From Wikipedia, the free encyclopedia
  • Comment: This needs to be written by summarising what reliable published sources have said. Which source provides eg. that "DVS was also a fun a play on the word "Devious" suggested by Scott's daughter" (which, incidentally, is also completely inappropriate for an encyclopaedia article)? Or the information in the 'First Commercial installation' section?
    Press releases and other primary sources, routine business reporting, etc. does not establish notability per WP:GNG / WP:ORGCRIT. We need to see at least three reliable and fully independent secondary sources with significant coverage directly of the subject. DoubleGrazing ( talk) 06:51, 16 October 2023 (UTC)

For the next reviewer

Please read the "Talk" page first

DVS Sciences Offices in Markham Ontario Canada (2014)
DVS Sciences Inc.
Company type Private
Founded2004; 20 years ago (2004)
Headquarters,
Key people
Scott D. Tanner
(President)

Dmitry Bandura
(CTO / Physicist)

Vladimir Baranov
(Chief Scientist)

Olga Ornatsky
(Chief Biologist)
Number of employees
57 (February 2014)
Website web.archive.org/web/20140208060238/http://www.dvssciences.com/

DVS Sciences Inc. (now Defunct) was a Canadian company engaged in the design, manufacture and sale of biological research equipment [1] ( Mass cytometry) before being acquired by Fluidigm in 2014. [2]

Company Name and Founders

DVS Sciences was originally founded by 'Dmitry Bandura, Vladimir Baranov and Scott Tanner [3] to provide consulting services as a condition of their spin-out to the University of Toronto from their previous employer. The first initial of each name was used for the company name DVS Sciences. (DVS was also a fun a play on the word "Devious" suggested by Scott's daughter). Olga Ornatsky was also a principal in the company, but could not be named in the original founding due to the terms of the consulting contract. [4] DVS Sciences formally became an instruments-and-reagents company in March 2006 when selected as the Commercialization Partner by the funders of the university research project. [4]

History

The concept for using atomic mass spectrometry as a reader for element-tagged biomarkers was first conceived and patented [5] by Scott D. Tanner and colleagues in 2000 while working for MDS SCIEX. The patent application that first described the technology of the CyTOF instrument was (finally) submitted in 2005. [6] SCIEX felt unable to devote the resources to develop and commercialize the idea, but agreed to license the patent to DVS Sciences. Initial funding for the development of the technology of mass cytometry was provided by Genome Canada through the Ontario Genomics Institute, with additional support from the Ministry of Research, Innovation and Science and the Ontario Institute for Cancer Research. [4] [7]

With funding from Genome Canada and the faculties of Engineering, Medicine and Arts & Science at the University of Toronto, Scott, Dmitry, Vladimir and Olga found a new physical home in a purpose-built laboratory in the basement of the chemistry building at UofT. [8]

CyTOF Breadboard Prototype
Jan 25 2006
CyTOF Zero Phase Prototype
May 09 2007
Early DVS Sciences Team in the basement at the University of Toronto Sept 29 2005

Olga Ornatsky, Amy Dambrowitz
Alexei Antonov, Vladimir Baranov,
Sergey Vorobiev, Scott D. Tanner,
and Dmitry Bandura

The CyTOF instrument was officially launched at the Great Lakes International Imaging and Flow Cytometry Association meeting in Pittsburgh in late 2009. [9] [10] A larger launch took place at the International Society for the Advancement of Cytometry in May 2010. [11] By the end of 2010, DVS Sciences had installed four CyTOF instruments (OICR, NIH, Stanford University, Academica Sinica Taiwan) and closed a Series A investment [12] from a syndicate led by 5am Ventures and including Pfizer Ventures, Mohr Davidow and Roche Ventures. The investment allowed the establishment of an independent home for DVS Sciences in Markham Ontario, the opening of a corporate head office in Sunnyvale California, and the assembly of a global sales and marketing team. [13]

