From Wikipedia, the free encyclopedia
Alexander Silberman Institute of Life Sciences
TypeResearch Institute
Established1925
Parent institution
The Hebrew University of Jerusalem
ChairpersonProf. Guy Bloch
Academic staff
75
Students900
Undergraduates600
Location
Jerusalem
,
Israel
LanguageHebrew & English
Website https://www.bio.huji.ac.il/en

The Alexander Silberman Institute of Life Sciences (AS-ILS) at the Hebrew University of Jerusalem is the oldest life sciences research institute in Israel. It is part of the Faculty of Sciences, and is located in the Edmond J. Safra Campus ( Givat Ram) in Jerusalem.

History

The origins of the institute date back to 1925, the year that the Hebrew University was founded, [1] when the Department of Botany was formed as part of a research unit called "The Institute for Studying the Natural History of the Land of Israel". Among the founding researchers were Profs. Otto Warburg, [2] Alexander Eig, [3] Michael Zohary [4] and Naomi Feinbrun-Dothan. [5] During the first years of the department, several large-scale projects that continue to this day have been started off, including the establishment of the Herbarium Collection, [6] today part of Israel's Natural History Collections, [7] and the establishment of the National Botanic Garden of Israel at Mount Scopus, which was the first of its kind in the Middle East.

In 1928, Prof. Simon Bodenheimer joined the nascent institute and established the Department of Zoology, leading the institute to probe into new scientific fields. [8]

Research activities at both departments (and at the Hebrew University in general) were diminished in 1948 during the War of Independence, and were brought to a complete stop following the Hadassah medical convoy massacre. Activity in both departments was renewed after the war, in April 1949. [1]

Notable achievements

Throughout the years AS-ILS members have conducted basic research as well as applied science in the fields of biomedicine, biotechnology and agriculture at multiple levels of organization, from molecular mechanism in cells, through processes within the whole organism, and to studies at the population level. AS-ILS members have been associated with several discoveries:

Study Programs

The institute offers a number of undergraduate programs, including a single major program, joint dual major programs, supplementary units, and a number of excellence programs. [39] [40]

