3'-5' exoribonuclease CSL4 homolog is an
enzyme that in humans is encoded by the EXOSC1gene.[5][6][7]
This gene encodes a core component of the
exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.[7]
Interactions
Exosome component 1 has been shown to
interact with:
^
abcRaijmakers R, Egberts WV, van Venrooij WJ, Pruijn GJ (Nov 2002). "Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring". J. Mol. Biol. 323 (4): 653–63.
doi:
10.1016/s0022-2836(02)00947-6.
hdl:2066/186665.
PMID12419256.
Raijmakers R, Egberts WV, van Venrooij WJ, Pruijn GJ (2002). "Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring". J. Mol. Biol. 323 (4): 653–63.
doi:
10.1016/S0022-2836(02)00947-6.
hdl:2066/186665.
PMID12419256.
3'-5' exoribonuclease CSL4 homolog is an
enzyme that in humans is encoded by the EXOSC1gene.[5][6][7]
This gene encodes a core component of the
exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.[7]
Interactions
Exosome component 1 has been shown to
interact with:
^
abcRaijmakers R, Egberts WV, van Venrooij WJ, Pruijn GJ (Nov 2002). "Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring". J. Mol. Biol. 323 (4): 653–63.
doi:
10.1016/s0022-2836(02)00947-6.
hdl:2066/186665.
PMID12419256.
Raijmakers R, Egberts WV, van Venrooij WJ, Pruijn GJ (2002). "Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring". J. Mol. Biol. 323 (4): 653–63.
doi:
10.1016/S0022-2836(02)00947-6.
hdl:2066/186665.
PMID12419256.