Names | |
---|---|
IUPAC name
5β,8α,9β,10α,13α-Kaur-16-en-18-oic acid
| |
Systematic IUPAC name
(4R,4aS,6aS,9R,11aR,11bS)-4,11b-Dimethyl-8-methylidenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid | |
Other names
| |
Identifiers | |
3D model (
JSmol)
|
|
10784819 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
KEGG | |
PubChem
CID
|
|
UNII | |
| |
| |
Properties | |
C20H30O2 | |
Molar mass | 302.458 g·mol−1 |
Pharmacology | |
M09AX05 ( WHO) | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Kaurenoic acid (ent-kaur-16-en-19-oic acid or kauren-19-oic acid) is a diterpene with antibacterial activity against Gram-positive bacteria. However its low solubility and blood lytic activity on erythrocytes might make it a poor pharmaceutical candidate. [1] Kaurenoic acid also has uterine relaxant activity via calcium blockade and opening ATP-sensitive potassium channels.
Kaurenoic acid is found in several plants such as Copaifera. It is a potential biomarker for the presence of sunflower in foods. [2]
Kaurenoic acid has been studied for its medicinal properties and seems to have anti-inflammatory, antiulcerogenic, antitumor, antinociceptive, antimelanoma, antitilipoperoxidation, antioxidant and antimicrobial properties. [3]
Kaurenoic acid decreases leukocyte migration. It seems to inhibit histamine and serotonin pathways, in addition to antiprotozoal activities against Trypanosoma cruzi [4] [5] and Leishmania amazonensis. [6]
Names | |
---|---|
IUPAC name
5β,8α,9β,10α,13α-Kaur-16-en-18-oic acid
| |
Systematic IUPAC name
(4R,4aS,6aS,9R,11aR,11bS)-4,11b-Dimethyl-8-methylidenetetradecahydro-6a,9-methanocyclohepta[a]naphthalene-4-carboxylic acid | |
Other names
| |
Identifiers | |
3D model (
JSmol)
|
|
10784819 | |
ChEBI | |
ChEMBL | |
ChemSpider | |
KEGG | |
PubChem
CID
|
|
UNII | |
| |
| |
Properties | |
C20H30O2 | |
Molar mass | 302.458 g·mol−1 |
Pharmacology | |
M09AX05 ( WHO) | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
|
Kaurenoic acid (ent-kaur-16-en-19-oic acid or kauren-19-oic acid) is a diterpene with antibacterial activity against Gram-positive bacteria. However its low solubility and blood lytic activity on erythrocytes might make it a poor pharmaceutical candidate. [1] Kaurenoic acid also has uterine relaxant activity via calcium blockade and opening ATP-sensitive potassium channels.
Kaurenoic acid is found in several plants such as Copaifera. It is a potential biomarker for the presence of sunflower in foods. [2]
Kaurenoic acid has been studied for its medicinal properties and seems to have anti-inflammatory, antiulcerogenic, antitumor, antinociceptive, antimelanoma, antitilipoperoxidation, antioxidant and antimicrobial properties. [3]
Kaurenoic acid decreases leukocyte migration. It seems to inhibit histamine and serotonin pathways, in addition to antiprotozoal activities against Trypanosoma cruzi [4] [5] and Leishmania amazonensis. [6]