Farrowia | |
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Scientific classification | |
Kingdom: | |
Division: | |
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Genus: | Farrowia |
Farrowia is a genus of fungi within the Chaetomiaceae family. [1]
In 1975, Hawksworth suggested a novel genus for F. seminuda, F. longicola, and F. malaysiensis. [2] These species were distinguished from other Chaetomium species by their long-necked ascomata and production of anamorphs similar to Botryotrichum. [2] However, this categorization has been controversial since its inception. [3] [4] [5] In 2001, a molecular phylogenetic study using rRNA sequence data did not support the separation of Farrowia and Chaetomium. [6]
Widden, in 1986, suggested that Farrowia seminuda and Botryotrichum piluliferum are the teleomorph and anamorph of the same organism based on their preference for coniferous soils and visual indistinguishability. [7]
Perithecia are subglobose (imperfectly spherical), with straight, unbranched lateral and terminal hairs. [2] The terminal hairs fuse to form a neck-like structure, potentially rudimentary. [2] Pedestal-like rhizoidal bases are usually present. Farrowia forms asci which are clavate (club-shaped) and deliquesce before ascospores mature. [2] The ascospores are lemoniform (lemon-shaped), biapiculate, and are not ornamented. [2] F. malaysiensiensis is reported having a longer neck than the other two species in this genus. [3] [8]
In media cultures, reddish brown pigments are produced only in the presence of contaminants. [2]
Species are widespread across tropical and temperate areas. [7] [8] It is most commonly found in soil, although F. longicola has been found in leaf litter [5] and freshwater. [8]
Novel interleukin inhibitors were isolated from Farrowia broths in 2003. [9] These compounds were named EI-1941-1 and EI-1941-2. The enzymes they specifically inhibit are elastase and cathepsin B. [9] EI-1941-2 is degraded by the presence of cysteine, but EI-1941-1 is not. [9] Further study of these ICE inhibitors could lead to new synthetic anti-inflammatory agents.
{{
cite book}}
: CS1 maint: multiple names: authors list (
link)
Farrowia | |
---|---|
Scientific classification | |
Kingdom: | |
Division: | |
Subdivision: | |
Class: | |
Order: | |
Family: | |
Genus: | Farrowia |
Farrowia is a genus of fungi within the Chaetomiaceae family. [1]
In 1975, Hawksworth suggested a novel genus for F. seminuda, F. longicola, and F. malaysiensis. [2] These species were distinguished from other Chaetomium species by their long-necked ascomata and production of anamorphs similar to Botryotrichum. [2] However, this categorization has been controversial since its inception. [3] [4] [5] In 2001, a molecular phylogenetic study using rRNA sequence data did not support the separation of Farrowia and Chaetomium. [6]
Widden, in 1986, suggested that Farrowia seminuda and Botryotrichum piluliferum are the teleomorph and anamorph of the same organism based on their preference for coniferous soils and visual indistinguishability. [7]
Perithecia are subglobose (imperfectly spherical), with straight, unbranched lateral and terminal hairs. [2] The terminal hairs fuse to form a neck-like structure, potentially rudimentary. [2] Pedestal-like rhizoidal bases are usually present. Farrowia forms asci which are clavate (club-shaped) and deliquesce before ascospores mature. [2] The ascospores are lemoniform (lemon-shaped), biapiculate, and are not ornamented. [2] F. malaysiensiensis is reported having a longer neck than the other two species in this genus. [3] [8]
In media cultures, reddish brown pigments are produced only in the presence of contaminants. [2]
Species are widespread across tropical and temperate areas. [7] [8] It is most commonly found in soil, although F. longicola has been found in leaf litter [5] and freshwater. [8]
Novel interleukin inhibitors were isolated from Farrowia broths in 2003. [9] These compounds were named EI-1941-1 and EI-1941-2. The enzymes they specifically inhibit are elastase and cathepsin B. [9] EI-1941-2 is degraded by the presence of cysteine, but EI-1941-1 is not. [9] Further study of these ICE inhibitors could lead to new synthetic anti-inflammatory agents.
{{
cite book}}
: CS1 maint: multiple names: authors list (
link)