Domfront may refer to:

Domfront may refer to one of several communes in France:

• Domfront, Oise, a commune in the Oise department in northern France
• Domfront, Orne, a commune in the Orne department in north-western France until 2015
  • Château de Domfront, a ruined castle in the town of Domfront, Orne
• Domfront-en-Poiraie, a commune in the department of Orne, northwestern France from 2016
• Domfront-en-Champagne, a commune in the Sarthe department in the Pays de la Loire region in north-western France

• Ralph of Domfront (or Radulph, Radulfus; died c. 1146), an archbishop of Mamistra and second Latin patriarch of Antioch (as Ralph I) from 1135 until 1140

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