American plant biologist
Georg Jander is an American
plant biologist at the
Boyce Thompson Institute in
Ithaca, New York .
[1] He has an adjunct appointment in the Plant Biology Section of the School of Integrative Plant Sciences at
Cornell University .
[2] Jander is known for his molecular research identifying genes for biochemical compounds of ecological and agricultural importance, particularly those plant traits involved in resistance to insect pests.
[3]
[4]
[5]
Jander earned his undergraduate degree in computer science from the
McKelvey School of Engineering at
Washington University in St. Louis in 1983.
[6] As a Ph.D. student in Microbiology and Molecular Genetics, working under the supervision of
Jon Beckwith at
Harvard Medical School , he wrote a thesis titled Genetic studies on protein folding and protein secretion in Escherichia coli , and is an author of journal publications in this research area.
[3]
[7]
[8]
[9]
[10]
[11] While working as a postdoctoral fellow in the lab of
Fred Ausubel at
Massachusetts General Hospital , Jander initiated research on the molecular biology and genetics of
Arabidopsis thaliana defense against insect herbivores.
[12]
[13]
[14]
[15] He continued his research training in plant genetics and molecular biology as a scientist at the
Monsanto Company from 1998 to 2002.
[16]
[17]
[18]
[19]
[20]
[21]
Since joining the
Boyce Thompson Institute as a faculty member in 2002, Jander has studied several plant species, including maize (
Zea mays ),
[22]
[23]
[24]
[25] mouse-ear cress (
Arabidopsis ),
[26]
[27]
[28] wallflowers in the genus
Erysimum .
[29]
[30]
[31]
[32] In each plant species, Jander's laboratory uses techniques in biochemical genetics to identify the genetic causes of plant secondary metabolism involved in plant defenses against insects. A particular focus of the Jander lab has been research involving plant interactions with aphids.
[33]
[34]
[35]
[36]
[37]
[38]
[39]
[40]
[41]
[42] Jander's research publications have been cited more than 17,000 times by other scientists.
[3]
Jander's research collaborators and co-authors in the field of chemical ecology include:
Anurag Agrawal , Clare Casteel, Andre Kessler, Gaurav Moghe, Katja Poveda,
Rob Raguso , and
Jennifer Thaler at
Cornell University , Eric Schmelz at
UC San Diego , Melkamu Woldemariam at
The College of New Jersey , Cynthia Holland at
Williams College , Asaph Aharoni at the
Weizmann Institute , and Tobias Züst at the
University of Zurich .
[3]
Graduate student alumni of the Jander lab are: Tengfang Huang, VP for Research at Elo Life Systems,
[43] Dezi Elzinga, research scientist at Zymtronix,
[44]
[45] John Ramsey, research molecular biologist at the
USDA ,
[46] Yann-Ru Lou, assistant professor in Plant Biology at
UC Davis ,
[47] and Shaoqun (Simon) Zhou, principal investigator at the Agricultural Genomics Institute of
Shenzhen .
[48]
Since 2005, Jander has been the principal investigator for a plant-focused undergraduate summer internship program at the Boyce Thompson Institute.
[49] Undergraduate research internships are currently funded by
US National Science Foundation award #1850796 and
United States Department of Agriculture award #2022-67037-3622.
[50]
[51] Notable alumni of the summer research program include Adam Steinbrenner, assistant professor at the
University of Washington ,
[52] Kaitlin Gold, assistant professor at
Cornell University ,
[53] and Karl Kremling, senior scientist at Inari Agriculture.
[54]
[55]
^
"Welcome to Boyce Thompson Institute - Inspired by how plants work for humanity" . Boyce Thompson Institute . Retrieved 2022-12-24 .
^
"Georg Jander" . CALS . 20 April 2020. Retrieved 2022-12-24 .
^
a
b
c
d
"Georg Jander" . scholar.google.com . Retrieved 2022-12-24 .
^
"Georg Jander" . Boyce Thompson Institute . Retrieved 2022-12-24 .
^ Waldron, Patricia.
"Jander Unlocks Molecular Pathways of Plants and Empowers People" . Boyce Thompson Institute . Retrieved 2022-12-24 .
^
"Alumni and Friends - Washington University in St. Louis" . Alumni and Friends . Retrieved 2022-12-24 .
^ Jander, G; Cronan, J E; Beckwith, J (1996).
"Biotinylation in vivo as a sensitive indicator of protein secretion and membrane protein insertion" . Journal of Bacteriology . 178 (11): 3049–3058.
doi :
10.1128/jb.178.11.3049-3058.1996 .