References

  1. ^ a b "The Hebrew University of Jerusalem". www.jewishvirtuallibrary.org.
  2. ^ "Otto Warburg (botanist)". JSTOR Global Plants.
  3. ^ "Alexander Eig". JSTOR Global Plants.
  4. ^ "Michael Zohary". JSTOR Global Plants.
  5. ^ "Naomi Feinbrun-Dothan". Jewish Women's Archive.
  6. ^ "Something went wrong..." en-nnhc.huji.ac.il.
  7. ^ "The National Natural History Collections". en-nnhc.huji.ac.il.
  8. ^ Harpaz, I. (1984). "Frederick Simon Bodenheimer (1897–1959): Idealist, Scholar, Scientist". Annual Review of Entomology. 29: 1–24. doi: 10.1146/annurev.en.29.010184.000245. S2CID  86230193.
  9. ^ Eig, Alexander (1926). A contribution to the knowledge of the flora of Palestine (1st ed.). The Zionist organisation and the Hebrew Univ, Tel-Aviv.
  10. ^ GOLDSCHMIDT, ELISABETH; RONEN, AMIRAM; RONEN, ILANA (1960). "Changing marriage systems in the Jewish communities of Israel*". Annals of Human Genetics. 24 (3): 191–204. doi: 10.1111/j.1469-1809.1960.tb01732.x. ISSN  0003-4800. PMID  13850739.
  11. ^ Goldschmidt, E.; Cohen, T. (1964-01-01). "Inter-ethnic Mixture among the Communities of Israel". Cold Spring Harbor Symposia on Quantitative Biology. 29: 115–120. doi: 10.1101/sqb.1964.029.01.016. ISSN  0091-7451. PMID  14278459.
  12. ^ Horowitz, A.; Cohen, T.; Goldschmidt, E.; Levene, C. (1966). "Thalassaemia Types among Kurdish Jews in Israel". British Journal of Haematology. 12 (5): 555–568. doi: 10.1111/j.1365-2141.1966.tb00138.x. ISSN  0007-1048. PMID  5915052.
  13. ^ Zohary, Michael, ed. (1981). Flora Palaestina. Text: 1. Equisetaceae to moringaceae / by Michael Zohary (2. print ed.). Jerusalem: Israel Acad. of Sciences and Human. ISBN  978-965-208-001-1.
  14. ^ Levitzki, Alexander; Koshland, D. E. (1969). "Negative Cooperativity in Regulatory Enzymes". Proceedings of the National Academy of Sciences. 62 (4): 1121–1128. Bibcode: 1969PNAS...62.1121L. doi: 10.1073/pnas.62.4.1121. ISSN  0027-8424. PMC  223623. PMID  5256410.
  15. ^ Cassel, Dan; Selinger, Zvi (August 1977). "Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site". Proceedings of the National Academy of Sciences. 74 (8): 3307–3311. Bibcode: 1977PNAS...74.3307C. doi: 10.1073/pnas.74.8.3307. ISSN  0027-8424. PMC  431542. PMID  198781.
  16. ^ Huez, G.; Marbaix, G.; Burny, A.; Hubert, E.; Leclercq, M.; Cleuter, Y.; Chantrenne, H.; Soreq, H.; Littauer, U. Z. (March 1977). "Degradation of deadenylated rabbit α-globin mRNA in Xenopus oocytes is associated with its translation". Nature. 266 (5601): 473–474. Bibcode: 1977Natur.266..473H. doi: 10.1038/266473a0. ISSN  0028-0836. PMID  558522.
  17. ^ Atlas, Daphne; Levitzki, Alexander (1978). "Tentative identification of β-adrenoreceptor subunits". Nature. 272 (5651): 370–371. Bibcode: 1978Natur.272..370A. doi: 10.1038/272370a0. ISSN  0028-0836. PMID  204872.
  18. ^ Cassel, D; Selinger, Z (September 1978). "Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP". Proceedings of the National Academy of Sciences. 75 (9): 4155–4159. Bibcode: 1978PNAS...75.4155C. doi: 10.1073/pnas.75.9.4155. ISSN  0027-8424. PMC  336070. PMID  212737.
  19. ^ Zohary, Daniel; Hopf, Maria; Weiss, Ehud (2012). Domestication of plants in the Old World: the origin and spread of domesticated plants in Southwest Asia, Europe, and the Mediterranean Basin (Fourth ed.). Oxford: Oxford University Press. ISBN  978-0-19-954906-1.
