In pharmacology and medicine, vectorization of drugs refers to ( intracellular) targeting with plastic, noble metal or silicon nanoparticles or liposomes to which pharmacologically active substances are reversibly bound or attached by adsorption. [1] [2]
CNRS researchers have devised a way to overcome the problem of multidrug resistance using polyalkyl cyanoacrylate (PACA) nanoparticles as " vectors". [3]
As a developing concept, drug nanocarriers are expected to play a major role in delivering multiple drugs to tumor tissues by overcoming semi-permeable membranes and biological barriers such as the blood–brain barrier. [4]
References
- ^ Couvreur P. (2001). "Drug vectorization or how to modulate tissular and cellular distribution of biologically active compounds". Ann Pharm Fr. 59 (4): 232–8. PMID 11468577.
- ^ Secret, Emilie; Smith, Kevin; Dubljevic, Valentina; Moore, Eli; Macardle, Peter; et al. (2012-11-30). "Antibody-Functionalized Porous Silicon Nanoparticles for Vectorization of Hydrophobic Drugs". Advanced Healthcare Materials. 2 (5). Wiley: 718–727. doi: 10.1002/adhm.201200335. ISSN 2192-2640. PMID 23203914. S2CID 879226.
- ^ "CNRSinfo - en380a6". Archived from the original on 2015-07-19. Retrieved 2016-01-28.
- ^ Su, Chia-Wei; Chiang, Chih-Sheng; Li, Wei-Ming; Hu, Shang-Hsiu; Chen, San-Yuan (2014). "Multifunctional nanocarriers for simultaneous encapsulation of hydrophobic and hydrophilic drugs in cancer treatment". Nanomedicine (Lond.). 9 (10): 1499–515. doi: 10.2217/nnm.14.97. PMID 25253498.
See also
- Vector (molecular biology)
- Cancer treatment
- Nanomedicine
- Nanobiotechnology
- Paul Ehrlich#Magic bullet
- Gold nanobeacons
 | This pharmacy-related article is a stub. You can help Wikipedia by expanding it. |
In pharmacology and medicine, vectorization of drugs refers to ( intracellular) targeting with plastic, noble metal or silicon nanoparticles or liposomes to which pharmacologically active substances are reversibly bound or attached by adsorption. [1] [2]
CNRS researchers have devised a way to overcome the problem of multidrug resistance using polyalkyl cyanoacrylate (PACA) nanoparticles as " vectors". [3]
As a developing concept, drug nanocarriers are expected to play a major role in delivering multiple drugs to tumor tissues by overcoming semi-permeable membranes and biological barriers such as the blood–brain barrier. [4]
References
- ^ Couvreur P. (2001). "Drug vectorization or how to modulate tissular and cellular distribution of biologically active compounds". Ann Pharm Fr. 59 (4): 232–8. PMID 11468577.
- ^ Secret, Emilie; Smith, Kevin; Dubljevic, Valentina; Moore, Eli; Macardle, Peter; et al. (2012-11-30). "Antibody-Functionalized Porous Silicon Nanoparticles for Vectorization of Hydrophobic Drugs". Advanced Healthcare Materials. 2 (5). Wiley: 718–727. doi: 10.1002/adhm.201200335. ISSN 2192-2640. PMID 23203914. S2CID 879226.
- ^ "CNRSinfo - en380a6". Archived from the original on 2015-07-19. Retrieved 2016-01-28.
- ^ Su, Chia-Wei; Chiang, Chih-Sheng; Li, Wei-Ming; Hu, Shang-Hsiu; Chen, San-Yuan (2014). "Multifunctional nanocarriers for simultaneous encapsulation of hydrophobic and hydrophilic drugs in cancer treatment". Nanomedicine (Lond.). 9 (10): 1499–515. doi: 10.2217/nnm.14.97. PMID 25253498.
See also
- Vector (molecular biology)
- Cancer treatment
- Nanomedicine
- Nanobiotechnology
- Paul Ehrlich#Magic bullet
- Gold nanobeacons
|
| This pharmacy-related article is a stub. You can help Wikipedia by expanding it. |