Company type | Public |
---|---|
Nasdaq: GBIM | |
Industry | Biotechnology |
Founded | 1 January 1995 |
Headquarters | , |
Number of employees | 22 (Dec 2014) [1] |
Website | GlobeImmune.com |
GlobeImmune, Inc. is a clinical-stage public biopharmaceutical company headquartered in Louisville, Colorado, that develops therapeutic vaccines to treat cancer and infectious diseases. [2] As of August 2014 [update], the company had no marketed products. [3][ self-published source] GlobeImmune’s therapeutic vaccines are developed on the company’s Tarmogen immunotherapy platform. Tarmogens are made from genetically modified yeast that express one or more disease-associated antigens. Tarmogens activate T cells to specifically target and eliminate diseased cells with the same target antigen.
The company has partnerships with Celgene (established in 2009) [2] and the National Cancer Institute for the development of cancer vaccines. [4] [5] Their collaboration with Gilead for the development of therapeutic vaccines for the treatment of hepatitis B was terminated in November 2016 after the product they were developing failed a clinical trial the year before. [6]
With respect to financing in the absence of revenue, the company raised US$17,500,000 through a Series E Preferred Stock offering in January 2010. [2]
As of August 2015 [update], GlobeImmune had two therapeutic vaccines in clinical trials, GI-6207 and GI-6301, for the treatment of various cancers. [7] Completed trials have addressed two other candidates, GI-4000 (the company's lead oncology candidate as of 2010) [2] and GI-5005. [7] Despite there being three ongoing trials, in July 2015 the company announced it would eliminate "most of its workforce positions" shortly following the failure of a trial examining GI-4774. [1]
In March 2017, GlobeImmune announced that it has entered into a definitive purchase agreement for the sale of shares of its common stock to NantCell, Inc. [8]
Company type | Public |
---|---|
Nasdaq: GBIM | |
Industry | Biotechnology |
Founded | 1 January 1995 |
Headquarters | , |
Number of employees | 22 (Dec 2014) [1] |
Website | GlobeImmune.com |
GlobeImmune, Inc. is a clinical-stage public biopharmaceutical company headquartered in Louisville, Colorado, that develops therapeutic vaccines to treat cancer and infectious diseases. [2] As of August 2014 [update], the company had no marketed products. [3][ self-published source] GlobeImmune’s therapeutic vaccines are developed on the company’s Tarmogen immunotherapy platform. Tarmogens are made from genetically modified yeast that express one or more disease-associated antigens. Tarmogens activate T cells to specifically target and eliminate diseased cells with the same target antigen.
The company has partnerships with Celgene (established in 2009) [2] and the National Cancer Institute for the development of cancer vaccines. [4] [5] Their collaboration with Gilead for the development of therapeutic vaccines for the treatment of hepatitis B was terminated in November 2016 after the product they were developing failed a clinical trial the year before. [6]
With respect to financing in the absence of revenue, the company raised US$17,500,000 through a Series E Preferred Stock offering in January 2010. [2]
As of August 2015 [update], GlobeImmune had two therapeutic vaccines in clinical trials, GI-6207 and GI-6301, for the treatment of various cancers. [7] Completed trials have addressed two other candidates, GI-4000 (the company's lead oncology candidate as of 2010) [2] and GI-5005. [7] Despite there being three ongoing trials, in July 2015 the company announced it would eliminate "most of its workforce positions" shortly following the failure of a trial examining GI-4774. [1]
In March 2017, GlobeImmune announced that it has entered into a definitive purchase agreement for the sale of shares of its common stock to NantCell, Inc. [8]