ISSN
0021-9193 .
PMC
178051 .
PMID
8655479 .
^ Guilhot, C; Jander, G; Martin, N L; Beckwith, J (1995-10-10).
"Evidence that the pathway of disulfide bond formation in Escherichia coli involves interactions between the cysteines of DsbB and DsbA" . Proceedings of the National Academy of Sciences . 92 (21): 9895–9899.
Bibcode :
1995PNAS...92.9895G .
doi :
10.1073/pnas.92.21.9895 .
ISSN
0027-8424 .
PMC
40909 .
PMID
7568240 .
^ Jander, G.; Martin, N.L.; Beckwith, J. (1994).
"Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation" . The EMBO Journal . 13 (21): 5121–5127.
doi :
10.1002/j.1460-2075.1994.tb06841.x .
PMC
395459 .
PMID
7957076 .
^ Jander, G.; Martin, N.L.; Beckwith, J. (1994).
"Two cysteines in each periplasmic domain of the membrane protein DsbB are required for its function in protein disulfide bond formation" . The EMBO Journal . 13 (21): 5121–5127.
doi :
10.1002/j.1460-2075.1994.tb06841.x .
ISSN
0261-4189 .
PMC
395459 .
PMID
7957076 .
^ Braun, V; Neuss, B; Ruan, Y; Schiebel, E; Schöffler, H; Jander, G (1987).
"Identification of the Serratia marcescens hemolysin determinant by cloning into Escherichia coli" . Journal of Bacteriology . 169 (5): 2113–2120.
doi :
10.1128/jb.169.5.2113-2120.1987 .
ISSN
0021-9193 .
PMC
212107 .
PMID
2437098 .
^ Jander, Georg; Cui, Jianping; Nhan, Betty; Pierce, Naomi E.; Ausubel, Frederick M. (2001-06-01).
"The TASTY Locus on Chromosome 1 of Arabidopsis Affects Feeding of the Insect Herbivore Trichoplusia ni" . Plant Physiology . 126 (2): 890–898.
doi :
10.1104/pp.126.2.890 .
ISSN
1532-2548 .
PMC
111178 .
PMID
11402216 .
^ Cui, Jianping; Jander, Georg; Racki, Lisa R.; Kim, Paul D.; Pierce, Naomi E.; Ausubel, Frederick M. (2002-06-01).
"Signals Involved in Arabidopsis Resistance to Trichoplusia ni Caterpillars Induced by Virulent and Avirulent Strains of the Phytopathogen Pseudomonas syringae" . Plant Physiology . 129 (2): 551–564.
doi :
10.1104/pp.010815 .
ISSN
1532-2548 .
PMC
161673 .
PMID
12068100 .
^ Bush, Jenifer; Jander, Georg; Ausubel, Frederick M. (2006-03-15),
"Prevention and Control of Pests and Diseases" , Arabidopsis Protocols , vol. 323, New Jersey: Humana Press, pp. 13–26,
doi :
10.1385/1-59745-003-0:13 ,
ISBN
978-1-59745-003-4 ,
PMID
16739564 ,
S2CID
25762547 , retrieved 2022-12-24
^ Clay, Nicole K.; Adio, Adewale M.; Denoux, Carine; Jander, Georg; Ausubel, Frederick M. (2009-01-02).
"Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response" . Science . 323 (5910): 95–101.
Bibcode :
2009Sci...323...95C .
doi :
10.1126/science.1164627 .
ISSN
0036-8075 .
PMC
2630859 .
PMID
19095898 .
^ Jander, Georg; Baerson, Scott R.; Hudak, Jebecka A.; Gonzalez, Kathleen A.; Gruys, Kenneth J.; Last, Robert L. (2003-01-01).
"Ethylmethanesulfonate Saturation Mutagenesis in Arabidopsis to Determine Frequency of Herbicide Resistance" . Plant Physiology . 131 (1): 139–146.
doi :
10.1104/pp.102.010397 .
ISSN
0032-0889 .
PMC
166794 .
PMID
12529522 .
^ Jander, Georg; Norris, Susan R.; Rounsley, Steven D.; Bush, David F.; Levin, Irena M.; Last, Robert L. (2002-06-01).
"Arabidopsis Map-Based Cloning in the Post-Genome Era" . Plant Physiology . 129 (2): 440–450.
doi :
10.1104/pp.003533 .
ISSN
1532-2548 .
PMC
1540230 .
PMID
12068090 .
^ Jander, Georg; Norris, Susan R.; Joshi, Vijay; Fraga, Michele; Rugg, Arthur; Yu, Shaoxia; Li, Lily; Last, Robert L. (2004).