The CyTOF instrument, and DVS Sciences, came to prominence with the 2011 publication of a seminal paper by the Nolan group at Stanford University. [14] Imaging Mass Cytometry was introduced in a 2014 seminal paper by the Bodenmiller ( University of Zurich) and Gunther ( ETH Zurich) groups. [15]

Fluidigm Corp (now Standard BioTools) acquired DVS Sciences in 2014. [16]

First Commercial installation

The worlds first CyTOF was sold to the University Health Network (John Dick) through funding provided by the Ontario Institute for Cancer Research (OICR). This instrument was soon after installed at the University of Toronto laboratory where it remained and was operated on behalf of the OICR until 2013, when it was donated to the Hospital for Sick Children (Toronto).

Products

DVS Sciences designed and manufactured the CyTOF instrument along with MaxPar reagents. Prior to the Fluidigm acquisition, DVS Sciences produced two versions of the CyTOF instrument, CyTOF [17] (Code-Named Beta and later as C5) and CyTOF2 [18] [19](Code-Named Omega and later as C7). They also manufactured an AutoSampler (AS-5). [20]

Awards

  • 2011 - Top 10 Innovations of 2011 (The Scientist) [21]
  • 2011 - York Technology Alliance Momentum Company of the Year. [22]
  • 2014 - Life Sciences Ontario Company of the Year. [23] [24]

External links

References

  1. ^ "Company Profile (2014)". PitchBook.com. 2014.
  2. ^ "Fluidigm Corporation completed the acquisition of DVS Sciences Inc" (Press release). marketscreener.com. 12 February 2014.
  3. ^ "The Four Co-Founders of DVS Sciences". 2011.
  4. ^ a b c Scott D. Tanner (Summer 2023). Personal and Historical Recollections of the Early Years of Mass Cytometry, Scott D. Tanner, in Revealing Unchartered Biology with Single Intact Cells: ed.Wendy Fantl. Elsevier.
  5. ^ "US Patent 7,135,296". Google Patents. 2000-12-28. Retrieved 6 December 2022.
  6. ^ Vladimir I. Baranov; Dmitry R. Bandura; Scott D. Tanner (January 20, 2009). "US patent number 7,479,630, Method and Apparatus for Flow Cytometry Linked with Elemental Analysis". Google Patents.
  7. ^ "DVS Sciences Early Funding" (Press release). dvssciences.com. 2005. Archived from the original on 2009-06-20. Retrieved 2022-11-20.{{ cite press release}}: CS1 maint: bot: original URL status unknown ( link)
  8. ^ "Early history" (PDF). StemSpecs.ca. 2005. Archived from the original on 2009-07-04. Retrieved 2022-12-19.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  9. ^ "CyTOF Launch". Bio Technology Focus. December 2009.
  10. ^ "DVS Sciences Unveils First-in-Class Mass Cytometer for Use in Understanding and Diagnosing Disease, Technology Networks genomics Research". Technology Networks. November 26, 2009.
  11. ^ "University of Toronto Spinout Rolls Out New Biomarker System with Eye on Bead Array Market". GenomeWeb. May 21, 2010.
  12. ^ "DVS Sciences Raises $14.6M Series A Funding for Multiparameter Single-Cell Mass Cytometry Platform". GenengNews. Genetic Engineering and Biotechnology News. July 14, 2011.
  13. ^ "Small Canadian biotech firm lands financing". The Globe and Mail. July 14, 2011. Archived from the original on July 15, 2011. Retrieved September 16, 2023.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  14. ^ Sean C. Bendall; Erin F. Simonds; Peng Qiu; El-ad D. Amir; Peter O. Krutzik; Rachel Finck; Robert V. Bruggner; Rachel Melamed; Angelica Trejo; Olga I. Ornatsky; Robert S. Balderas; Sylvia K. Plevritis; Karen Sachs; Dana Pe’er; Scott D. Tanner; Garry P. Nolan (2011). "Single-cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum, Science, 332, 687-696". Science. 332 (6030): 687–696. doi: 10.1126/science.1198704. PMC  3273988. PMID  21551058.
  15. ^ Charlotte Giesen; Hao A O Wang; Denis Schapiro; Nevena Zivanovic; Andrea Jacobs; Bodo Hattendorf; Peter J Schüffler; Daniel Grolimund; Joachim M Buhmann; Simone Brandt; Zsuzsanna Varga; Peter J Wild; Detlef Günther; Bernd Bodenmiller (2014). "Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry, Nature Methods 11 417-422". Nature Methods. 11 (4): 417–422. doi: 10.1038/nmeth.2869. PMID  24584193.
  16. ^ "Fluidigm Completes Acquisition of DVS Sciences". facit.ca. February 13, 2014.
  17. ^ "CyTOF® Instrument". 2011. Archived from the original on 2012-07-11. Retrieved 2022-12-18.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  18. ^ "New CyTOF® 2 Instrument". 2013. Archived from the original on 2014-02-13. Retrieved 2022-12-18.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  19. ^ "Cytof® 2 Pres Release". Fluidigm.com. May 4, 2013.
  20. ^ "AS-5 - CyTOF2 User-Guide". Manualzz.com. p. 12.
  21. ^ "Top Ten Innovations 2011". The Scientist. Jan 1, 2011. Archived from the original on January 8, 2012. Retrieved January 5, 2023.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  22. ^ "York Technology Alliance Momentum Company of the Year". PRWweb.com. June 8, 2011.
  23. ^ "Life Sciences Ontario Company of the Year". LifeSciencesOntario.ca. 2014.
  24. ^ "LSO Gala 2014 - Company of the Year - DVS Sciences". YouTube. 2014.

