From Wikipedia, the free encyclopedia
DNA polymerase III, delta subunit
Identifiers
Organism Escherichia coli
(str. K-12 substr. MG1655)
SymbolholA
Entrez 947573
RefSeq (Prot) NP_415173.1
UniProt P28630
Other data
EC number 2.7.7.7
Chromosome genome: 0.67 - 0.67 Mb
Search for
Structures Swiss-model
Domains InterPro
DNA polymerase III, delta subunit
atpgs bound e. coli clamp loader complex
Identifiers
SymbolDNA_pol3_delta
Pfam PF06144
Pfam clan CL0023
InterPro IPR010372
SCOP2 1jql / SCOPe / SUPFAM
Available protein structures:
Pfam   structures / ECOD  
PDB RCSB PDB; PDBe; PDBj
PDBsum structure summary

In molecular biology, the δ (delta) subunit of DNA polymerase III is encoded by the holA gene in E. coli and other bacteria. Along with the γ, δ', χ, and ψ subunits that make up the core polymerase, and the β accessory proteins, the δ subunit is responsible for the high speed and processivity of polIII. [1] [2]

References

  1. ^ Dong Z, Onrust R, Skangalis M, O'Donnell M (June 1993). "DNA polymerase III accessory proteins. I. holA and holB encoding delta and delta'" (PDF). The Journal of Biological Chemistry. 268 (16): 11758–65. doi: 10.1016/S0021-9258(19)50264-2. PMID  8505303.
  2. ^ Carter JR, Franden MA, Aebersold R, McHenry CS (1992). "Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme". Journal of Bacteriology. 174 (21): 7013–25. doi: 10.1128/jb.174.21.7013-7025.1992. PMC  207382. PMID  1400251.
From Wikipedia, the free encyclopedia
DNA polymerase III, delta subunit
Identifiers
Organism Escherichia coli
(str. K-12 substr. MG1655)
SymbolholA
Entrez 947573
RefSeq (Prot) NP_415173.1
UniProt P28630
Other data
EC number 2.7.7.7
Chromosome genome: 0.67 - 0.67 Mb
Search for
Structures Swiss-model
Domains InterPro
DNA polymerase III, delta subunit
atpgs bound e. coli clamp loader complex
Identifiers
SymbolDNA_pol3_delta
Pfam PF06144
Pfam clan CL0023
InterPro IPR010372
SCOP2 1jql / SCOPe / SUPFAM
Available protein structures:
Pfam   structures / ECOD  
PDB RCSB PDB; PDBe; PDBj
PDBsum structure summary

In molecular biology, the δ (delta) subunit of DNA polymerase III is encoded by the holA gene in E. coli and other bacteria. Along with the γ, δ', χ, and ψ subunits that make up the core polymerase, and the β accessory proteins, the δ subunit is responsible for the high speed and processivity of polIII. [1] [2]

References

  1. ^ Dong Z, Onrust R, Skangalis M, O'Donnell M (June 1993). "DNA polymerase III accessory proteins. I. holA and holB encoding delta and delta'" (PDF). The Journal of Biological Chemistry. 268 (16): 11758–65. doi: 10.1016/S0021-9258(19)50264-2. PMID  8505303.
  2. ^ Carter JR, Franden MA, Aebersold R, McHenry CS (1992). "Molecular cloning, sequencing, and overexpression of the structural gene encoding the delta subunit of Escherichia coli DNA polymerase III holoenzyme". Journal of Bacteriology. 174 (21): 7013–25. doi: 10.1128/jb.174.21.7013-7025.1992. PMC  207382. PMID  1400251.

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