GRB2 associated binding protein 3 is a
protein that in humans is encoded by the GAB3
gene.
[5]
Function
This gene is a member of the
GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several
growth factor and
cytokine signaling pathways, and they contain a
pleckstrin homology domain, and bind
SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates
macrophage differentiation.
Alternative splicing results in multiple transcript variants.
GRB2 associated binding protein 3 is a
protein that in humans is encoded by the GAB3
gene.
[5]
Function
This gene is a member of the
GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several
growth factor and
cytokine signaling pathways, and they contain a
pleckstrin homology domain, and bind
SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates
macrophage differentiation.
Alternative splicing results in multiple transcript variants.