  20. ^ Goldberg, E B; Arbel, T; Chen, J; Karpel, R; Mackie, G A; Schuldiner, S; Padan, E (May 1987). "Characterization of a Na+/H+ antiporter gene of Escherichia coli". Proceedings of the National Academy of Sciences. 84 (9): 2615–2619. doi: 10.1073/pnas.84.9.2615. ISSN  0027-8424. PMC  304708. PMID  3033655.
  21. ^ Yaish, Pnina; Gazit, Aviv; Gilon, Chaim; Levitzki, Alexander (1988-11-11). "Blocking of EGF-Dependent Cell Proliferation by EGF Receptor Kinase Inhibitors". Science. 242 (4880): 933–935. Bibcode: 1988Sci...242..933Y. doi: 10.1126/science.3263702. ISSN  0036-8075. PMID  3263702.
  22. ^ Kassir, Yona; Granot, David; Simchen, Giora (March 1988). "IME1, a positive regulator gene of meiosis in S. cerevisiae". Cell. 52 (6): 853–862. doi: 10.1016/0092-8674(88)90427-8. PMID  3280136.
  23. ^ Kerem, Bat-Sheva; Rommens, Johanna M.; Buchanan, Janet A.; Markiewicz, Danuta; Cox, Tara K.; Chakravarti, Aravinda; Buchwald, Manuel; Tsui, Lap-Chee (1989-09-08). "Identification of the Cystic Fibrosis Gene: Genetic Analysis". Science. 245 (4922): 1073–1080. Bibcode: 1989Sci...245.1073K. doi: 10.1126/science.2570460. ISSN  0036-8075. PMID  2570460.
  24. ^ Zenvirth, D.; Arbel, T.; Sherman, A.; Goldway, M.; Klein, S.; Simchen, G. (September 1992). "Multiple sites for double-strand breaks in whole meiotic chromosomes of Saccharomyces cerevisiae". The EMBO Journal. 11 (9): 3441–3447. doi: 10.1002/j.1460-2075.1992.tb05423.x. PMC  556879. PMID  1324174.
  25. ^ Kaufer, Daniela; Friedman, Alon; Seidman, Shlomo; Soreq, Hermona (1998-05-28). "Acute stress facilitates long-lasting changes in cholinergic gene expression". Nature. 393 (6683): 373–377. Bibcode: 1998Natur.393..373K. doi: 10.1038/30741. ISSN  0028-0836. PMID  9620801.
  26. ^ Eiges, Rachel; Schuldiner, Maya; Drukker, Micha; Yanuka, Ofra; Itskovitz-Eldor, Joseph; Benvenisty, Nissim (April 2001). "Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells". Current Biology. 11 (7): 514–518. Bibcode: 2001CBio...11..514E. doi: 10.1016/S0960-9822(01)00144-0. PMID  11413002.
  27. ^ Avior, Yishai; Sagi, Ido; Benvenisty, Nissim (March 2016). "Pluripotent stem cells in disease modelling and drug discovery". Nature Reviews Molecular Cell Biology. 17 (3): 170–182. doi: 10.1038/nrm.2015.27. ISSN  1471-0072. PMID  26818440.
  28. ^ Drukker, Micha; Katz, Gil; Urbach, Achia; Schuldiner, Maya; Markel, Gal; Itskovitz-Eldor, Joseph; Reubinoff, Benjamin; Mandelboim, Ofer; Benvenisty, Nissim (2002-07-23). "Characterization of the expression of MHC proteins in human embryonic stem cells". Proceedings of the National Academy of Sciences. 99 (15): 9864–9869. Bibcode: 2002PNAS...99.9864D. doi: 10.1073/pnas.142298299. ISSN  0027-8424. PMC  125045. PMID  12114532.
  29. ^ Blum, Barak; Bar-Nur, Ori; Golan-Lev, Tamar; Benvenisty, Nissim (March 2009). "The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells". Nature Biotechnology. 27 (3): 281–287. doi: 10.1038/nbt.1527. ISSN  1087-0156. PMID  19252483.
  30. ^ Tal, Nir; Schuldiner, Shimon (2009-06-02). "A coordinated network of transporters with overlapping specificities provides a robust survival strategy". Proceedings of the National Academy of Sciences. 106 (22): 9051–9056. Bibcode: 2009PNAS..106.9051T. doi: 10.1073/pnas.0902400106. ISSN  0027-8424. PMC  2690002. PMID  19451626.
