Serpin A9 also known as centerin or GCET1 is a
protein that in humans is encoded by the SERPINA9gene located on
chromosome 14q32.1.[5] Serpin A9 is a member of the
serpin family of serine protease inhibitors.
Function
The expression of SERPINA9 is restricted to
germinal centerB cells and
lymphoid malignancies. SERPINA9 is likely to function in vivo in the germinal center as an efficient inhibitor of trypsin-like proteases.[6][7][8]
Namciu SJ, Friedman RD, Marsden MD, et al. (2004). "Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1". Mamm. Genome. 15 (3): 162–78.
doi:
10.1007/s00335-003-2311-y.
PMID15014966.
S2CID8594824.
External links
The
MEROPS online database for peptidases and their inhibitors:
I04.082
Serpin A9 also known as centerin or GCET1 is a
protein that in humans is encoded by the SERPINA9gene located on
chromosome 14q32.1.[5] Serpin A9 is a member of the
serpin family of serine protease inhibitors.
Function
The expression of SERPINA9 is restricted to
germinal centerB cells and
lymphoid malignancies. SERPINA9 is likely to function in vivo in the germinal center as an efficient inhibitor of trypsin-like proteases.[6][7][8]
Namciu SJ, Friedman RD, Marsden MD, et al. (2004). "Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1". Mamm. Genome. 15 (3): 162–78.
doi:
10.1007/s00335-003-2311-y.
PMID15014966.
S2CID8594824.
External links
The
MEROPS online database for peptidases and their inhibitors:
I04.082