GPO may refer to:

Government and politics

• General Post Office, Dublin
• General Post Office, in Britain
• Social Security Government Pension Offset, a provision reducing benefits
• Government Pharmaceutical Organization, a Thai state enterprise
• Government Press Office (Israel)
• Green Party of Ontario, Canada
• United States Government Publishing Office
• Group Purchasing Organization

Places

• Gospel Oak railway station, in London, England
• Guam Premier Outlets, a shopping mall in Guam
• Indore G.P.O., a residential area in Indore, India
• General Pico Airport, in Argentina, IATA code

Science and technology

• Giant Pacific Octopus
• Group Policy Object
• General Purpose Outlet, mains socket in Australia
• General Purpose Output, an uncommitted digital signal pin on an integrated circuit or electronic circuit board used as an output and controllable by the user at runtime.

Other uses

• Generalplan Ost, a Nazi genocide plan in occupied territories
• General Post Office (disambiguation)
• Group purchasing organization
• Gun Position Officer, usually a lieutenant, responsible for the technical control of an artillery battery in the United Kingdom and Commonwealth forces

This disambiguation page lists articles associated with the title GPO.
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• Grand Piece Online, a Roblox videogame based on One Piece