  31. ^ Bester, Assaf C.; Roniger, Maayan; Oren, Yifat S.; Im, Michael M.; Sarni, Dan; Chaoat, Malka; Bensimon, Aaron; Zamir, Gideon; Shewach, Donna S.; Kerem, Batsheva (April 2011). "Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development". Cell. 145 (3): 435–446. doi: 10.1016/j.cell.2011.03.044. PMC  3740329. PMID  21529715.
  32. ^ Nakamura, Kensuke; Inokuchi, Ryota; Doi, Kent; Fukuda, Tatsuma; Tokunaga, Kurato; Nakajima, Susumu; Noiri, Eisei; Yahagi, Naoki (2014). "Septic Ketoacidosis". Internal Medicine. 53 (10): 1071–1073. doi: 10.2169/internalmedicine.53.1791. ISSN  0918-2918. PMID  24827487.
  33. ^ Gokhman, David; Lavi, Eitan; Prüfer, Kay; Fraga, Mario F.; Riancho, José A.; Kelso, Janet; Pääbo, Svante; Meshorer, Eran; Carmel, Liran (2014-05-02). "Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan". Science. 344 (6183): 523–527. Bibcode: 2014Sci...344..523G. doi: 10.1126/science.1250368. ISSN  0036-8075. PMID  24786081.
  34. ^ Sagi, Ido; Chia, Gloryn; Golan-Lev, Tamar; Peretz, Mordecai; Weissbein, Uri; Sui, Lina; Sauer, Mark V.; Yanuka, Ofra; Egli, Dieter; Benvenisty, Nissim (2016-04-07). "Derivation and differentiation of haploid human embryonic stem cells". Nature. 532 (7597): 107–111. Bibcode: 2016Natur.532..107S. doi: 10.1038/nature17408. ISSN  0028-0836. PMID  26982723.
  35. ^ Yilmaz, Atilgan; Peretz, Mordecai; Aharony, Aviram; Sagi, Ido; Benvenisty, Nissim (May 2018). "Defining essential genes for human pluripotent stem cells by CRISPR–Cas9 screening in haploid cells". Nature Cell Biology. 20 (5): 610–619. doi: 10.1038/s41556-018-0088-1. ISSN  1465-7392. PMID  29662178.
  36. ^ Bar, Shiran; Vershkov, Dan; Keshet, Gal; Lezmi, Elyad; Meller, Naama; Yilmaz, Atilgan; Yanuka, Ofra; Nissim-Rafinia, Malka; Meshorer, Eran; Eldar-Geva, Talia; Benvenisty, Nissim (2021-11-18). "Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells". Nature Communications. 12 (1): 6718. Bibcode: 2021NatCo..12.6718B. doi: 10.1038/s41467-021-26949-7. ISSN  2041-1723. PMC  8602306. PMID  34795250.
  37. ^ Gokhman, David; Mishol, Nadav; de Manuel, Marc; de Juan, David; Shuqrun, Jonathan; Meshorer, Eran; Marques-Bonet, Tomas; Rak, Yoel; Carmel, Liran (September 2019). "Reconstructing Denisovan Anatomy Using DNA Methylation Maps". Cell. 179 (1): 180–192.e10. doi: 10.1016/j.cell.2019.08.035. PMID  31539495.
  38. ^ Winek, Katarzyna; Lobentanzer, Sebastian; Nadorp, Bettina; Dubnov, Serafima; Dames, Claudia; Jagdmann, Sandra; Moshitzky, Gilli; Hotter, Benjamin; Meisel, Christian; Greenberg, David S.; Shifman, Sagiv; Klein, Jochen; Shenhar-Tsarfaty, Shani; Meisel, Andreas; Soreq, Hermona (2020-12-22). "Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade". Proceedings of the National Academy of Sciences. 117 (51): 32606–32616. Bibcode: 2020PNAS..11732606W. doi: 10.1073/pnas.2013542117. ISSN  0027-8424. PMC  7768686. PMID  33288717.
  39. ^ "מידע על החוג". catalog.huji.ac.il.
  40. ^ "מידע על החוג". catalog.huji.ac.il.
From Wikipedia, the free encyclopedia
Alexander Silberman Institute of Life Sciences
TypeResearch Institute
Established1925
Parent institution
The Hebrew University of Jerusalem
ChairpersonProf. Guy Bloch
Academic staff
75
Students900
Undergraduates600
Location
Jerusalem
,
Israel
LanguageHebrew & English
Website https://www.bio.huji.ac.il/en

