From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
HASPIN
Available structures
PDB Ortholog search:
PDBe
RCSB List of PDB id codes
2VUW ,
2WB8 ,
3DLZ ,
3E7V ,
3F2N ,
3FMD ,
3IQ7 ,
4OUC ,
4QTC ,
5HTC ,
5HTB
Identifiers
Aliases
HASPIN , GSG2, germ cell associated 2, haspin, histone H3 associated protein kinaseExternal IDs
OMIM :
609240 ;
MGI :
1194498 ;
HomoloGene :
49236 ;
GeneCards :
HASPIN ;
OMA :
HASPIN - orthologs
Wikidata
Serine/threonine-protein kinase haspin is an
enzyme that in humans is encoded by the GSG2
gene .
[5]
Dai J, Sullivan BA, Higgins JM (2007).
"Regulation of mitotic chromosome cohesion by Haspin and Aurora B." Dev. Cell . 11 (5): 741–50.
doi :
10.1016/j.devcel.2006.09.018 .
PMID
17084365 .
Nousiainen M, Silljé HH, Sauer G, et al. (2006).
"Phosphoproteome analysis of the human mitotic spindle" . Proc. Natl. Acad. Sci. U.S.A . 103 (14): 5391–6.
Bibcode :
2006PNAS..103.5391N .
doi :
10.1073/pnas.0507066103 .
PMC
1459365 .
PMID
16565220 .
Dai J, Sultan S, Taylor SS, Higgins JM (2005).
"The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment" . Genes Dev . 19 (4): 472–88.
doi :
10.1101/gad.1267105 .
PMC
548948 .
PMID
15681610 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Higgins JM (2001). "The Haspin gene: location in an intron of the integrin alphaE gene, associated transcription of an integrin alphaE-derived RNA and expression in diploid as well as haploid cells". Gene . 267 (1): 55–69.
doi :
10.1016/S0378-1119(01)00387-0 .
PMID
11311556 .
Tanaka H, Iguchi N, Nakamura Y, et al. (2001).
"Cloning and characterization of human haspin gene encoding haploid germ cell-specific nuclear protein kinase" . Mol. Hum. Reprod . 7 (3): 211–8.
doi :
10.1093/molehr/7.3.211 .
PMID
11228240 .