PhotosBiographyFacebookTwitter

From Wikipedia, the free encyclopedia
Gerard Kleywegt
Born
Gerrit Jacob Kleijwegt

1962 (age 61–62)
Rozenburg, Nederland
NationalityDutch
Alma mater University of Utrecht
Scientific career
Fields
Institutions European Bioinformatics Institute
University of Upsala
Thesis Computer-assisted assignment of 2D and 3D NMR spectra of proteins (Computer-ondersteunde toekenning van 2D en 3D NMR spectra van eiwitten)  (1991)
Website http://www.ebi.ac.uk/about/people/gerard-kleywegt

Gerard Jacob Kleywegt (born 5 June 1962, in Rozenburg) is a Dutch X-ray crystallographer and the former team leader of the Protein Data Bank in Europe at the EBI; [1] [2] [3] [4] a member of the Worldwide Protein Data Bank. [5] [6]

Education

Kleywegt obtained his PhD from the University of Utrecht in 1991.

Career

After his PhD, Kleywegt did postdoctoral research with Alwyn Jones at Uppsala University. [7] [8] before moving to the EBI.

Research

Kleywegt's research focuses on protein crystallography [9] [10] [11] and the Protein Data Bank. [12] [13] [14] [15] [16] [17] [18]

References

  1. ^ "Looking back on 2016".
  2. ^ "Gerard Kleywegt research group page at the EBI". Archived from the original on 2014-10-20.
  3. ^ Garwoord, Jeremy (May 2009) "A Guardian of Structural Integrity". Lab Times. pp. 19-23
  4. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H.; Markley, J. L.; Burley, S. K. (2010). "Safeguarding the integrity of protein archive". Nature. 463 (7280): 425. doi: 10.1038/463425c. PMC  4456675. PMID  20110969.
  5. ^ Lewis, T. E.; Sillitoe, I; Andreeva, A; Blundell, T. L.; Buchan, D. W.; Chothia, C; Cozzetto, D; Dana, J. M.; Filippis, I; Gough, J; Jones, D. T.; Kelley, L. A.; Kleywegt, G. J.; Minneci, F; Mistry, J; Murzin, A. G.; Ochoa-Montaño, B; Oates, M. E.; Punta, M; Rackham, O. J.; Stahlhacke, J; Sternberg, M. J.; Velankar, S; Orengo, C (2015). "Genome3D: Exploiting structure to help users understand their sequences". Nucleic Acids Research. 43 (Database issue): D382-6. doi: 10.1093/nar/gku973. PMC  4384030. PMID  25348407.
  6. ^ Lewis, T. E.; Sillitoe, I; Andreeva, A; Blundell, T. L.; Buchan, D. W.; Chothia, C; Cuff, A; Dana, J. M.; Filippis, I; Gough, J; Hunter, S; Jones, D. T.; Kelley, L. A.; Kleywegt, G. J.; Minneci, F; Mitchell, A; Murzin, A. G.; Ochoa-Montaño, B; Rackham, O. J.; Smith, J; Sternberg, M. J.; Velankar, S; Yeats, C; Orengo, C (2013). "Genome3D: A UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains". Nucleic Acids Research. 41 (Database issue): D499-507. doi: 10.1093/nar/gks1266. PMC  3531217. PMID  23203986.
  7. ^ Jones, T. A.; Kleywegt, G. J. (2007). "Experimental Data for Structure Papers". Science. 317 (5835): 194c. doi: 10.1126/science.317.5835.194c.
