Transcription factor COE1 is a
protein that in humans is encoded by the EBF1gene.
EBF1 stands for Early B-Cell Factor 1.[5][6][7]
EBF1 controls the expression of key proteins required for B cell differentiation, signal transduction and function.[8][9] The crucial role of this factor is shown in the regulation of expression of SLAM family co-receptors in B-cells.[10] In addition, EBF1 is also noted for its role in
chondrogenic differentiation in limb bud
mesenchymalprogenitor cells.[11]
^Milatovich A, Qiu RG, Grosschedl R, Francke U (Jul 1994). "Gene for a tissue-specific transcriptional activator (EBF or Olf-1), expressed in early B lymphocytes, adipocytes, and olfactory neurons, is located on human chromosome 5, band q34, and proximal mouse chromosome 11". Mamm. Genome. 5 (4): 211–5.
doi:
10.1007/BF00360547.
PMID8012110.
S2CID19839522.
^Hagman J, Ramírez J, Lukin K (2012-01-01). "B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1". Epigenetic Regulation of Lymphocyte Development. Current Topics in Microbiology and Immunology. Vol. 356. pp. 17–38.
doi:
10.1007/82_2011_139.
ISBN978-3-642-24102-4.
ISSN0070-217X.
PMC3925327.
PMID21735360.
^Schwartz AM, Putlyaeva LV, Covich M, Klepikova AV, Akulich KA, Vorontsov IE, Korneev KV, Dmitriev SE, Polanovsky OL (2016-10-01). "Early B-cell factor 1 (EBF1) is critical for transcriptional control of SLAMF1 gene in human B cells". Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1859 (10): 1259–1268.
doi:
10.1016/j.bbagrm.2016.07.004.
PMID27424222.
Transcription factor COE1 is a
protein that in humans is encoded by the EBF1gene.
EBF1 stands for Early B-Cell Factor 1.[5][6][7]
EBF1 controls the expression of key proteins required for B cell differentiation, signal transduction and function.[8][9] The crucial role of this factor is shown in the regulation of expression of SLAM family co-receptors in B-cells.[10] In addition, EBF1 is also noted for its role in
chondrogenic differentiation in limb bud
mesenchymalprogenitor cells.[11]
^Milatovich A, Qiu RG, Grosschedl R, Francke U (Jul 1994). "Gene for a tissue-specific transcriptional activator (EBF or Olf-1), expressed in early B lymphocytes, adipocytes, and olfactory neurons, is located on human chromosome 5, band q34, and proximal mouse chromosome 11". Mamm. Genome. 5 (4): 211–5.
doi:
10.1007/BF00360547.
PMID8012110.
S2CID19839522.
^Hagman J, Ramírez J, Lukin K (2012-01-01). "B Lymphocyte Lineage Specification, Commitment and Epigenetic Control of Transcription by Early B Cell Factor 1". Epigenetic Regulation of Lymphocyte Development. Current Topics in Microbiology and Immunology. Vol. 356. pp. 17–38.
doi:
10.1007/82_2011_139.
ISBN978-3-642-24102-4.
ISSN0070-217X.
PMC3925327.
PMID21735360.
^Schwartz AM, Putlyaeva LV, Covich M, Klepikova AV, Akulich KA, Vorontsov IE, Korneev KV, Dmitriev SE, Polanovsky OL (2016-10-01). "Early B-cell factor 1 (EBF1) is critical for transcriptional control of SLAMF1 gene in human B cells". Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms. 1859 (10): 1259–1268.
doi:
10.1016/j.bbagrm.2016.07.004.
PMID27424222.