Donita C. Brady | |
---|---|
Alma mater | Radford University - Chemistry, B.S. University of North Carolina at Chapel Hill, PhD |
Scientific career | |
Fields | Cancer Biology |
Institutions | Duke University School of Medicine, Postdoctoral Researcher with Christopher Counter, 2008-2013 Duke University School of Medicine, Research Associate Senior with Christopher Counter, 2013-2015 |
Thesis | The transforming Rho family GTPase, Wrch-1, regulates epithelial cell morphogenesis through modulating cell junctions and actin cytoskeletal dynamics (May 2008) |
Doctoral advisor | Adrienne D. Cox |
Website | https://www.med.upenn.edu/bradylab/ |
Donita C. Brady is a cancer biologist and the Presidential Associate Professor of Cancer Biology at the Perelman School of Medicine at the University of Pennsylvania. [1] [2] [3] [4] Her research examines how cells communicate through kinases and nutrient homeostasis, and in particular, the central role of copper and other metals in these interactions. [2] [5]
Brady grew up near Virginia Beach and was inspired to purse Chemistry as a result of her AP Chemistry teacher. [5] Brady studied chemistry at Radford University where she graduated magna cum laude. [2] [6] [7]
Brady completed a PhD in pharmacology in 2008 at the University of North Carolina, Chapel Hill in the laboratory of Adrienne D. Cox. [1] [2] [8] As a graduate student, Brady studied how cancer cells exploit normal cellular functions to alter their shape. [8] After graduation, Brady became a postdoctoral fellow (2008 - 2013) and senior research associate (2013 - 2015) in the laboratory of Christopher Counter at Duke University School of Medicine. [1] [2] In 2015, she joined the Department of Cancer Biology in the Perelman School of Medicine at the University of Pennsylvania as an assistant professor. [8] In 2016, Brady was recognized as one of 22 Pew Scholars in Biomedical Sciences by The Pew Charitable Trusts. [9] In 2019, Brady was awarded a grant through the Stuart Scott Memorial Cancer Research Fund to continue her work in PDAC ( pancreatic ductal adenocarcinoma) research. [10]
Brady research focuses on how cells communicate through kinases and nutrient homeostasis, [5] and the central role of metals such as copper in healthy cell physiology and cancer. [1] [8] [11] She discovered that kinases require copper for their ability to function. [5] Brady also showed that by inhibiting a protein called CTR1, which is responsible for importing copper into cells, tumor growth could be slowed in a mouse model. [1]
Brady has received several honors and awards for her research, including:
At Radford University, Brady played Division I softball. [6]
Donita C. Brady | |
---|---|
Alma mater | Radford University - Chemistry, B.S. University of North Carolina at Chapel Hill, PhD |
Scientific career | |
Fields | Cancer Biology |
Institutions | Duke University School of Medicine, Postdoctoral Researcher with Christopher Counter, 2008-2013 Duke University School of Medicine, Research Associate Senior with Christopher Counter, 2013-2015 |
Thesis | The transforming Rho family GTPase, Wrch-1, regulates epithelial cell morphogenesis through modulating cell junctions and actin cytoskeletal dynamics (May 2008) |
Doctoral advisor | Adrienne D. Cox |
Website | https://www.med.upenn.edu/bradylab/ |
Donita C. Brady is a cancer biologist and the Presidential Associate Professor of Cancer Biology at the Perelman School of Medicine at the University of Pennsylvania. [1] [2] [3] [4] Her research examines how cells communicate through kinases and nutrient homeostasis, and in particular, the central role of copper and other metals in these interactions. [2] [5]
Brady grew up near Virginia Beach and was inspired to purse Chemistry as a result of her AP Chemistry teacher. [5] Brady studied chemistry at Radford University where she graduated magna cum laude. [2] [6] [7]
Brady completed a PhD in pharmacology in 2008 at the University of North Carolina, Chapel Hill in the laboratory of Adrienne D. Cox. [1] [2] [8] As a graduate student, Brady studied how cancer cells exploit normal cellular functions to alter their shape. [8] After graduation, Brady became a postdoctoral fellow (2008 - 2013) and senior research associate (2013 - 2015) in the laboratory of Christopher Counter at Duke University School of Medicine. [1] [2] In 2015, she joined the Department of Cancer Biology in the Perelman School of Medicine at the University of Pennsylvania as an assistant professor. [8] In 2016, Brady was recognized as one of 22 Pew Scholars in Biomedical Sciences by The Pew Charitable Trusts. [9] In 2019, Brady was awarded a grant through the Stuart Scott Memorial Cancer Research Fund to continue her work in PDAC ( pancreatic ductal adenocarcinoma) research. [10]
Brady research focuses on how cells communicate through kinases and nutrient homeostasis, [5] and the central role of metals such as copper in healthy cell physiology and cancer. [1] [8] [11] She discovered that kinases require copper for their ability to function. [5] Brady also showed that by inhibiting a protein called CTR1, which is responsible for importing copper into cells, tumor growth could be slowed in a mouse model. [1]
Brady has received several honors and awards for her research, including:
At Radford University, Brady played Division I softball. [6]