Histone H1oo is a
protein that in humans is encoded by the H1FOOgene.[5][6]
Function
Histones are basic nuclear proteins that are responsible for the
nucleosome structure of the chromosomal fiber in
eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.[6]
Tanaka Y, Kato S, Tanaka M, et al. (2003). "Structure and expression of the human oocyte-specific histone H1 gene elucidated by direct RT-nested PCR of a single oocyte". Biochem. Biophys. Res. Commun. 304 (2): 351–7.
doi:
10.1016/S0006-291X(03)00610-7.
PMID12711322.
Histone H1oo is a
protein that in humans is encoded by the H1FOOgene.[5][6]
Function
Histones are basic nuclear proteins that are responsible for the
nucleosome structure of the chromosomal fiber in
eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.[6]
Tanaka Y, Kato S, Tanaka M, et al. (2003). "Structure and expression of the human oocyte-specific histone H1 gene elucidated by direct RT-nested PCR of a single oocyte". Biochem. Biophys. Res. Commun. 304 (2): 351–7.
doi:
10.1016/S0006-291X(03)00610-7.
PMID12711322.