| EGOT | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | EGOT, EGO, NCRNA00190, eosinophil granule ontogeny transcript (non-protein coding), eosinophil granule ontogeny transcript | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 611662; GeneCards: EGOT; OMA: EGOT - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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EGOT, also known as Eosinophil Granule Ontogeny (EGO)† Transcript ( non-protein coding), [3] is a human gene at 3p26.1 that produces a long noncoding RNA molecule. EGOT is nested within an intron of the inositol triphosphate receptor type 1 ( ITPR1) gene. The EGOT transcript is expressed during eosinophil development and is possibly involved in regulating eosinophil granule protein expression. [3] Comparison of EGO-B, the spliced isoform, suggests EGOT may be conserved across placental mammals. [4]
†Originally published as EGO but renamed as EGOT because 'EGO' is a real word and is therefore problematic when searching the scientific literature. [5]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000235947 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b Wagner LA, Christensen CJ, Dunn DM, et al. (June 2007). "EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression". Blood. 109 (12): 5191–5198. doi: 10.1182/blood-2006-06-027987. PMC 1890841. PMID 17351112.
- ^ Rose D, Stadler PF (October 2011). "Molecular evolution of the non-coding eosinophil granule ontogeny transcript". Front Genet. 2: 69. doi: 10.3389/fgene.2011.00069. PMC 3268622. PMID 22303364.
- ^ Wright, MW (Apr 9, 2014). "A short guide to long non-coding RNA gene nomenclature". Human Genomics. 8 (1): 7. doi: 10.1186/1479-7364-8-7. PMC 4021045. PMID 24716852.
| EGOT | |||||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | EGOT, EGO, NCRNA00190, eosinophil granule ontogeny transcript (non-protein coding), eosinophil granule ontogeny transcript | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 611662; GeneCards: EGOT; OMA: EGOT - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
EGOT, also known as Eosinophil Granule Ontogeny (EGO)† Transcript ( non-protein coding), [3] is a human gene at 3p26.1 that produces a long noncoding RNA molecule. EGOT is nested within an intron of the inositol triphosphate receptor type 1 ( ITPR1) gene. The EGOT transcript is expressed during eosinophil development and is possibly involved in regulating eosinophil granule protein expression. [3] Comparison of EGO-B, the spliced isoform, suggests EGOT may be conserved across placental mammals. [4]
†Originally published as EGO but renamed as EGOT because 'EGO' is a real word and is therefore problematic when searching the scientific literature. [5]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000235947 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ a b Wagner LA, Christensen CJ, Dunn DM, et al. (June 2007). "EGO, a novel, noncoding RNA gene, regulates eosinophil granule protein transcript expression". Blood. 109 (12): 5191–5198. doi: 10.1182/blood-2006-06-027987. PMC 1890841. PMID 17351112.
- ^ Rose D, Stadler PF (October 2011). "Molecular evolution of the non-coding eosinophil granule ontogeny transcript". Front Genet. 2: 69. doi: 10.3389/fgene.2011.00069. PMC 3268622. PMID 22303364.
- ^ Wright, MW (Apr 9, 2014). "A short guide to long non-coding RNA gene nomenclature". Human Genomics. 8 (1): 7. doi: 10.1186/1479-7364-8-7. PMC 4021045. PMID 24716852.