Histone-lysine N-methyltransferase EZH1 is an
enzyme that in humans is encoded by the EZH1gene.[5][6]
Function
In mice, EZH1 and
EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair.[7] EZH1 also complements EZH2 in maintaining stem cell identity and executing pluripotency.[8]
Rommens JM, Durocher F, McArthur J, et al. (1996). "Generation of a transcription map at the HSD17B locus centromeric to BRCA1 at 17q21". Genomics. 28 (3): 530–42.
doi:
10.1006/geno.1995.1185.
PMID7490091.
Osborne-Lawrence S, Welcsh PL, Spillman M, et al. (1995). "Direct selection of expressed sequences within a 1-Mb region flanking BRCA1 on human chromosome 17q21". Genomics. 25 (1): 248–55.
doi:
10.1016/0888-7543(95)80132-6.
PMID7774925.
Ogawa M, Hiraoka Y, Taniguchi K, Aiso S (1998). "Cloning and expression of a human/mouse Polycomb group gene, ENX-2/Enx-2". Biochim. Biophys. Acta. 1395 (2): 151–8.
doi:
10.1016/s0167-4781(97)00156-5.
PMID9473645.
Histone-lysine N-methyltransferase EZH1 is an
enzyme that in humans is encoded by the EZH1gene.[5][6]
Function
In mice, EZH1 and
EZH2 cogovern histone H3K27 trimethylation and are essential for hair follicle homeostasis and wound repair.[7] EZH1 also complements EZH2 in maintaining stem cell identity and executing pluripotency.[8]
Rommens JM, Durocher F, McArthur J, et al. (1996). "Generation of a transcription map at the HSD17B locus centromeric to BRCA1 at 17q21". Genomics. 28 (3): 530–42.
doi:
10.1006/geno.1995.1185.
PMID7490091.
Osborne-Lawrence S, Welcsh PL, Spillman M, et al. (1995). "Direct selection of expressed sequences within a 1-Mb region flanking BRCA1 on human chromosome 17q21". Genomics. 25 (1): 248–55.
doi:
10.1016/0888-7543(95)80132-6.
PMID7774925.
Ogawa M, Hiraoka Y, Taniguchi K, Aiso S (1998). "Cloning and expression of a human/mouse Polycomb group gene, ENX-2/Enx-2". Biochim. Biophys. Acta. 1395 (2): 151–8.
doi:
10.1016/s0167-4781(97)00156-5.
PMID9473645.