GTP BINDING PROTEIN 2

GTPBP2
Identifiers
Aliases	GTPBP2, GTP binding protein 2
External IDs	OMIM: 607434; MGI: 1860138; HomoloGene: 10420; GeneCards: GTPBP2; OMA: GTPBP2 - orthologs
Gene location ( Human)
Chr.	Chromosome 6 (human)
End	43,629,162 bp
Gene location ( Mouse)
Chr.	Chromosome 17 (mouse)
End	46,480,296 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; mucosa of transverse colon; ; minor salivary glands; ; anterior pituitary; ; upper lobe of left lung; ; granulocyte; ; right lung; ; gastric mucosa; ; monocyte;
	Top expressed in
	neural layer of retina; ; granulocyte; ; motor neuron; ; lip; ; Rostral migratory stream; ; Paneth cell; ; pyloric antrum; ; ciliary body; ; fossa; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity; translation elongation factor activity;
Cellular component	intracellular membrane-bounded organelle; extracellular region; platelet alpha granule lumen;
Biological process	platelet degranulation; biological process; translational elongation;
	Sources: Amigo / QuickGO
Orthologs
	54676
	56055
	ENSG00000172432
	ENSMUSG00000023952
	Q9BX10
	Q3UJK4
	NM_019096; NM_001286216
	NM_001145979; NM_019581; NM_001357745
	NP_001273145; NP_061969; NP_061969.3
	NP_001139451; NP_062527; NP_001344674
	Wikidata
View/Edit Human	View/Edit Mouse

GTP binding protein 2 is a protein that in humans is encoded by the GTPBP2 gene. ^[5]

Function

GTP-binding proteins, or G proteins, constitute a superfamily capable of binding GTP or GDP. G proteins are activated by binding GTP and are inactivated by hydrolyzing GTP to GDP. This general mechanism enables G proteins to perform a wide range of biologic activities.

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000172432 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000023952 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GTP binding protein 2". Retrieved 2017-01-18.

Function

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Further reading

Function

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