| Combination of | |
|---|---|
| Fenofibrate | Fibrate |
| Simvastatin | Statin |
| Clinical data | |
| Trade names | Cholib |
|
Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | |
| KEGG | |
Fenofibrate/simvastatin, sold under the brand name Cholib, is a fixed-dose combination medication used to treat abnormal blood lipid levels when used in combination with a low-fat diet and exercise. [1] It contains fenofibrate and simvastatin. [1]
It was approved for use in the European Union in August 2013. [1]
Medical uses
Fenofibrate/simvastatin is indicated as adjunctive therapy to diet and exercise in high cardiovascular risk adults with mixed dyslipidemia to reduce triglycerides and increase HDL C levels when LDL C levels are adequately controlled with the corresponding dose of simvastatin monotherapy. [1]
Adverse effects
References
- ^ a b c d e "Cholib EPAR". European Medicines Agency (EMA). 5 March 2020. Archived from the original on 12 November 2020. Retrieved 5 March 2020. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
Further reading
- Filippatos TD, Elisaf MS (2015). "Safety considerations with fenofibrate/simvastatin combination". Expert Opin Drug Saf. 14 (9): 1481–93. doi: 10.1517/14740338.2015.1056778. PMID 26134595. S2CID 207488283.
- Tarantino N, Santoro F, De Gennaro L, Correale M, Guastafierro F, Gaglione A, et al. (2017).
"Fenofibrate/simvastatin fixed-dose combination in the treatment of mixed dyslipidemia: safety, efficacy, and place in therapy". Vasc Health Risk Manag. 13: 29–41.
doi:
10.2147/VHRM.S95044.
PMC
5317328.
PMID
28243111.
{{ cite journal}}: CS1 maint: overridden setting ( link)
 | This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it. |
- 2-Methyl-2-phenoxypropanoic acid derivatives
- 17β-Hydroxysteroid dehydrogenase inhibitors
- Benzophenones
- Carboxylate esters
- Chloroarenes
- Combination lipid-lowering drugs
- Isopropyl esters
- Lactones
- Neuroprotective agents
- Prodrugs
- Secondary alcohols
- Statins
- Tetrahydropyrans
- Cardiovascular system drug stubs
| Combination of | |
|---|---|
| Fenofibrate | Fibrate |
| Simvastatin | Statin |
| Clinical data | |
| Trade names | Cholib |
|
Routes of administration | By mouth |
| ATC code | |
| Legal status | |
| Legal status |
|
| Identifiers | |
| CAS Number | |
| KEGG | |
Fenofibrate/simvastatin, sold under the brand name Cholib, is a fixed-dose combination medication used to treat abnormal blood lipid levels when used in combination with a low-fat diet and exercise. [1] It contains fenofibrate and simvastatin. [1]
It was approved for use in the European Union in August 2013. [1]
Medical uses
Fenofibrate/simvastatin is indicated as adjunctive therapy to diet and exercise in high cardiovascular risk adults with mixed dyslipidemia to reduce triglycerides and increase HDL C levels when LDL C levels are adequately controlled with the corresponding dose of simvastatin monotherapy. [1]
Adverse effects
References
- ^ a b c d e "Cholib EPAR". European Medicines Agency (EMA). 5 March 2020. Archived from the original on 12 November 2020. Retrieved 5 March 2020. Text was copied from this source which is copyright European Medicines Agency. Reproduction is authorized provided the source is acknowledged.
Further reading
- Filippatos TD, Elisaf MS (2015). "Safety considerations with fenofibrate/simvastatin combination". Expert Opin Drug Saf. 14 (9): 1481–93. doi: 10.1517/14740338.2015.1056778. PMID 26134595. S2CID 207488283.
- Tarantino N, Santoro F, De Gennaro L, Correale M, Guastafierro F, Gaglione A, et al. (2017).
"Fenofibrate/simvastatin fixed-dose combination in the treatment of mixed dyslipidemia: safety, efficacy, and place in therapy". Vasc Health Risk Manag. 13: 29–41.
doi:
10.2147/VHRM.S95044.
PMC
5317328.
PMID
28243111.
{{ cite journal}}: CS1 maint: overridden setting ( link)
|
| This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it. |
- 2-Methyl-2-phenoxypropanoic acid derivatives
- 17β-Hydroxysteroid dehydrogenase inhibitors
- Benzophenones
- Carboxylate esters
- Chloroarenes
- Combination lipid-lowering drugs
- Isopropyl esters
- Lactones
- Neuroprotective agents
- Prodrugs
- Secondary alcohols
- Statins
- Tetrahydropyrans
- Cardiovascular system drug stubs