  8. ^ Kleywegt, G. J.; Jones, T. A. (1996). "Phi/psi-chology: Ramachandran revisited". Structure. 4 (12): 1395–400. doi: 10.1016/s0969-2126(96)00147-5. PMID  8994966.
  9. ^ Read, R. J.; Adams, P. D.; Arendall Wb, 3rd; Brunger, A. T.; Emsley, P; Joosten, R. P.; Kleywegt, G. J.; Krissinel, E. B.; Lütteke, T; Otwinowski, Z; Perrakis, A; Richardson, J. S.; Sheffler, W. H.; Smith, J. L.; Tickle, I. J.; Vriend, G; Zwart, P. H. (2011). "A new generation of crystallographic validation tools for the protein data bank". Structure. 19 (10): 1395–412. doi: 10.1016/j.str.2011.08.006. PMC  3195755. PMID  22000512.{{ cite journal}}: CS1 maint: numeric names: authors list ( link)
  10. ^ Read, R. J.; Kleywegt, G. J. (2009). "Case-controlled structure validation". Acta Crystallographica Section D. 65 (Pt 2): 140–7. doi: 10.1107/S0907444908041085. PMC  2631636. PMID  19171969.
  11. ^ Kleywegt, G. J.; Read, R. J. (1997). "Not your average density". Structure. 5 (12): 1557–69. doi: 10.1016/s0969-2126(97)00305-5. PMID  9438862.
  12. ^ Montelione, G. T.; Nilges, M; Bax, A; Güntert, P; Herrmann, T; Richardson, J. S.; Schwieters, C. D.; Vranken, W. F.; Vuister, G. W.; Wishart, D. S.; Berman, H. M.; Kleywegt, G. J.; Markley, J. L. (2013). "Recommendations of the wwPDB NMR Validation Task Force". Structure. 21 (9): 1563–70. doi: 10.1016/j.str.2013.07.021. PMC  3884077. PMID  24010715.
  13. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2013). "How community has shaped the Protein Data Bank". Structure. 21 (9): 1485–91. doi: 10.1016/j.str.2013.07.010. PMC  4435976. PMID  24010707.
  14. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2013). "The future of the protein data bank". Biopolymers. 99 (3): 218–22. doi: 10.1002/bip.22132. PMC  3684242. PMID  23023942.
  15. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2012). "The Protein Data Bank at 40: Reflecting on the past to prepare for the future". Structure. 20 (3): 391–6. doi: 10.1016/j.str.2012.01.010. PMC  3501388. PMID  22404998.
  16. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H.; Markley, J. L.; Burley, S. K. (2010). "Safeguarding the integrity of protein archive". Nature. 463 (7280): 425. doi: 10.1038/463425c. PMC  4456675. PMID  20110969.
  17. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2014). "The Protein Data Bank archive as an open data resource". Journal of Computer-Aided Molecular Design. 28 (10): 1009–14. doi: 10.1007/s10822-014-9770-y. PMC  4196035. PMID  25062767.
  18. ^ Berman, H. M.; Burley, S. K.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2014). "Response to on prompt update of literature references in the Protein Data Bank". Acta Crystallographica Section D. 70 (Pt 10): 2780. doi: 10.1107/S1399004714020513. PMC  4984264. PMID  25286863.
From Wikipedia, the free encyclopedia
Gerard Kleywegt
Born
Gerrit Jacob Kleijwegt