The Alexander Silberman Institute of Life Sciences (AS-ILS) at the Hebrew University of Jerusalem is the oldest life sciences research institute in Israel. It is part of the Faculty of Sciences, and is located in the Edmond J. Safra Campus ( Givat Ram) in Jerusalem.

History

The origins of the institute date back to 1925, the year that the Hebrew University was founded, [1] when the Department of Botany was formed as part of a research unit called "The Institute for Studying the Natural History of the Land of Israel". Among the founding researchers were Profs. Otto Warburg, [2] Alexander Eig, [3] Michael Zohary [4] and Naomi Feinbrun-Dothan. [5] During the first years of the department, several large-scale projects that continue to this day have been started off, including the establishment of the Herbarium Collection, [6] today part of Israel's Natural History Collections, [7] and the establishment of the National Botanic Garden of Israel at Mount Scopus, which was the first of its kind in the Middle East.

In 1928, Prof. Simon Bodenheimer joined the nascent institute and established the Department of Zoology, leading the institute to probe into new scientific fields. [8]

Research activities at both departments (and at the Hebrew University in general) were diminished in 1948 during the War of Independence, and were brought to a complete stop following the Hadassah medical convoy massacre. Activity in both departments was renewed after the war, in April 1949. [1]

Notable achievements

Throughout the years AS-ILS members have conducted basic research as well as applied science in the fields of biomedicine, biotechnology and agriculture at multiple levels of organization, from molecular mechanism in cells, through processes within the whole organism, and to studies at the population level. AS-ILS members have been associated with several discoveries:

Study Programs

The institute offers a number of undergraduate programs, including a single major program, joint dual major programs, supplementary units, and a number of excellence programs. [39] [40]