Category:Technology companies of Canada Category:Laboratory equipment manufacturers

From Wikipedia, the free encyclopedia
  • Comment: This needs to be written by summarising what reliable published sources have said. Which source provides eg. that "DVS was also a fun a play on the word "Devious" suggested by Scott's daughter" (which, incidentally, is also completely inappropriate for an encyclopaedia article)? Or the information in the 'First Commercial installation' section?
    Press releases and other primary sources, routine business reporting, etc. does not establish notability per WP:GNG / WP:ORGCRIT. We need to see at least three reliable and fully independent secondary sources with significant coverage directly of the subject. DoubleGrazing ( talk) 06:51, 16 October 2023 (UTC)

For the next reviewer

Please read the "Talk" page first

DVS Sciences Offices in Markham Ontario Canada (2014)
DVS Sciences Inc.
Company type Private
Founded2004; 20 years ago (2004)
Headquarters,
Key people
Scott D. Tanner
(President)

Dmitry Bandura
(CTO / Physicist)

Vladimir Baranov
(Chief Scientist)

Olga Ornatsky
(Chief Biologist)
Number of employees
57 (February 2014)
Website web.archive.org/web/20140208060238/http://www.dvssciences.com/

DVS Sciences Inc. (now Defunct) was a Canadian company engaged in the design, manufacture and sale of biological research equipment [1] ( Mass cytometry) before being acquired by Fluidigm in 2014. [2]

Company Name and Founders

DVS Sciences was originally founded by 'Dmitry Bandura, Vladimir Baranov and Scott Tanner [3] to provide consulting services as a condition of their spin-out to the University of Toronto from their previous employer. The first initial of each name was used for the company name DVS Sciences. (DVS was also a fun a play on the word "Devious" suggested by Scott's daughter). Olga Ornatsky was also a principal in the company, but could not be named in the original founding due to the terms of the consulting contract. [4] DVS Sciences formally became an instruments-and-reagents company in March 2006 when selected as the Commercialization Partner by the funders of the university research project. [4]