1962 (age 61–62)
Rozenburg, Nederland
NationalityDutch
Alma mater University of Utrecht
Scientific career
Fields
Institutions European Bioinformatics Institute
University of Upsala
Thesis Computer-assisted assignment of 2D and 3D NMR spectra of proteins (Computer-ondersteunde toekenning van 2D en 3D NMR spectra van eiwitten)  (1991)
Website http://www.ebi.ac.uk/about/people/gerard-kleywegt

Gerard Jacob Kleywegt (born 5 June 1962, in Rozenburg) is a Dutch X-ray crystallographer and the former team leader of the Protein Data Bank in Europe at the EBI; [1] [2] [3] [4] a member of the Worldwide Protein Data Bank. [5] [6]

Education

Kleywegt obtained his PhD from the University of Utrecht in 1991.

Career

After his PhD, Kleywegt did postdoctoral research with Alwyn Jones at Uppsala University. [7] [8] before moving to the EBI.

Research

Kleywegt's research focuses on protein crystallography [9] [10] [11] and the Protein Data Bank. [12] [13] [14] [15] [16] [17] [18]

References

  1. ^ "Looking back on 2016".
  2. ^ "Gerard Kleywegt research group page at the EBI". Archived from the original on 2014-10-20.
  3. ^ Garwoord, Jeremy (May 2009) "A Guardian of Structural Integrity". Lab Times. pp. 19-23
  4. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H.; Markley, J. L.; Burley, S. K. (2010). "Safeguarding the integrity of protein archive". Nature. 463 (7280): 425. doi: 10.1038/463425c. PMC  4456675. PMID  20110969.
  5. ^ Lewis, T. E.; Sillitoe, I; Andreeva, A; Blundell, T. L.; Buchan, D. W.; Chothia, C; Cozzetto, D; Dana, J. M.; Filippis, I; Gough, J; Jones, D. T.; Kelley, L. A.; Kleywegt, G. J.; Minneci, F; Mistry, J; Murzin, A. G.; Ochoa-Montaño, B; Oates, M. E.; Punta, M; Rackham, O. J.; Stahlhacke, J; Sternberg, M. J.; Velankar, S; Orengo, C (2015). "Genome3D: Exploiting structure to help users understand their sequences". Nucleic Acids Research. 43 (Database issue): D382-6. doi: 10.1093/nar/gku973. PMC  4384030. PMID  25348407.
  6. ^ Lewis, T. E.; Sillitoe, I; Andreeva, A; Blundell, T. L.; Buchan, D. W.; Chothia, C; Cuff, A; Dana, J. M.; Filippis, I; Gough, J; Hunter, S; Jones, D. T.; Kelley, L. A.; Kleywegt, G. J.; Minneci, F; Mitchell, A; Murzin, A. G.; Ochoa-Montaño, B; Rackham, O. J.; Smith, J; Sternberg, M. J.; Velankar, S; Yeats, C; Orengo, C (2013). "Genome3D: A UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains". Nucleic Acids Research. 41 (Database issue): D499-507. doi: 10.1093/nar/gks1266. PMC  3531217. PMID  23203986.
  7. ^ Jones, T. A.; Kleywegt, G. J. (2007). "Experimental Data for Structure Papers". Science. 317 (5835): 194c. doi: 10.1126/science.317.5835.194c.
  8. ^ Kleywegt, G. J.; Jones, T. A. (1996). "Phi/psi-chology: Ramachandran revisited". Structure. 4 (12): 1395–400. doi: 10.1016/s0969-2126(96)00147-5. PMID  8994966.
  9. ^ Read, R. J.; Adams, P. D.; Arendall Wb, 3rd; Brunger, A. T.; Emsley, P; Joosten, R. P.; Kleywegt, G. J.; Krissinel, E. B.; Lütteke, T; Otwinowski, Z; Perrakis, A; Richardson, J. S.; Sheffler, W. H.; Smith, J. L.; Tickle, I. J.; Vriend, G; Zwart, P. H. (2011). "A new generation of crystallographic validation tools for the protein data bank". Structure. 19 (10): 1395–412. doi: 10.1016/j.str.2011.08.006. PMC  3195755. PMID  22000512.{{ cite journal}}: CS1 maint: numeric names: authors list ( link)
  10. ^ Read, R. J.; Kleywegt, G. J. (2009). "Case-controlled structure validation". Acta Crystallographica Section D. 65 (Pt 2): 140–7. doi: 10.1107/S0907444908041085. PMC  2631636. PMID  19171969.
  11. ^ Kleywegt, G. J.; Read, R. J. (1997). "Not your average density". Structure. 5 (12): 1557–69. doi: 10.1016/s0969-2126(97)00305-5. PMID  9438862.
  12. ^ Montelione, G. T.; Nilges, M; Bax, A; Güntert, P; Herrmann, T; Richardson, J. S.; Schwieters, C. D.; Vranken, W. F.; Vuister, G. W.; Wishart, D. S.; Berman, H. M.; Kleywegt, G. J.; Markley, J. L. (2013). "Recommendations of the wwPDB NMR Validation Task Force". Structure. 21 (9): 1563–70. doi: 10.1016/j.str.2013.07.021. PMC  3884077. PMID  24010715.
  13. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2013). "How community has shaped the Protein Data Bank". Structure. 21 (9): 1485–91. doi: 10.1016/j.str.2013.07.010. PMC  4435976. PMID  24010707.
  14. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2013). "The future of the protein data bank". Biopolymers. 99 (3): 218–22. doi: 10.1002/bip.22132. PMC  3684242. PMID  23023942.
  15. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2012). "The Protein Data Bank at 40: Reflecting on the past to prepare for the future". Structure. 20 (3): 391–6. doi: 10.1016/j.str.2012.01.010. PMC  3501388. PMID  22404998.
  16. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H.; Markley, J. L.; Burley, S. K. (2010). "Safeguarding the integrity of protein archive". Nature. 463 (7280): 425. doi: 10.1038/463425c. PMC  4456675. PMID  20110969.
  17. ^ Berman, H. M.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2014). "The Protein Data Bank archive as an open data resource". Journal of Computer-Aided Molecular Design. 28 (10): 1009–14. doi: 10.1007/s10822-014-9770-y. PMC  4196035. PMID  25062767.
  18. ^ Berman, H. M.; Burley, S. K.; Kleywegt, G. J.; Nakamura, H; Markley, J. L. (2014). "Response to on prompt update of literature references in the Protein Data Bank". Acta Crystallographica Section D. 70 (Pt 10): 2780. doi: 10.1107/S1399004714020513. PMC  4984264. PMID  25286863.

Videos

Youtube | Vimeo | Bing

Websites

Google | Yahoo | Bing

Encyclopedia

Google | Yahoo | Bing

Facebook