References

  1. ^ a b "The Hebrew University of Jerusalem". www.jewishvirtuallibrary.org.
  2. ^ "Otto Warburg (botanist)". JSTOR Global Plants.
  3. ^ "Alexander Eig". JSTOR Global Plants.
  4. ^ "Michael Zohary". JSTOR Global Plants.
  5. ^ "Naomi Feinbrun-Dothan". Jewish Women's Archive.
  6. ^ "Something went wrong..." en-nnhc.huji.ac.il.
  7. ^ "The National Natural History Collections". en-nnhc.huji.ac.il.
  8. ^ Harpaz, I. (1984). "Frederick Simon Bodenheimer (1897–1959): Idealist, Scholar, Scientist". Annual Review of Entomology. 29: 1–24. doi: 10.1146/annurev.en.29.010184.000245. S2CID  86230193.
  9. ^ Eig, Alexander (1926). A contribution to the knowledge of the flora of Palestine (1st ed.). The Zionist organisation and the Hebrew Univ, Tel-Aviv.
  10. ^ GOLDSCHMIDT, ELISABETH; RONEN, AMIRAM; RONEN, ILANA (1960). "Changing marriage systems in the Jewish communities of Israel*". Annals of Human Genetics. 24 (3): 191–204. doi: 10.1111/j.1469-1809.1960.tb01732.x. ISSN  0003-4800. PMID  13850739.
  11. ^ Goldschmidt, E.; Cohen, T. (1964-01-01). "Inter-ethnic Mixture among the Communities of Israel". Cold Spring Harbor Symposia on Quantitative Biology. 29: 115–120. doi: 10.1101/sqb.1964.029.01.016. ISSN  0091-7451. PMID  14278459.
  12. ^ Horowitz, A.; Cohen, T.; Goldschmidt, E.; Levene, C. (1966). "Thalassaemia Types among Kurdish Jews in Israel". British Journal of Haematology. 12 (5): 555–568. doi: 10.1111/j.1365-2141.1966.tb00138.x. ISSN  0007-1048. PMID  5915052.
  13. ^ Zohary, Michael, ed. (1981). Flora Palaestina. Text: 1. Equisetaceae to moringaceae / by Michael Zohary (2. print ed.). Jerusalem: Israel Acad. of Sciences and Human. ISBN  978-965-208-001-1.
  14. ^ Levitzki, Alexander; Koshland, D. E. (1969). "Negative Cooperativity in Regulatory Enzymes". Proceedings of the National Academy of Sciences. 62 (4): 1121–1128. Bibcode: 1969PNAS...62.1121L. doi: 10.1073/pnas.62.4.1121. ISSN  0027-8424. PMC  223623. PMID  5256410.
  15. ^ Cassel, Dan; Selinger, Zvi (August 1977). "Mechanism of adenylate cyclase activation by cholera toxin: Inhibition of GTP hydrolysis at the regulatory site". Proceedings of the National Academy of Sciences. 74 (8): 3307–3311. Bibcode: 1977PNAS...74.3307C. doi: 10.1073/pnas.74.8.3307. ISSN  0027-8424. PMC  431542. PMID  198781.
  16. ^ Huez, G.; Marbaix, G.; Burny, A.; Hubert, E.; Leclercq, M.; Cleuter, Y.; Chantrenne, H.; Soreq, H.; Littauer, U. Z. (March 1977). "Degradation of deadenylated rabbit α-globin mRNA in Xenopus oocytes is associated with its translation". Nature. 266 (5601): 473–474. Bibcode: 1977Natur.266..473H. doi: 10.1038/266473a0. ISSN  0028-0836. PMID  558522.
  17. ^ Atlas, Daphne; Levitzki, Alexander (1978). "Tentative identification of β-adrenoreceptor subunits". Nature. 272 (5651): 370–371. Bibcode: 1978Natur.272..370A. doi: 10.1038/272370a0. ISSN  0028-0836. PMID  204872.
  18. ^ Cassel, D; Selinger, Z (September 1978). "Mechanism of adenylate cyclase activation through the beta-adrenergic receptor: catecholamine-induced displacement of bound GDP by GTP". Proceedings of the National Academy of Sciences. 75 (9): 4155–4159. Bibcode: 1978PNAS...75.4155C. doi: 10.1073/pnas.75.9.4155. ISSN  0027-8424. PMC  336070. PMID  212737.
  19. ^ Zohary, Daniel; Hopf, Maria; Weiss, Ehud (2012). Domestication of plants in the Old World: the origin and spread of domesticated plants in Southwest Asia, Europe, and the Mediterranean Basin (Fourth ed.). Oxford: Oxford University Press. ISBN  978-0-19-954906-1.
  20. ^ Goldberg, E B; Arbel, T; Chen, J; Karpel, R; Mackie, G A; Schuldiner, S; Padan, E (May 1987). "Characterization of a Na+/H+ antiporter gene of Escherichia coli". Proceedings of the National Academy of Sciences. 84 (9): 2615–2619. doi: 10.1073/pnas.84.9.2615. ISSN  0027-8424. PMC  304708. PMID  3033655.
  21. ^ Yaish, Pnina; Gazit, Aviv; Gilon, Chaim; Levitzki, Alexander (1988-11-11). "Blocking of EGF-Dependent Cell Proliferation by EGF Receptor Kinase Inhibitors". Science. 242 (4880): 933–935. Bibcode: 1988Sci...242..933Y. doi: 10.1126/science.3263702. ISSN  0036-8075. PMID  3263702.
  22. ^ Kassir, Yona; Granot, David; Simchen, Giora (March 1988). "IME1, a positive regulator gene of meiosis in S. cerevisiae". Cell. 52 (6): 853–862. doi: 10.1016/0092-8674(88)90427-8. PMID  3280136.
  23. ^ Kerem, Bat-Sheva; Rommens, Johanna M.; Buchanan, Janet A.; Markiewicz, Danuta; Cox, Tara K.; Chakravarti, Aravinda; Buchwald, Manuel; Tsui, Lap-Chee (1989-09-08). "Identification of the Cystic Fibrosis Gene: Genetic Analysis". Science. 245 (4922): 1073–1080. Bibcode: 1989Sci...245.1073K. doi: 10.1126/science.2570460. ISSN  0036-8075. PMID  2570460.