"Application of a high-throughput HPLC-MS/MS assay to Arabidopsis mutant screening; evidence that threonine aldolase plays a role in seed nutritional quality" . The Plant Journal . 39 (3): 465–475.
doi :
10.1111/j.1365-313X.2004.02140.x .
PMID
15255874 .
^ Kim, Jae Hak; Durrett, Timothy P.; Last, Robert L.; Jander, Georg (2004).
"Characterization of the Arabidopsis TU8 Glucosinolate Mutation,an Allele of TERMINAL FLOWER2" . Plant Molecular Biology . 54 (5): 671–682.
doi :
10.1023/B:PLAN.0000040897.49151.98 .
ISSN
0167-4412 .
PMID
15356387 .
S2CID
14836925 .
^ Kliebenstein, Daniel J.; D’Auria, John C.; Behere, Aditi S.; Kim, Jae Hak; Gunderson, Kevin L.; Breen, John N.; Lee, Grace; Gershenzon, Jonathan; Last, Robert L.; Jander, Georg (2007-08-07).
"Characterization of seed-specific benzoyloxyglucosinolate mutations in Arabidopsis thaliana: Benzoyloxyglucosinolates in Arabidopsis" . The Plant Journal . 51 (6): 1062–1076.
doi :
10.1111/j.1365-313X.2007.03205.x .
PMID
17651367 .
^ Lee, Minsang; Huang, Tengfang; Toro-Ramos, Tatiana; Fraga, Michele; Last, Robert L.; Jander, Georg (2008).
"Reduced activity of Arabidopsis thaliana HMT2, a methionine biosynthetic enzyme, increases seed methionine content" . The Plant Journal . 54 (2): 310–320.
doi :
10.1111/j.1365-313X.2008.03419.x .
ISSN
0960-7412 .
PMID
18208517 .
^ Richter, Annett; Powell, Adrian F.; Mirzaei, Mahdieh; Wang, Lucy J.; Movahed, Navid; Miller, Julia K.; Piñeros, Miguel A.; Jander, Georg (2021).
"Indole‐3‐glycerolphosphate synthase, a branchpoint for the biosynthesis of tryptophan, indole, and benzoxazinoids in maize" . The Plant Journal . 106 (1): 245–257.
doi :
10.1111/tpj.15163 .
ISSN
0960-7412 .
PMID
33458870 .
S2CID
231635326 .
^ Zhou, Shaoqun; Bae, Justin S.; Bergstrom, Gary C.; Jander, Georg (2018).
"Fusarium graminearum‐ induced shoot elongation and root reduction in maize seedlings correlate with later seedling blight severity" . Plant Direct . 2 (7): e00075.
doi :
10.1002/pld3.75 .
ISSN
2475-4455 .
PMC
6508817 .
PMID
31245738 .
^ Zhou, Shaoqun; Kremling, Karl A.; Bandillo, Nonoy; Richter, Annett; Zhang, Ying K.; Ahern, Kevin R.; Artyukhin, Alexander B.; Hui, Joshua X.; Younkin, Gordon C.; Schroeder, Frank C.; Buckler, Edward S.; Jander, Georg (2019).
"Metabolome-Scale Genome-Wide Association Studies Reveal Chemical Diversity and Genetic Control of Maize Specialized Metabolites" . The Plant Cell . 31 (5): 937–955.
doi :
10.1105/tpc.18.00772 .
ISSN
1040-4651 .
PMC
6533025 .
PMID
30923231 .
^ Zhou, Shaoqun; Zhang, Ying K.; Kremling, Karl A.; Ding, Yezhang; Bennett, John S.; Bae, Justin S.; Kim, Dean K.; Ackerman, Hayley H.; Kolomiets, Michael V.; Schmelz, Eric A.; Schroeder, Frank C.; Buckler, Edward S.; Jander, Georg (2019).
"Ethylene signaling regulates natural variation in the abundance of antifungal acetylated diferuloylsucroses and Fusarium graminearum resistance in maize seedling roots" . New Phytologist . 221 (4): 2096–2111.
doi :
10.1111/nph.15520 .
ISSN
0028-646X .
PMID
30289553 .
^ Lou, Yann‐Ru; Ahmed, Sheaza; Yan, Jian; Adio, Adewale M.; Powell, Hannah M.; Morris, Paul F.; Jander, Georg (2020).
"Arabidopsis ADC1 functions as an N δ ‐acetylornithine decarboxylase" . Journal of Integrative Plant Biology . 62 (5): 601–613.
doi :
10.1111/jipb.12821 .
