Glutathione S-transferase omega-1 is an
enzyme that in humans is encoded by the GSTO1gene.[5][6][7]
This gene encodes a member of the theta class glutathione S-transferase-like (GSTTL) protein family. In mouse, the encoded protein acts as a small stress response
protein, likely involved in cellular redox homeostasis.[7] This protein has
dehydroascorbate reductase activity and may function in the
glutathione-ascorbate cycle as part of
antioxidant metabolism.[8]
Matoba R, Okubo K, Hori N, Atsushi F, Kenichi M (1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199–207.
doi:
10.1016/0378-1119(94)90293-3.
PMID8076819.
Tanaka-Kagawa T, Jinno H, Hasegawa T, Makino Y, Seko Y, Hanioka N, et al. (2003). "Functional characterization of two variant human GSTO 1-1s (Ala140Asp and Thr217Asn)". Biochem. Biophys. Res. Commun. 301 (2): 516–20.
doi:
10.1016/S0006-291X(02)03066-8.
PMID12565892.
Kölsch H, Linnebank M, Lütjohann D, Jessen F, Wüllner U, Harbrecht U, et al. (2005). "Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke". Neurology. 63 (12): 2255–60.
doi:
10.1212/01.wnl.0000147294.29309.47.
PMID15623683.
S2CID21431373.
Ozturk A, Desai PP, Minster RL, Dekosky ST, Kamboh MI (2005). "Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer's disease". Neurobiol. Aging. 26 (8): 1161–5.
doi:
10.1016/j.neurobiolaging.2004.11.001.
PMID15917099.
S2CID10878355.
Fujihara J, Kunito T, Takeshita H (2007). "Frequency of two human glutathione-S-transferase omega-1 polymorphisms (E155 deletion and E208K) in Ovambo and Japanese populations using the PCR-based genotyping method". Clin. Chem. Lab. Med. 45 (5): 621–4.
doi:
10.1515/CCLM.2007.128.
PMID17484623.
S2CID1553700.
Glutathione S-transferase omega-1 is an
enzyme that in humans is encoded by the GSTO1gene.[5][6][7]
This gene encodes a member of the theta class glutathione S-transferase-like (GSTTL) protein family. In mouse, the encoded protein acts as a small stress response
protein, likely involved in cellular redox homeostasis.[7] This protein has
dehydroascorbate reductase activity and may function in the
glutathione-ascorbate cycle as part of
antioxidant metabolism.[8]
Matoba R, Okubo K, Hori N, Atsushi F, Kenichi M (1994). "The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression". Gene. 146 (2): 199–207.
doi:
10.1016/0378-1119(94)90293-3.
PMID8076819.
Tanaka-Kagawa T, Jinno H, Hasegawa T, Makino Y, Seko Y, Hanioka N, et al. (2003). "Functional characterization of two variant human GSTO 1-1s (Ala140Asp and Thr217Asn)". Biochem. Biophys. Res. Commun. 301 (2): 516–20.
doi:
10.1016/S0006-291X(02)03066-8.
PMID12565892.
Kölsch H, Linnebank M, Lütjohann D, Jessen F, Wüllner U, Harbrecht U, et al. (2005). "Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke". Neurology. 63 (12): 2255–60.
doi:
10.1212/01.wnl.0000147294.29309.47.
PMID15623683.
S2CID21431373.
Ozturk A, Desai PP, Minster RL, Dekosky ST, Kamboh MI (2005). "Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer's disease". Neurobiol. Aging. 26 (8): 1161–5.
doi:
10.1016/j.neurobiolaging.2004.11.001.
PMID15917099.
S2CID10878355.
Fujihara J, Kunito T, Takeshita H (2007). "Frequency of two human glutathione-S-transferase omega-1 polymorphisms (E155 deletion and E208K) in Ovambo and Japanese populations using the PCR-based genotyping method". Clin. Chem. Lab. Med. 45 (5): 621–4.
doi:
10.1515/CCLM.2007.128.
PMID17484623.
S2CID1553700.