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Names | |
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Preferred IUPAC name
(2R)-3-(3,4-Dihydroxyphenyl)-2-{[4-(3,4-dihydroxyphenyl)-6,7-dihydroxynaphthalene-2-carbonyl]oxy}propanoic acid | |
Identifiers | |
3D model (
JSmol)
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ChemSpider | |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C26H20O10 | |
Molar mass | 492.436 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Globoidnan A is a lignan found in Eucalyptus globoidea, a tree native to Australia.
The molecule has been found to weakly inhibit the action of HIV integrase ( IC50 = 0.64 μM) in vitro. [1] HIV integrase is an enzyme which is responsible for the introduction of HIV viral DNA into a host's cellular DNA. It is not known that globoidnan A inhibits the action of other retroviral integrases.
![]() | |
Names | |
---|---|
Preferred IUPAC name
(2R)-3-(3,4-Dihydroxyphenyl)-2-{[4-(3,4-dihydroxyphenyl)-6,7-dihydroxynaphthalene-2-carbonyl]oxy}propanoic acid | |
Identifiers | |
3D model (
JSmol)
|
|
ChemSpider | |
PubChem
CID
|
|
UNII | |
CompTox Dashboard (
EPA)
|
|
| |
| |
Properties | |
C26H20O10 | |
Molar mass | 492.436 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Globoidnan A is a lignan found in Eucalyptus globoidea, a tree native to Australia.
The molecule has been found to weakly inhibit the action of HIV integrase ( IC50 = 0.64 μM) in vitro. [1] HIV integrase is an enzyme which is responsible for the introduction of HIV viral DNA into a host's cellular DNA. It is not known that globoidnan A inhibits the action of other retroviral integrases.