First strike most commonly refers to:

• First strike (nuclear strategy)
• Preemptive war

First strike may also refer to:

• First Strike (1979 film), a United States Air Force documentary
• First Strike (1996 film), a Hong Kong action film starring Jackie Chan
• Tales of Vesperia: The First Strike, a 2009 Japanese animated film
• "First Strike" (Stargate Atlantis), a 2007 TV episode

• First Strike (DC Comics), a fictional team of superheroes
• First Strike (IDW Publishing), a 2017 crossover event set in the Hasbro Universe
• Halo: First Strike, a 2003 science fiction novel by Eric Nylund, based on the video game series
• First Strike, a 1979 novel by Douglas Terman

• First Strike (album), a 1983 album by Cobra
• First strike (coinage), the first coins struck from a new set of dies

• First use (disambiguation)
• First Blood (disambiguation)
• Strike (disambiguation)

This disambiguation page lists articles associated with the title First strike.
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