ISSN
1672-9072 .
PMID
31081586 .
S2CID
153308462 .
^ Huang, Tengfang; Jander, Georg (2017).
"Abscisic acid-regulated protein degradation causes osmotic stress-induced accumulation of branched-chain amino acids in Arabidopsis thaliana" . Planta . 246 (4): 737–747.
doi :
10.1007/s00425-017-2727-3 .
ISSN
0032-0935 .
PMID
28668976 .
S2CID
253892798 .
^ Lou, Yann-Ru; Bor, Melike; Yan, Jian; Preuss, Aileen S; Jander, Georg (2016).
"Arabidopsis NATA1 acetylates putrescine and decreases defense-related hydrogen peroxide accumulation" . Plant Physiology . 171 (2): 1443–1455.
doi :
10.1104/pp.16.00446 .
ISSN
0032-0889 .
PMC
4902623 .
PMID
27208290 .
^ Züst, Tobias; Strickler, Susan R; Powell, Adrian F; Mabry, Makenzie E; An, Hong; Mirzaei, Mahdieh; York, Thomas; Holland, Cynthia K; Kumar, Pavan; Erb, Matthias; Petschenka, Georg; Gómez, José-María; Perfectti, Francisco; Müller, Caroline; Pires, J Chris (2020-04-07).
"Independent evolution of ancestral and novel defenses in a genus of toxic plants (Erysimum, Brassicaceae)" . eLife . 9 : e51712.
doi :
10.7554/eLife.51712 .
ISSN
2050-084X .
PMC
7180059 .
PMID
32252891 .
^ Mirzaei, Mahdieh; Züst, Tobias; Younkin, Gordon C.; Hastings, Amy P.; Alani, Martin L.; Agrawal, Anurag A.; Jander, Georg (2020).
"Less Is More: a Mutation in the Chemical Defense Pathway of Erysimum cheiranthoides (Brassicaceae) Reduces Total Cardenolide Abundance but Increases Resistance to Insect Herbivores" . Journal of Chemical Ecology . 46 (11–12): 1131–1143.
doi :
10.1007/s10886-020-01225-y .
ISSN
0098-0331 .
PMID
33180277 .
S2CID
218539206 .
^ Haas, Michael J.
"Wallflowers Could Lead to New Drugs" . Boyce Thompson Institute . Retrieved 2022-12-24 .
^ Alani, Martin L.; Younkin, Gordon C.; Mirzaei, Mahdieh; Kumar, Pavan; Jander, Georg (2021).
"Acropetal and basipetal cardenolide transport in Erysimum cheiranthoides (wormseed wallflower)" . Phytochemistry . 192 : 112965.
doi :
10.1016/j.phytochem.2021.112965 .
PMC
8655687 .
PMID
34610557 .
^ Feng, Honglin; Acosta-Gamboa, Lucia; Kruse, Lars H.; Tracy, Jake D.; Chung, Seung Ho; Nava Fereira, Alba Ruth; Shakir, Sara; Xu, Hongxing; Sunter, Garry; Gore, Michael A.; Casteel, Clare L.; Moghe, Gaurav D.; Jander, Georg (2022).
"Acylsugars protect Nicotiana benthamiana against insect herbivory and desiccation" . Plant Molecular Biology . 109 (4–5): 505–522.
doi :
10.1007/s11103-021-01191-3 .
hdl :
2268/295578 .
ISSN
0167-4412 .
PMID
34586580 .
S2CID
254935688 .
^ Chung, Seung Ho; Bigham, Mahdiyeh; Lappe, Ryan R.; Chan, Barry; Nagalakshmi, Ugrappa; Whitham, Steven A.; Dinesh‐Kumar, Savithramma P.; Jander, Georg (2021).
"A sugarcane mosaic virus vector for rapid in planta screening of proteins that inhibit the growth of insect herbivores" . Plant Biotechnology Journal . 19 (9): 1713–1724.
doi :
10.1111/pbi.13585 .
ISSN
1467-7644 .
PMC
8428830 .
PMID
33763921 .
^ Rauf, I.; Asif, M.; Amin, I.; Naqvi, R. Z.; Umer, N.; Mansoor, S.; Jander, G. (2019).
"Silencing cathepsin L expression reduces Myzus persicae protein content and the nutritional value as prey for Coccinella septempunctata" . Insect Molecular Biology . 28 (6): 785–797.
doi :
10.1111/imb.12589 .
ISSN
0962-1075 .
PMID
30980445 .
S2CID
91978669 .