  24. ^ Zenvirth, D.; Arbel, T.; Sherman, A.; Goldway, M.; Klein, S.; Simchen, G. (September 1992). "Multiple sites for double-strand breaks in whole meiotic chromosomes of Saccharomyces cerevisiae". The EMBO Journal. 11 (9): 3441–3447. doi: 10.1002/j.1460-2075.1992.tb05423.x. PMC  556879. PMID  1324174.
  25. ^ Kaufer, Daniela; Friedman, Alon; Seidman, Shlomo; Soreq, Hermona (1998-05-28). "Acute stress facilitates long-lasting changes in cholinergic gene expression". Nature. 393 (6683): 373–377. Bibcode: 1998Natur.393..373K. doi: 10.1038/30741. ISSN  0028-0836. PMID  9620801.
  26. ^ Eiges, Rachel; Schuldiner, Maya; Drukker, Micha; Yanuka, Ofra; Itskovitz-Eldor, Joseph; Benvenisty, Nissim (April 2001). "Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells". Current Biology. 11 (7): 514–518. Bibcode: 2001CBio...11..514E. doi: 10.1016/S0960-9822(01)00144-0. PMID  11413002.
  27. ^ Avior, Yishai; Sagi, Ido; Benvenisty, Nissim (March 2016). "Pluripotent stem cells in disease modelling and drug discovery". Nature Reviews Molecular Cell Biology. 17 (3): 170–182. doi: 10.1038/nrm.2015.27. ISSN  1471-0072. PMID  26818440.
  28. ^ Drukker, Micha; Katz, Gil; Urbach, Achia; Schuldiner, Maya; Markel, Gal; Itskovitz-Eldor, Joseph; Reubinoff, Benjamin; Mandelboim, Ofer; Benvenisty, Nissim (2002-07-23). "Characterization of the expression of MHC proteins in human embryonic stem cells". Proceedings of the National Academy of Sciences. 99 (15): 9864–9869. Bibcode: 2002PNAS...99.9864D. doi: 10.1073/pnas.142298299. ISSN  0027-8424. PMC  125045. PMID  12114532.
  29. ^ Blum, Barak; Bar-Nur, Ori; Golan-Lev, Tamar; Benvenisty, Nissim (March 2009). "The anti-apoptotic gene survivin contributes to teratoma formation by human embryonic stem cells". Nature Biotechnology. 27 (3): 281–287. doi: 10.1038/nbt.1527. ISSN  1087-0156. PMID  19252483.
  30. ^ Tal, Nir; Schuldiner, Shimon (2009-06-02). "A coordinated network of transporters with overlapping specificities provides a robust survival strategy". Proceedings of the National Academy of Sciences. 106 (22): 9051–9056. Bibcode: 2009PNAS..106.9051T. doi: 10.1073/pnas.0902400106. ISSN  0027-8424. PMC  2690002. PMID  19451626.
  31. ^ Bester, Assaf C.; Roniger, Maayan; Oren, Yifat S.; Im, Michael M.; Sarni, Dan; Chaoat, Malka; Bensimon, Aaron; Zamir, Gideon; Shewach, Donna S.; Kerem, Batsheva (April 2011). "Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development". Cell. 145 (3): 435–446. doi: 10.1016/j.cell.2011.03.044. PMC  3740329. PMID  21529715.
  32. ^ Nakamura, Kensuke; Inokuchi, Ryota; Doi, Kent; Fukuda, Tatsuma; Tokunaga, Kurato; Nakajima, Susumu; Noiri, Eisei; Yahagi, Naoki (2014). "Septic Ketoacidosis". Internal Medicine. 53 (10): 1071–1073. doi: 10.2169/internalmedicine.53.1791. ISSN  0918-2918. PMID  24827487.
  33. ^ Gokhman, David; Lavi, Eitan; Prüfer, Kay; Fraga, Mario F.; Riancho, José A.; Kelso, Janet; Pääbo, Svante; Meshorer, Eran; Carmel, Liran (2014-05-02). "Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan". Science. 344 (6183): 523–527. Bibcode: 2014Sci...344..523G. doi: 10.1126/science.1250368. ISSN  0036-8075. PMID  24786081.
  34. ^ Sagi, Ido; Chia, Gloryn; Golan-Lev, Tamar; Peretz, Mordecai; Weissbein, Uri; Sui, Lina; Sauer, Mark V.; Yanuka, Ofra; Egli, Dieter; Benvenisty, Nissim (2016-04-07). "Derivation and differentiation of haploid human embryonic stem cells". Nature. 532 (7597): 107–111. Bibcode: 2016Natur.532..107S. doi: 10.1038/nature17408. ISSN  0028-0836. PMID  26982723.
  35. ^ Yilmaz, Atilgan; Peretz, Mordecai; Aharony, Aviram; Sagi, Ido; Benvenisty, Nissim (May 2018). "Defining essential genes for human pluripotent stem cells by CRISPR–Cas9 screening in haploid cells". Nature Cell Biology. 20 (5): 610–619. doi: 10.1038/s41556-018-0088-1. ISSN  1465-7392. PMID  29662178.
  36. ^ Bar, Shiran; Vershkov, Dan; Keshet, Gal; Lezmi, Elyad; Meller, Naama; Yilmaz, Atilgan; Yanuka, Ofra; Nissim-Rafinia, Malka; Meshorer, Eran; Eldar-Geva, Talia; Benvenisty, Nissim (2021-11-18). "Identifying regulators of parental imprinting by CRISPR/Cas9 screening in haploid human embryonic stem cells". Nature Communications. 12 (1): 6718. Bibcode: 2021NatCo..12.6718B. doi: 10.1038/s41467-021-26949-7. ISSN  2041-1723. PMC  8602306. PMID  34795250.
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