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GA-cis | |
---|---|
![]() Consensus
secondary structure and
sequence conservation of GA-cis RNA | |
Identifiers | |
Symbol | GA-cis |
Rfam | RF02987 |
Other data | |
RNA type | Gene; sRNA |
SO | SO:0001263 |
PDB structures | PDBe |
The GA-cis RNA motif is a conserved RNA structure that was discovered by bioinformatics. [1] GA-cis motif RNAs are found in one species classified within the phylum Bacillota: specifically, there are 9 predicted copies in Coprocuccus eutactus ATCC 27759.
GA-cis RNAs are generally located in the 5' untranslated regions of protein-coding genes. Indeed, the RNAs are upstream of multiple genes that encode non- homologous proteins. If all examples of the RNA were upstream of homologous genes, there is the possibility that the RNAs were conserved in that position simply by inheritance. The non-homology of the genes downstream of COG2908 RNAs makes this scenario less likely. This evidence suggests that GA-cis RNAs function as cis-regulatory elements. However, due to some cases where a GA-cis RNA is not immediately upstream of a gene makes this hypothesis tentative.
The GA-cis RNA motif is named because of the frequent occurrence of conserved GpA di- nucleotides in its sequence, and its locations that are typical of cis-regulatory elements.
![]() | This article has multiple issues. Please help
improve it or discuss these issues on the
talk page. (
Learn how and when to remove these template messages)
|
GA-cis | |
---|---|
![]() Consensus
secondary structure and
sequence conservation of GA-cis RNA | |
Identifiers | |
Symbol | GA-cis |
Rfam | RF02987 |
Other data | |
RNA type | Gene; sRNA |
SO | SO:0001263 |
PDB structures | PDBe |
The GA-cis RNA motif is a conserved RNA structure that was discovered by bioinformatics. [1] GA-cis motif RNAs are found in one species classified within the phylum Bacillota: specifically, there are 9 predicted copies in Coprocuccus eutactus ATCC 27759.
GA-cis RNAs are generally located in the 5' untranslated regions of protein-coding genes. Indeed, the RNAs are upstream of multiple genes that encode non- homologous proteins. If all examples of the RNA were upstream of homologous genes, there is the possibility that the RNAs were conserved in that position simply by inheritance. The non-homology of the genes downstream of COG2908 RNAs makes this scenario less likely. This evidence suggests that GA-cis RNAs function as cis-regulatory elements. However, due to some cases where a GA-cis RNA is not immediately upstream of a gene makes this hypothesis tentative.
The GA-cis RNA motif is named because of the frequent occurrence of conserved GpA di- nucleotides in its sequence, and its locations that are typical of cis-regulatory elements.