Chymotrypsin C, also known as caldecrin or elastase 4, is an
enzyme that in humans is encoded by the CTRCgene.[5][6]
Function
Chymotrypsin C is a member of the
peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has
chymotrypsin-like
protease activity.[5]
Stavridi ES, O'Malley K, Lukacs CM, et al. (1996). "Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis". Biochemistry. 35 (33): 10608–15.
doi:
10.1021/bi9605806.
PMID8718849.
Chang MC, Chang YT, Wei SC, et al. (2009). "Association of novel chymotrypsin C gene variations and haplotypes in patients with chronic pancreatitis in Chinese in Taiwan". Pancreatology. 9 (3): 287–92.
doi:
10.1159/000199437.
PMID19407484.
S2CID25853177.
Yoshino-Yasuda I, Kobayashi K, Akiyama M, et al. (1998). "Caldecrin is a novel-type serine protease expressed in pancreas, but its homologue, elastase IV, is an artifact during cloning derived from caldecrin gene". J. Biochem. 123 (3): 546–54.
doi:
10.1093/oxfordjournals.jbchem.a021971.
PMID9538241.
Derikx MH, Szmola R, te Morsche RH, et al. (2009). "Tropical calcific pancreatitis and its association with CTRC and SPINK1 (p.N34S) variants". Eur J Gastroenterol Hepatol. 21 (8): 889–94.
doi:
10.1097/MEG.0b013e32832183cf.
PMID19404200.
S2CID22812634.
Chymotrypsin C, also known as caldecrin or elastase 4, is an
enzyme that in humans is encoded by the CTRCgene.[5][6]
Function
Chymotrypsin C is a member of the
peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has
chymotrypsin-like
protease activity.[5]
Stavridi ES, O'Malley K, Lukacs CM, et al. (1996). "Structural change in alpha-chymotrypsin induced by complexation with alpha 1-antichymotrypsin as seen by enhanced sensitivity to proteolysis". Biochemistry. 35 (33): 10608–15.
doi:
10.1021/bi9605806.
PMID8718849.
Chang MC, Chang YT, Wei SC, et al. (2009). "Association of novel chymotrypsin C gene variations and haplotypes in patients with chronic pancreatitis in Chinese in Taiwan". Pancreatology. 9 (3): 287–92.
doi:
10.1159/000199437.
PMID19407484.
S2CID25853177.
Yoshino-Yasuda I, Kobayashi K, Akiyama M, et al. (1998). "Caldecrin is a novel-type serine protease expressed in pancreas, but its homologue, elastase IV, is an artifact during cloning derived from caldecrin gene". J. Biochem. 123 (3): 546–54.
doi:
10.1093/oxfordjournals.jbchem.a021971.
PMID9538241.
Derikx MH, Szmola R, te Morsche RH, et al. (2009). "Tropical calcific pancreatitis and its association with CTRC and SPINK1 (p.N34S) variants". Eur J Gastroenterol Hepatol. 21 (8): 889–94.
doi:
10.1097/MEG.0b013e32832183cf.
PMID19404200.
S2CID22812634.