Gran Sasso (Italian for "Large Stone") may refer to any of several nearby locations among Gran Sasso d'Italia, the highest mountain in central Italy:

• Isola del Gran Sasso d'Italia, a town in Italy near the mountain;
• Gran Sasso e Monti della Laga National Park, which surrounds the town and mountain;
• Gran Sasso pass a highway tunnel under the mountain; or
• Laboratori Nazionali del Gran Sasso, the largest underground laboratory in the world, under the midpoint of the tunnel.

This disambiguation page lists articles associated with the title Gran Sasso.
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