EPN may refer to: End Polio Now, the Polio eradication campaign of Rotary International and the World Health Organization

• Economic Prosperity Network, a global alliance initiative of the Trump administration
• EPN (insecticide)
• Effective perceived noise, a measure of aircraft noise
• Electronic Payments Network, an electronic clearing house
• Enrique Peña Nieto, President of Mexico 2012–2018
• Enterprise private network, an intranet in a large organisation
• Entomopathogenic nematode, thread worm that kills insects
• Epsin, a membrane protein
• Esplanade MRT station, Singapore (MRT station abbreviation)
• EUREF Permanent Network, a European GPS network
• National Polytechnic School (Ecuador) (Spanish: Escuela Politécnica Nacional), a university in Quito

This disambiguation page lists articles associated with the title EPN.
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