^ Chen, Wenbo; Shakir, Sara; Bigham, Mahdiyeh; Richter, Annett; Fei, Zhangjun; Jander, Georg (2019-04-01).
"Genome sequence of the corn leaf aphid ( Rhopalosiphum maidis Fitch)" . GigaScience . 8 (4).
doi :
10.1093/gigascience/giz033 .
ISSN
2047-217X .
PMC
6451198 .
PMID
30953568 .
^ Haribal, Meena; Jander, Georg (2015-12-01).
"Stable isotope studies reveal pathways for the incorporation of non-essential amino acids in Acyrthosiphon pisum (pea aphids)" . Journal of Experimental Biology . 218 (23): 3797–3806.
doi :
10.1242/jeb.129189 .
ISSN
1477-9145 .
PMID
26632455 .
S2CID
37641651 .
^ Tzin, Vered; Lindsay, Penelope L.; Christensen, Shawn A.; Meihls, Lisa N.; Blue, Levi B.; Jander, Georg (2015).
"Genetic mapping shows intraspecific variation and transgressive segregation for caterpillar‐induced aphid resistance in maize" . Molecular Ecology . 24 (22): 5739–5750.
doi :
10.1111/mec.13418 .
ISSN
0962-1083 .
PMID
26462033 .
S2CID
206182798 .
^ Casteel, Clare L.; De Alwis, Manori; Bak, Aurélie; Dong, Haili; Whitham, Steven A.; Jander, Georg (2015).
"Disruption of Ethylene Responses by Turnip mosaic virus Mediates Suppression of Plant Defense against the Green Peach Aphid Vector" . Plant Physiology . 169 (1): 209–218.
doi :
10.1104/pp.15.00332 .
ISSN
0032-0889 .
PMC
4577379 .
PMID
26091820 .
^ Ramsey, John S.; Elzinga, Dezi A.; Sarkar, Pooja; Xin, Yi-Ran; Ghanim, Murad; Jander, Georg (2014).
"Adaptation to Nicotine Feeding in Myzus persicae" . Journal of Chemical Ecology . 40 (8): 869–877.
doi :
10.1007/s10886-014-0482-5 .
ISSN
0098-0331 .
PMC
4170791 .
PMID
25082103 .
^ Elzinga, Dezi A.; De Vos, Martin; Jander, Georg (2014).
"Suppression of Plant Defenses by a Myzus persicae (Green Peach Aphid) Salivary Effector Protein" . Molecular Plant-Microbe Interactions . 27 (7): 747–756.
doi :
10.1094/MPMI-01-14-0018-R .
ISSN
0894-0282 .
PMC
4170801 .
PMID
24654979 .
^ Waldron, Patricia.
"Fearless Aphids Ignore Warnings, Get Eaten by Ladybugs" . Boyce Thompson Institute . Retrieved 2022-12-24 .
^
"About Us" . Elo Life Systems . Retrieved 2022-12-24 .
^
"Zymtronix" . zymtronix.com . Retrieved 2022-12-24 .
^
"Dezi Elzinga" . Dezi Elzinga . 2022-12-24.
^
"John Ramsey : USDA ARS" . www.ars.usda.gov . Retrieved 2022-12-24 .
^ Detrick, Scott (2022-10-19).
"Dr. Yann-Ru Lou" . Department of Plant Biology . Retrieved 2022-12-24 .
^
"Principal Investigators at AGIS" . Principal Investigators at AGIS . 2022-12-24.
^
"BTI Internships" . Boyce Thompson Institute . Retrieved 2022-12-24 .
^
"NSF Award Search: Award # 1850796 - REU Site: Plant Genome Research" . nsf.gov . Retrieved 2022-12-24 .
^
"Recent Awards" . portal.nifa.usda.gov . Retrieved 2022-12-24 .
^
"Adam-Steinbrenner | UW Biology" . www.biology.washington.edu . Retrieved 2022-12-24 .
^
"Kaitlin Gold" . CALS . Retrieved 2022-12-24 .
^
"Inari: Home" . inari.com . Retrieved 2022-12-24 .
^
"Intern Profiles" . Boyce Thompson Institute . Retrieved 2022-12-24 .
^
"Friedrich Wilhelm Bessel Research Award - Research in Germany" . www.research-in-germany.org . Retrieved 2022-12-24 .
^
"AAAS Members Elected as Fellows | American Association for the Advancement of Science (AAAS)" . www.aaas.org . Retrieved 2022-12-24 .
^
"Fellow of ASPB" . American Society of Plant Biologists . Retrieved 2022-12-24 .
International National Academics Other