (February 2015). "HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth". Nucleic Acids Research. 43 (4): 2074–90. doi: 10.1093/nar/gkv089. PMC  4344522. PMID  25662603.
  7. ^ Dutta B, Ren Y, Hao P, Sim KH, Cheow E, Adav S, Tam JP, Sze SK (September 2014). "Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression". Molecular & Cellular Proteomics. 13 (9): 2183–97. doi: 10.1074/mcp.M113.034975. PMC  4159643. PMID  24830416.
  8. ^ Hayashihara K, Uchiyama S, Shimamoto S, Kobayashi S, Tomschik M, Wakamatsu H, No D, Sugahara H, Hori N, Noda M, Ohkubo T, Zlatanova J, Matsunaga S, Fukui K (February 2010). "The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA". The Journal of Biological Chemistry. 285 (9): 6498–507. doi: 10.1074/jbc.M109.092833. PMC  2825445. PMID  20042602.

Further reading

From Wikipedia, the free encyclopedia
HP1BP3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases HP1BP3, HP1-BP74, HP1BP74, heterochromatin protein 1 binding protein 3
External IDs OMIM: 616072; MGI: 109369; HomoloGene: 7774; GeneCards: HP1BP3; OMA: HP1BP3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016287
NM_001372052

RefSeq (protein)
Location (UCSC) Chr 1: 20.74 – 20.79 Mb Chr 4: 137.94 – 137.97 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Heterochromatin protein 1, binding protein 3 is a protein that in humans is encoded by the HP1BP3 gene. [5] It has been identified as a novel subtype of the linker histone H1, involved in the structure of heterochromatin [6] [7] [8]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000127483Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028759Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: heterochromatin protein 1, binding protein 3". Retrieved 2011-08-30.
  6. ^ Garfinkel BP, Melamed-Book N, Anuka E, Bustin M, Orly J (February 2015). "HP1BP3 is a novel histone H1 related protein with essential roles in viability and growth". Nucleic Acids Research. 43 (4): 2074–90. doi: 10.1093/nar/gkv089. PMC  4344522. PMID  25662603.
  7. ^ Dutta B, Ren Y, Hao P, Sim KH, Cheow E, Adav S, Tam JP, Sze SK (September 2014). "Profiling of the Chromatin-associated Proteome Identifies HP1BP3 as a Novel Regulator of Cell Cycle Progression". Molecular & Cellular Proteomics. 13 (9): 2183–97. doi: 10.1074/mcp.M113.034975. PMC  4159643. PMID  24830416.
  8. ^ Hayashihara K, Uchiyama S, Shimamoto S, Kobayashi S, Tomschik M, Wakamatsu H, No D, Sugahara H, Hori N, Noda M, Ohkubo T, Zlatanova J, Matsunaga S, Fukui K (February 2010). "The middle region of an HP1-binding protein, HP1-BP74, associates with linker DNA at the entry/exit site of nucleosomal DNA". The Journal of Biological Chemistry. 285 (9): 6498–507. doi: 10.1074/jbc.M109.092833. PMC  2825445. PMID  20042602.

Further reading


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