History

The concept for using atomic mass spectrometry as a reader for element-tagged biomarkers was first conceived and patented [5] by Scott D. Tanner and colleagues in 2000 while working for MDS SCIEX. The patent application that first described the technology of the CyTOF instrument was (finally) submitted in 2005. [6] SCIEX felt unable to devote the resources to develop and commercialize the idea, but agreed to license the patent to DVS Sciences. Initial funding for the development of the technology of mass cytometry was provided by Genome Canada through the Ontario Genomics Institute, with additional support from the Ministry of Research, Innovation and Science and the Ontario Institute for Cancer Research. [4] [7]

With funding from Genome Canada and the faculties of Engineering, Medicine and Arts & Science at the University of Toronto, Scott, Dmitry, Vladimir and Olga found a new physical home in a purpose-built laboratory in the basement of the chemistry building at UofT. [8]

CyTOF Breadboard Prototype
Jan 25 2006
CyTOF Zero Phase Prototype
May 09 2007
Early DVS Sciences Team in the basement at the University of Toronto Sept 29 2005

Olga Ornatsky, Amy Dambrowitz
Alexei Antonov, Vladimir Baranov,
Sergey Vorobiev, Scott D. Tanner,
and Dmitry Bandura

The CyTOF instrument was officially launched at the Great Lakes International Imaging and Flow Cytometry Association meeting in Pittsburgh in late 2009. [9] [10] A larger launch took place at the International Society for the Advancement of Cytometry in May 2010. [11] By the end of 2010, DVS Sciences had installed four CyTOF instruments (OICR, NIH, Stanford University, Academica Sinica Taiwan) and closed a Series A investment [12] from a syndicate led by 5am Ventures and including Pfizer Ventures, Mohr Davidow and Roche Ventures. The investment allowed the establishment of an independent home for DVS Sciences in Markham Ontario, the opening of a corporate head office in Sunnyvale California, and the assembly of a global sales and marketing team. [13]

The CyTOF instrument, and DVS Sciences, came to prominence with the 2011 publication of a seminal paper by the Nolan group at Stanford University. [14] Imaging Mass Cytometry was introduced in a 2014 seminal paper by the Bodenmiller ( University of Zurich) and Gunther ( ETH Zurich) groups. [15]

Fluidigm Corp (now Standard BioTools) acquired DVS Sciences in 2014. [16]

First Commercial installation

The worlds first CyTOF was sold to the University Health Network (John Dick) through funding provided by the Ontario Institute for Cancer Research (OICR). This instrument was soon after installed at the University of Toronto laboratory where it remained and was operated on behalf of the OICR until 2013, when it was donated to the Hospital for Sick Children (Toronto).

Products

DVS Sciences designed and manufactured the CyTOF instrument along with MaxPar reagents. Prior to the Fluidigm acquisition, DVS Sciences produced two versions of the CyTOF instrument, CyTOF [17] (Code-Named Beta and later as C5) and CyTOF2 [18] [19](Code-Named Omega and later as C7). They also manufactured an AutoSampler (AS-5). [20]

Awards

  • 2011 - Top 10 Innovations of 2011 (The Scientist) [21]
  • 2011 - York Technology Alliance Momentum Company of the Year. [22]
  • 2014 - Life Sciences Ontario Company of the Year. [23] [24]

