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Summary
| Description |
English: a. Each row represents a CpG probe (binding to each CpG site where DNA demethylation can occur), and each column represents an individual's sample. The color scale from blue to red indicates the DNA methylation level, ranging from 0 (no methylation) to 1 (fully methylated). The episignatures of pathogenic TET3 mutations display DNA hypermethylation in comparison to matched and family controls.
b. Multidimensional scaling can assist in stratifying TET3 variants of uncertain significance (VUS) as either pathogenic or benign. Note: bi-allelic (BA); mono-allelic (MA) |
| Date | |
| Source |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576018/bin/41525_2021_256_MOESM1_ESM.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576018/ |
| Author | Levy et al. |
Licensing
This file is licensed under the
Creative Commons
Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 03:05, 4 February 2024 |
| 2,052 × 1,755 (846 KB) | Strange Orange | Uploaded a work by Levy et al. from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576018/bin/41525_2021_256_MOESM1_ESM.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576018/ with UploadWizard |
File usage
The following pages on the English Wikipedia use this file (pages on other projects are not listed):
Size of this preview:
701 × 600 pixels. Other resolutions:
281 × 240 pixels |
561 × 480 pixels |
898 × 768 pixels |
1,197 × 1,024 pixels |
2,052 × 1,755 pixels.
Original file (2,052 × 1,755 pixels, file size: 846 KB, MIME type: image/png)
| This is a file from the
Wikimedia Commons. Information from its
description page there is shown below. Commons is a freely licensed media file repository. You can help. |
Summary
| Description |
English: a. Each row represents a CpG probe (binding to each CpG site where DNA demethylation can occur), and each column represents an individual's sample. The color scale from blue to red indicates the DNA methylation level, ranging from 0 (no methylation) to 1 (fully methylated). The episignatures of pathogenic TET3 mutations display DNA hypermethylation in comparison to matched and family controls.
b. Multidimensional scaling can assist in stratifying TET3 variants of uncertain significance (VUS) as either pathogenic or benign. Note: bi-allelic (BA); mono-allelic (MA) |
| Date | |
| Source |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576018/bin/41525_2021_256_MOESM1_ESM.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576018/ |
| Author | Levy et al. |
Licensing
This file is licensed under the
Creative Commons
Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
File history
Click on a date/time to view the file as it appeared at that time.
| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 03:05, 4 February 2024 |
| 2,052 × 1,755 (846 KB) | Strange Orange | Uploaded a work by Levy et al. from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576018/bin/41525_2021_256_MOESM1_ESM.pdf https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8576018/ with UploadWizard |
File usage
The following pages on the English Wikipedia use this file (pages on other projects are not listed):