External links

References

  1. ^ "Company Profile (2014)". PitchBook.com. 2014.
  2. ^ "Fluidigm Corporation completed the acquisition of DVS Sciences Inc" (Press release). marketscreener.com. 12 February 2014.
  3. ^ "The Four Co-Founders of DVS Sciences". 2011.
  4. ^ a b c Scott D. Tanner (Summer 2023). Personal and Historical Recollections of the Early Years of Mass Cytometry, Scott D. Tanner, in Revealing Unchartered Biology with Single Intact Cells: ed.Wendy Fantl. Elsevier.
  5. ^ "US Patent 7,135,296". Google Patents. 2000-12-28. Retrieved 6 December 2022.
  6. ^ Vladimir I. Baranov; Dmitry R. Bandura; Scott D. Tanner (January 20, 2009). "US patent number 7,479,630, Method and Apparatus for Flow Cytometry Linked with Elemental Analysis". Google Patents.
  7. ^ "DVS Sciences Early Funding" (Press release). dvssciences.com. 2005. Archived from the original on 2009-06-20. Retrieved 2022-11-20.{{ cite press release}}: CS1 maint: bot: original URL status unknown ( link)
  8. ^ "Early history" (PDF). StemSpecs.ca. 2005. Archived from the original on 2009-07-04. Retrieved 2022-12-19.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  9. ^ "CyTOF Launch". Bio Technology Focus. December 2009.
  10. ^ "DVS Sciences Unveils First-in-Class Mass Cytometer for Use in Understanding and Diagnosing Disease, Technology Networks genomics Research". Technology Networks. November 26, 2009.
  11. ^ "University of Toronto Spinout Rolls Out New Biomarker System with Eye on Bead Array Market". GenomeWeb. May 21, 2010.
  12. ^ "DVS Sciences Raises $14.6M Series A Funding for Multiparameter Single-Cell Mass Cytometry Platform". GenengNews. Genetic Engineering and Biotechnology News. July 14, 2011.
  13. ^ "Small Canadian biotech firm lands financing". The Globe and Mail. July 14, 2011. Archived from the original on July 15, 2011. Retrieved September 16, 2023.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  14. ^ Sean C. Bendall; Erin F. Simonds; Peng Qiu; El-ad D. Amir; Peter O. Krutzik; Rachel Finck; Robert V. Bruggner; Rachel Melamed; Angelica Trejo; Olga I. Ornatsky; Robert S. Balderas; Sylvia K. Plevritis; Karen Sachs; Dana Pe’er; Scott D. Tanner; Garry P. Nolan (2011). "Single-cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum, Science, 332, 687-696". Science. 332 (6030): 687–696. doi: 10.1126/science.1198704. PMC  3273988. PMID  21551058.
  15. ^ Charlotte Giesen; Hao A O Wang; Denis Schapiro; Nevena Zivanovic; Andrea Jacobs; Bodo Hattendorf; Peter J Schüffler; Daniel Grolimund; Joachim M Buhmann; Simone Brandt; Zsuzsanna Varga; Peter J Wild; Detlef Günther; Bernd Bodenmiller (2014). "Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry, Nature Methods 11 417-422". Nature Methods. 11 (4): 417–422. doi: 10.1038/nmeth.2869. PMID  24584193.
  16. ^ "Fluidigm Completes Acquisition of DVS Sciences". facit.ca. February 13, 2014.
  17. ^ "CyTOF® Instrument". 2011. Archived from the original on 2012-07-11. Retrieved 2022-12-18.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  18. ^ "New CyTOF® 2 Instrument". 2013. Archived from the original on 2014-02-13. Retrieved 2022-12-18.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  19. ^ "Cytof® 2 Pres Release". Fluidigm.com. May 4, 2013.
  20. ^ "AS-5 - CyTOF2 User-Guide". Manualzz.com. p. 12.
  21. ^ "Top Ten Innovations 2011". The Scientist. Jan 1, 2011. Archived from the original on January 8, 2012. Retrieved January 5, 2023.{{ cite web}}: CS1 maint: bot: original URL status unknown ( link)
  22. ^ "York Technology Alliance Momentum Company of the Year". PRWweb.com. June 8, 2011.
  23. ^ "Life Sciences Ontario Company of the Year". LifeSciencesOntario.ca. 2014.
  24. ^ "LSO Gala 2014 - Company of the Year - DVS Sciences". YouTube. 2014.

Category:Technology companies of Canada Category:Laboratory equipment manufacturers


Videos

Youtube | Vimeo | Bing

Websites

Google | Yahoo | Bing

Encyclopedia

Google | Yahoo | Bing

Facebook